DE69016528D1 - Oxadiazolyl-Phenoxyalkyl-Isoxazole und ihre Verwendung als antivirale Mittel. - Google Patents

Oxadiazolyl-Phenoxyalkyl-Isoxazole und ihre Verwendung als antivirale Mittel.

Info

Publication number
DE69016528D1
DE69016528D1 DE69016528T DE69016528T DE69016528D1 DE 69016528 D1 DE69016528 D1 DE 69016528D1 DE 69016528 T DE69016528 T DE 69016528T DE 69016528 T DE69016528 T DE 69016528T DE 69016528 D1 DE69016528 D1 DE 69016528D1
Authority
DE
Germany
Prior art keywords
alkyl
antiviral agents
phenoxyalkyl
isoxazoles
oxadiazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016528T
Other languages
English (en)
Other versions
DE69016528T2 (de
Inventor
Guy Dominic Diana
Thomas Robert Bailey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/396,419 external-priority patent/US4945164A/en
Priority claimed from US07/396,414 external-priority patent/US4942241A/en
Priority claimed from US07/532,480 external-priority patent/US5175178A/en
Priority claimed from US07/534,917 external-priority patent/US5110821A/en
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of DE69016528D1 publication Critical patent/DE69016528D1/de
Application granted granted Critical
Publication of DE69016528T2 publication Critical patent/DE69016528T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
DE69016528T 1989-08-18 1990-08-13 Oxadiazolyl-Phenoxyalkyl-Isoxazole und ihre Verwendung als antivirale Mittel. Expired - Fee Related DE69016528T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/396,419 US4945164A (en) 1989-08-18 1989-08-18 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US07/396,414 US4942241A (en) 1989-08-21 1989-08-21 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US07/532,480 US5175178A (en) 1989-08-21 1990-06-04 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US07/534,917 US5110821A (en) 1989-08-18 1990-06-07 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (2)

Publication Number Publication Date
DE69016528D1 true DE69016528D1 (de) 1995-03-16
DE69016528T2 DE69016528T2 (de) 1995-08-24

Family

ID=27503394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016528T Expired - Fee Related DE69016528T2 (de) 1989-08-18 1990-08-13 Oxadiazolyl-Phenoxyalkyl-Isoxazole und ihre Verwendung als antivirale Mittel.

Country Status (14)

Country Link
EP (1) EP0413289B1 (de)
JP (1) JP3125793B2 (de)
KR (1) KR100197853B1 (de)
AT (1) ATE118005T1 (de)
AU (1) AU634567B2 (de)
DE (1) DE69016528T2 (de)
DK (1) DK0413289T3 (de)
ES (1) ES2070961T3 (de)
FI (1) FI96862C (de)
IE (1) IE68848B1 (de)
IL (1) IL95275A (de)
MY (1) MY106979A (de)
NO (1) NO180487C (de)
NZ (1) NZ234760A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5453433A (en) * 1994-05-13 1995-09-26 Sterling Winthrop Inc. Thiadiazoles and antipicornaviral compositions
DE19643037A1 (de) * 1996-10-18 1998-04-23 Boehringer Ingelheim Kg Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
PL2059513T3 (pl) * 2006-09-08 2013-06-28 Ptc Therapeutics Inc Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1023383A (de) *
DE2722331A1 (de) * 1976-05-18 1977-11-24 Ricoh Kk 1,3,4-oxadiazolderivate sowie diese enthaltende elektrophotographische aufzeichnungsmaterialien
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof

Also Published As

Publication number Publication date
FI903886A0 (fi) 1990-08-06
MY106979A (en) 1995-08-30
JP3125793B2 (ja) 2001-01-22
KR910004612A (ko) 1991-03-29
FI96862C (fi) 1996-09-10
IE902973A1 (en) 1991-02-27
NO180487C (no) 1997-04-30
DK0413289T3 (da) 1995-03-27
FI96862B (fi) 1996-05-31
EP0413289A3 (en) 1991-08-07
NO180487B (no) 1997-01-20
EP0413289B1 (de) 1995-02-01
NZ234760A (en) 1991-09-25
JPH03130283A (ja) 1991-06-04
NO903613L (no) 1991-02-19
AU634567B2 (en) 1993-02-25
NO903613D0 (no) 1990-08-16
IE68848B1 (en) 1996-07-24
AU6104190A (en) 1991-02-21
IL95275A0 (en) 1991-06-30
KR100197853B1 (ko) 1999-06-15
ES2070961T3 (es) 1995-06-16
EP0413289A2 (de) 1991-02-20
DE69016528T2 (de) 1995-08-24
ATE118005T1 (de) 1995-02-15
IL95275A (en) 1995-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8328 Change in the person/name/address of the agent

Free format text: MUELLER, SCHUPFNER & GAUGER, 80539 MUENCHEN

8339 Ceased/non-payment of the annual fee