IL96081A - Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments - Google Patents

Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments

Info

Publication number
IL96081A
IL96081A IL9608190A IL9608190A IL96081A IL 96081 A IL96081 A IL 96081A IL 9608190 A IL9608190 A IL 9608190A IL 9608190 A IL9608190 A IL 9608190A IL 96081 A IL96081 A IL 96081A
Authority
IL
Israel
Prior art keywords
compound
formula
pyridinyl
amino
indole
Prior art date
Application number
IL9608190A
Other languages
English (en)
Other versions
IL96081A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL96081A0 publication Critical patent/IL96081A0/xx
Publication of IL96081A publication Critical patent/IL96081A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
IL9608190A 1989-10-24 1990-10-22 Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments IL96081A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,712 US4992448A (en) 1989-10-24 1989-10-24 Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders

Publications (2)

Publication Number Publication Date
IL96081A0 IL96081A0 (en) 1991-07-18
IL96081A true IL96081A (en) 1994-12-29

Family

ID=23687722

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9608190A IL96081A (en) 1989-10-24 1990-10-22 Benzocycloalkyl pyridinamines, a process and intermediates for their preparation and their use as medicaments

Country Status (17)

Country Link
US (1) US4992448A (de)
EP (1) EP0428878B1 (de)
JP (1) JPH0725748B2 (de)
KR (1) KR0169109B1 (de)
AT (1) ATE123492T1 (de)
AU (1) AU626470B2 (de)
CA (1) CA2028287C (de)
DE (1) DE69019920T2 (de)
DK (1) DK0428878T3 (de)
ES (1) ES2074508T3 (de)
FI (1) FI905191A7 (de)
IE (1) IE903810A1 (de)
IL (1) IL96081A (de)
NO (1) NO904575L (de)
PH (1) PH27409A (de)
PT (1) PT95651B (de)
ZA (1) ZA908460B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
US5102891A (en) * 1990-07-23 1992-04-07 Hoechst-Roussel Pharmaceuticals Inc. 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates
RO114445B1 (ro) * 1994-05-27 1999-04-30 Smithkline Beecham S.P.A. Derivaţi de chinolină antagonişti ai receptorului nk3 tachichinină,procedeu de preparare,compoziţii farmaceutice pe baza acestora şi metodă de tratament
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
US6339093B1 (en) * 1999-10-08 2002-01-15 Hoffmann-La Roche Inc. Isoquinoline derivatives
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (de) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Arzneiabgabesystem auf glutathion-basis
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
CH498114A (de) * 1967-06-02 1970-10-31 Ruetgerswerke Ag Verfahren zur Herstellung von 2-N-substituierten 2-Amino-5-nitropyridinen
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
US4042697A (en) * 1972-10-19 1977-08-16 Allen & Hanburys Limited Isoquinolium compounds for treating diabetes
US4190660A (en) * 1978-08-11 1980-02-26 Siu Patrick M Anti-drug withdrawal syndrome composition and method of use
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
US4992448A (en) 1991-02-12
EP0428878A2 (de) 1991-05-29
IE903810A1 (en) 1991-04-24
FI905191A7 (fi) 1991-04-25
PT95651A (pt) 1991-09-13
KR0169109B1 (ko) 1999-01-15
AU626470B2 (en) 1992-07-30
PH27409A (en) 1993-06-21
ZA908460B (en) 1991-08-28
DE69019920T2 (de) 1995-11-16
EP0428878B1 (de) 1995-06-07
AU6485890A (en) 1991-05-02
CA2028287C (en) 2001-04-03
KR910007911A (ko) 1991-05-30
IL96081A0 (en) 1991-07-18
CA2028287A1 (en) 1991-04-25
ES2074508T3 (es) 1995-09-16
EP0428878A3 (en) 1991-09-25
DK0428878T3 (da) 1995-10-16
JPH03151378A (ja) 1991-06-27
NO904575D0 (no) 1990-10-23
NO904575L (no) 1991-04-25
JPH0725748B2 (ja) 1995-03-22
FI905191A0 (fi) 1990-10-22
DE69019920D1 (de) 1995-07-13
ATE123492T1 (de) 1995-06-15
PT95651B (pt) 1997-12-31

Similar Documents

Publication Publication Date Title
US4983615A (en) Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
US4970219A (en) Heteroarylamino- and heteroaryloxypyridinamine compounds which have useful utility in treating skin disorders
US5166170A (en) 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
US5985894A (en) N-substituted quinolines
CA2092404A1 (en) Indole derivatives as antiallergy and antiinflammatory agents
CA2028287C (en) Benzocycloalkylaminopyridinamines and related compounds, a process and intermediates for their preparation and their use as medicaments
US4931457A (en) Naphthylamino-and naphthyloxy-pyridinamine comounds useful as topical antiinflammatory agents for the treatment of skin disorders
US5034403A (en) Heteroarylamino-and heteroaryloxypyridinamines and related compounds
US5037835A (en) Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders
US4959378A (en) Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders
US5221682A (en) Heteroarylamino- and heteroaryloxypyridinamines and related compounds
US5059602A (en) 4-substituted dihydropyrido(4,3-d)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders
US4959377A (en) Phenoxypyridinamine compounds which are use as a dermatological composition
US5095019A (en) 4-substituted dihydropyrido(4,3-D)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders
US4279913A (en) Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines
JPH07119200B2 (ja) ナフチルスルホニルアルキルカルボン酸誘導体

Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
RH Patent void