DE69006707D1 - Verwendung von Fluorochinolon-Derivaten zur Behandlung der Pneumocystis carinii Pneumonie. - Google Patents

Verwendung von Fluorochinolon-Derivaten zur Behandlung der Pneumocystis carinii Pneumonie.

Info

Publication number
DE69006707D1
DE69006707D1 DE90403501T DE69006707T DE69006707D1 DE 69006707 D1 DE69006707 D1 DE 69006707D1 DE 90403501 T DE90403501 T DE 90403501T DE 69006707 T DE69006707 T DE 69006707T DE 69006707 D1 DE69006707 D1 DE 69006707D1
Authority
DE
Germany
Prior art keywords
treatment
pneumocystis carinii
carinii pneumonia
derivatives
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90403501T
Other languages
English (en)
Other versions
DE69006707T2 (de
Inventor
Marc Gentilini
Anne Guyot
Michel Rosenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of DE69006707D1 publication Critical patent/DE69006707D1/de
Publication of DE69006707T2 publication Critical patent/DE69006707T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69006707T 1989-12-11 1990-12-10 Verwendung von Fluorochinolon-Derivaten zur Behandlung der Pneumocystis carinii Pneumonie. Expired - Fee Related DE69006707T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8916324A FR2655545B1 (fr) 1989-12-11 1989-12-11 Nouvelle application therapeutique des derives des fluoroquinolones.

Publications (2)

Publication Number Publication Date
DE69006707D1 true DE69006707D1 (de) 1994-03-24
DE69006707T2 DE69006707T2 (de) 1994-06-09

Family

ID=9388344

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69006707T Expired - Fee Related DE69006707T2 (de) 1989-12-11 1990-12-10 Verwendung von Fluorochinolon-Derivaten zur Behandlung der Pneumocystis carinii Pneumonie.

Country Status (16)

Country Link
US (1) US5179096A (de)
EP (1) EP0437128B1 (de)
JP (1) JPH03251532A (de)
KR (1) KR910011259A (de)
AT (1) ATE101518T1 (de)
AU (1) AU626743B2 (de)
CA (1) CA2031886A1 (de)
DE (1) DE69006707T2 (de)
DK (1) DK0437128T3 (de)
ES (1) ES2062464T3 (de)
FR (1) FR2655545B1 (de)
HU (1) HU207947B (de)
IE (1) IE64720B1 (de)
IL (1) IL96618A (de)
PT (1) PT96164B (de)
ZA (1) ZA909886B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT67395A (en) * 1993-07-13 1995-04-28 Somfai Method for the n-cyclopropylation of primary and secondary aromatic amines
US5707551A (en) * 1994-12-22 1998-01-13 Rhone-Poulenc Inc. Nonaqueous suspension concentrates of highly water-soluble solids
US5906962A (en) * 1994-12-22 1999-05-25 Rhodia Inc. Non-aqueous suspension concentrates of highly water-soluble solids
US6024979A (en) * 1995-06-06 2000-02-15 Solvay Animal Health, Inc. Oral veterinary composition containing a fluoroquinolone antibacterial agent possessing superior absorption properties and an extended duration of therapeutic antimicrobial blood levels, and a method of treating a microbial infection in a ruminant
US5686095A (en) * 1995-10-23 1997-11-11 Price, Jr.; Francis W. Method of treating canker sores
ES2319699T3 (es) * 1996-05-20 2009-05-11 Otsuka Pharmaceutical Co., Ltd. Remedio para la rosacea.
JPH10143977A (ja) 1996-09-10 1998-05-29 Sony Corp ディスク装置およびそれを用いたビデオカメラ装置
US6060474A (en) * 1998-11-05 2000-05-09 New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery Method for preventing scar tissue formation
US6346391B1 (en) * 1999-07-22 2002-02-12 Trustees Of Tufts College Methods of reducing microbial resistance to drugs
DE502004011696D1 (de) * 2003-02-10 2010-11-11 Bayer Schering Pharma Ag Behandlung bakterieller erkrankungen der atmungsorgane durch lokale applikation von fluorchinolonen
EP2056709A4 (de) * 2006-08-11 2013-05-01 Univ New Jersey Med Zweifachsensibilisator mit lumineszenzverbindungen, konjugaten und verwendung
US9221759B2 (en) 2010-01-13 2015-12-29 Rutgers, The State University Of New Jersey Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292317A (en) * 1977-09-20 1981-09-29 Laboratorie Roger Bellon 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
GB1598915A (en) * 1977-09-20 1981-09-23 Bellon Labor Sa Roger 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4620007A (en) * 1980-09-03 1986-10-28 Bayer Aktiengesellschaft 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
US4551456A (en) * 1983-11-14 1985-11-05 Merck & Co., Inc. Ophthalmic use of norfloxacin and related antibiotics
US4774246A (en) * 1984-01-26 1988-09-27 Abbott Laboratories Quinoline antibacterial compounds
EP0154780B1 (de) * 1984-01-26 1990-04-11 Abbott Laboratories Antibakterielle Chinolinderivate
DE3517709A1 (de) * 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
DK170473B1 (da) * 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
AU594983B2 (en) 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
DE3601566A1 (de) * 1986-01-21 1987-07-23 Bayer Ag Pharmazeutische zubereitungen von ciprofloxacin
DE3632222A1 (de) * 1986-09-23 1988-04-07 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren
DE3637649A1 (de) * 1986-10-13 1988-04-14 Uwe Dr Spohr Verwendung von 4-chinolon-derivaten zur bekaempfung von protozoen und helminthen
DE3704907A1 (de) * 1987-02-17 1988-08-25 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
IT1231425B (it) * 1987-10-05 1991-12-04 Prodotti Antibiotici Spa Procedimento per la sintesi di un derivato dell'acido benzo (ij) chinolizin-2-carbossilico
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US4978661A (en) * 1988-09-29 1990-12-18 Innocenzo Caruso Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis

Also Published As

Publication number Publication date
FR2655545B1 (fr) 1994-06-10
DE69006707T2 (de) 1994-06-09
FR2655545A1 (fr) 1991-06-14
EP0437128A3 (en) 1992-09-30
US5179096A (en) 1993-01-12
EP0437128B1 (de) 1994-02-16
PT96164B (pt) 1998-04-30
AU626743B2 (en) 1992-08-06
HU908146D0 (en) 1991-06-28
IL96618A (en) 1995-05-26
ES2062464T3 (es) 1994-12-16
AU6786290A (en) 1991-06-13
DK0437128T3 (da) 1994-03-14
KR910011259A (ko) 1991-08-07
IL96618A0 (en) 1991-09-16
PT96164A (pt) 1991-09-30
CA2031886A1 (fr) 1991-06-12
HU207947B (en) 1993-07-28
EP0437128A2 (de) 1991-07-17
IE64720B1 (en) 1995-08-23
IE904449A1 (en) 1991-06-19
ZA909886B (en) 1991-09-25
JPH03251532A (ja) 1991-11-11
ATE101518T1 (de) 1994-03-15
HUT55991A (en) 1991-07-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee