DE69017820T2 - Implantaten für grosse mengen von zellen auf polymerische matrizen. - Google Patents
Implantaten für grosse mengen von zellen auf polymerische matrizen.Info
- Publication number
- DE69017820T2 DE69017820T2 DE69017820T DE69017820T DE69017820T2 DE 69017820 T2 DE69017820 T2 DE 69017820T2 DE 69017820 T DE69017820 T DE 69017820T DE 69017820 T DE69017820 T DE 69017820T DE 69017820 T2 DE69017820 T2 DE 69017820T2
- Authority
- DE
- Germany
- Prior art keywords
- degradable
- cells
- matrix
- function
- growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/18—Liver cell growth factor (LCGF, Gly-His-Lys)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34315889A | 1989-04-25 | 1989-04-25 | |
PCT/US1990/002257 WO1990012604A1 (en) | 1989-04-25 | 1990-04-25 | Method for implanting large volumes of cells on polymeric matrices |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69017820D1 DE69017820D1 (de) | 1995-04-20 |
DE69017820T2 true DE69017820T2 (de) | 1995-10-05 |
Family
ID=23344941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69017820T Expired - Lifetime DE69017820T2 (de) | 1989-04-25 | 1990-04-25 | Implantaten für grosse mengen von zellen auf polymerische matrizen. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0422209B1 (de) |
JP (3) | JP3073766B2 (de) |
AT (1) | ATE119787T1 (de) |
AU (1) | AU636346B2 (de) |
CA (1) | CA2031532C (de) |
DE (1) | DE69017820T2 (de) |
ES (1) | ES2072434T3 (de) |
WO (1) | WO1990012604A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6309635B1 (en) | 1986-11-20 | 2001-10-30 | Children's Medical Center Corp. | Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo |
US5376118A (en) * | 1989-05-10 | 1994-12-27 | United States Surgical Corporation | Support material for cell impregnation |
WO1991008718A1 (en) * | 1989-12-07 | 1991-06-27 | Biosynthesis, Inc. | Hollow viscus prosthesis and method of implantation |
ATE233809T1 (de) * | 1990-10-19 | 2003-03-15 | Univ New York | Eine methode zur transplantation von zellen in das gehirn und ihre therapeutische verwendung |
US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
US5849686A (en) * | 1991-03-11 | 1998-12-15 | Creative Biomolecules, Inc. | Morphogen-induced liver regeneration |
WO1993007913A1 (en) * | 1991-10-24 | 1993-04-29 | Children's Medical Center Corporation | Neomorphogenesis of urological structures in vivo from cell culture |
EP0610423B1 (de) * | 1991-10-30 | 1997-05-07 | Massachusetts Institute Of Technology | Vorvaskularisierte polymerimplantate für organtransplantation |
US5610753A (en) | 1991-12-12 | 1997-03-11 | Eastman Kodak Company | Optical design of laser scanner to reduce thermal sensitivity |
DE4206585C2 (de) * | 1992-03-03 | 1994-11-24 | Augustinus Dr Med Bader | Vorrichtung zur Massenkultur von Zellen |
WO1993019701A1 (en) * | 1992-04-01 | 1993-10-14 | Baxter International Inc. | Angiogenic tissue implant systems and methods |
GB9210574D0 (en) * | 1992-05-18 | 1992-07-01 | Ca Nat Research Council | Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications |
CA2140905A1 (en) * | 1992-07-29 | 1994-01-30 | Keith E. Dionne | Use of pouch of implantation of living cells |
ATE162078T1 (de) | 1992-09-16 | 1998-01-15 | Creative Biomolecules Inc | Morphogeninduzierte regenerierung der leber |
US6689608B1 (en) | 1993-02-01 | 2004-02-10 | Massachusetts Institute Of Technology | Porous biodegradable polymeric materials for cell transplantation |
WO1994025079A1 (en) * | 1993-04-23 | 1994-11-10 | Massachusetts Institute Of Technology | Porous biodegradable polymeric materials for cell transplantation |
ATE183078T1 (de) * | 1993-08-10 | 1999-08-15 | Gore & Ass | Zelleinkapselungsvorrichtung |
US5549675A (en) * | 1994-01-11 | 1996-08-27 | Baxter International, Inc. | Method for implanting tissue in a host |
US20020055786A1 (en) | 1994-08-16 | 2002-05-09 | Anthony Atala | Reconstruction of urological structures with polymeric matrices |
US5648088A (en) | 1995-03-06 | 1997-07-15 | Ethicon, Inc. | Blends of absorbable polyoxaesters containing amines and/or amide groups |
US5855610A (en) | 1995-05-19 | 1999-01-05 | Children's Medical Center Corporation | Engineering of strong, pliable tissues |
WO1997010807A1 (en) * | 1995-09-22 | 1997-03-27 | Gore Hybrid Technologies, Inc. | Improved cell encapsulation device |
DE69631402T2 (de) | 1995-11-06 | 2004-12-09 | Ethicon, Inc. | Polymermischungen die Polyoxaestern und Lactonpolymeren enthalten |
US5916585A (en) * | 1996-06-03 | 1999-06-29 | Gore Enterprise Holdings, Inc. | Materials and method for the immobilization of bioactive species onto biodegradable polymers |
US6316522B1 (en) | 1997-08-18 | 2001-11-13 | Scimed Life Systems, Inc. | Bioresorbable hydrogel compositions for implantable prostheses |
WO1999022781A2 (en) | 1997-10-31 | 1999-05-14 | Children's Medical Center Corporation | Bladder reconstruction |
CA2326819A1 (en) * | 1998-04-24 | 1999-11-04 | Transkaryotic Therapies, Inc. | Delivery of therapeutic proteins via implantation of genetically modified cells in the omentum |
US6129757A (en) | 1998-05-18 | 2000-10-10 | Scimed Life Systems | Implantable members for receiving therapeutically useful compositions |
US6245345B1 (en) * | 1998-07-07 | 2001-06-12 | Atrix Laboratories, Inc. | Filamentous porous films and methods for producing the same |
WO2002030481A1 (en) * | 2000-10-10 | 2002-04-18 | Massachusetts Institute Of Technology | Cell delivery using controllably degradable mesh-gel constructs |
KR20010044624A (ko) * | 2001-03-12 | 2001-06-05 | 정재호 | 연골조직공학을 위한 연골지지체의 제조방법 및 이연골지지체를 사용하여 제조한 인공연골 |
US7034037B2 (en) | 2001-06-29 | 2006-04-25 | Ethicon, Inc. | Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin |
US7030127B2 (en) | 2001-06-29 | 2006-04-18 | Ethicon, Inc. | Composition and medical devices utilizing bioabsorbable polymeric waxes |
US6967234B2 (en) | 2002-12-18 | 2005-11-22 | Ethicon, Inc. | Alkyd-lactone copolymers for medical applications |
US7005136B2 (en) | 2002-03-29 | 2006-02-28 | Ethicon, Inc. | Bone replacement materials utilizing bioabsorbable liquid polymers |
US7326426B2 (en) | 2002-03-29 | 2008-02-05 | Ethicon, Inc. | Compositions and medical devices utilizing bioabsorbable liquid polymers |
US7368125B2 (en) | 2002-06-05 | 2008-05-06 | Ethicon, Inc. | Amphiphilic polymers for medical applications |
US7026374B2 (en) | 2002-06-25 | 2006-04-11 | Aruna Nathan | Injectable microdispersions for medical applications |
US7101566B2 (en) | 2002-06-28 | 2006-09-05 | Ethicon, Inc. | Polymer coated microparticles for sustained release |
US6872799B2 (en) | 2002-12-18 | 2005-03-29 | Ethicon, Inc. | Functionalized polymers for medical applications |
US6866860B2 (en) | 2002-12-19 | 2005-03-15 | Ethicon, Inc. | Cationic alkyd polyesters for medical applications |
DK1948259T3 (en) | 2005-10-26 | 2017-04-10 | Genesis Tech Ltd | ACELLULAR BIOabsorbable Tissue Regeneration Matrices Produced by Incubation of ACELLULAR BLOOD PRODUCTS |
EP2162529B1 (de) | 2007-06-08 | 2019-03-27 | Wake Forest University Health Sciences | Selektive zelltherapie zur behandlung von nierenversagen |
US10590391B2 (en) | 2007-06-08 | 2020-03-17 | Wake Forest University Health Sciences | Selective cell therapy for the treatment of renal failure |
NZ601862A (en) | 2008-11-12 | 2014-07-25 | Tengion Inc | Isolated renal cells and uses thereof |
WO2010057015A1 (en) | 2008-11-14 | 2010-05-20 | Wake Forest University Health Sciences | Kidney structures and methods of forming the same |
JP5974215B2 (ja) | 2010-05-12 | 2016-08-24 | リージェンメド(ケイマン)エルティーディー. | 生理活性腎臓細胞 |
US9386863B1 (en) | 2010-06-18 | 2016-07-12 | Boba Inc. | Child carrier and methods of use |
WO2012064369A1 (en) | 2010-11-10 | 2012-05-18 | Tengion, Inc. | Injectable formulations for organ augmentation |
US11123372B2 (en) | 2016-07-29 | 2021-09-21 | Prokidney | Bioactive renal cells for the treatment of chronic kidney disease |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4637931A (en) * | 1984-10-09 | 1987-01-20 | The United States Of America As Represented By The Secretary Of The Army | Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material |
CH670760A5 (de) * | 1986-06-02 | 1989-07-14 | Sulzer Ag | |
CA1340581C (en) * | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
US5041138A (en) * | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
-
1990
- 1990-04-25 DE DE69017820T patent/DE69017820T2/de not_active Expired - Lifetime
- 1990-04-25 EP EP90907948A patent/EP0422209B1/de not_active Expired - Lifetime
- 1990-04-25 AT AT90907948T patent/ATE119787T1/de not_active IP Right Cessation
- 1990-04-25 AU AU55691/90A patent/AU636346B2/en not_active Expired
- 1990-04-25 JP JP02507248A patent/JP3073766B2/ja not_active Expired - Lifetime
- 1990-04-25 WO PCT/US1990/002257 patent/WO1990012604A1/en active IP Right Grant
- 1990-04-25 CA CA002031532A patent/CA2031532C/en not_active Expired - Lifetime
- 1990-04-25 ES ES90907948T patent/ES2072434T3/es not_active Expired - Lifetime
-
1998
- 1998-03-18 JP JP10069123A patent/JPH10263070A/ja active Pending
-
2001
- 2001-05-14 JP JP2001144028A patent/JP2001314498A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69017820D1 (de) | 1995-04-20 |
JPH04501080A (ja) | 1992-02-27 |
WO1990012604A1 (en) | 1990-11-01 |
CA2031532A1 (en) | 1990-10-26 |
JP3073766B2 (ja) | 2000-08-07 |
CA2031532C (en) | 2003-02-25 |
AU636346B2 (en) | 1993-04-29 |
JPH10263070A (ja) | 1998-10-06 |
ATE119787T1 (de) | 1995-04-15 |
AU5569190A (en) | 1990-11-16 |
EP0422209B1 (de) | 1995-03-15 |
ES2072434T3 (es) | 1995-07-16 |
JP2001314498A (ja) | 2001-11-13 |
EP0422209A1 (de) | 1991-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |