DE68928545D1 - Herstellung von glukoseoxidase in rekombinanten systemen - Google Patents

Herstellung von glukoseoxidase in rekombinanten systemen

Info

Publication number
DE68928545D1
DE68928545D1 DE68928545T DE68928545T DE68928545D1 DE 68928545 D1 DE68928545 D1 DE 68928545D1 DE 68928545 T DE68928545 T DE 68928545T DE 68928545 T DE68928545 T DE 68928545T DE 68928545 D1 DE68928545 D1 DE 68928545D1
Authority
DE
Germany
Prior art keywords
glucose oxidase
production
recombinant systems
provides recombinant
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68928545T
Other languages
English (en)
Other versions
DE68928545T2 (de
Inventor
Steven Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DE68928545D1 publication Critical patent/DE68928545D1/de
Publication of DE68928545T2 publication Critical patent/DE68928545T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
DE68928545T 1988-06-21 1989-06-20 Herstellung von glukoseoxidase in rekombinanten systemen Expired - Lifetime DE68928545T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20953088A 1988-06-21 1988-06-21
US07/366,377 US5094951A (en) 1988-06-21 1989-06-19 Production of glucose oxidase in recombinant systems
PCT/US1989/002696 WO1989012675A1 (en) 1988-06-21 1989-06-20 Production of glucose oxidase in recombinant systems

Publications (2)

Publication Number Publication Date
DE68928545D1 true DE68928545D1 (de) 1998-02-19
DE68928545T2 DE68928545T2 (de) 1998-05-14

Family

ID=26904249

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928545T Expired - Lifetime DE68928545T2 (de) 1988-06-21 1989-06-20 Herstellung von glukoseoxidase in rekombinanten systemen

Country Status (10)

Country Link
US (1) US5094951A (de)
EP (1) EP0379556B1 (de)
JP (1) JP2988678B2 (de)
AT (1) ATE162221T1 (de)
CA (1) CA1334940C (de)
DE (1) DE68928545T2 (de)
DK (1) DK175658B1 (de)
NO (1) NO306024B1 (de)
RU (1) RU2228357C2 (de)
WO (1) WO1989012675A1 (de)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003557A1 (en) * 1990-08-17 1992-03-05 Majesty (Her) In Right Of Canada As Represented By The National Research Council Of Canada RECOMBINANT DNA PRODUCTION OF β-1,3-GLUCANASE
DE4301904A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh Hypoglycosylierte recombinante Glucoseoxidase
DE4301932A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh Hefewirtsstämme mit Defekten in der N-Glycosylierung
FR2712891B1 (fr) * 1993-11-22 1996-02-02 Roquette Freres Procédé de purification d'un polymère soluble hypocalorique du glucose et produit ainsi obtenu.
PL178652B1 (pl) * 1993-11-24 2000-05-31 Monsanto Co Zrekombinowana cząsteczka dwuniciowego DNA, sposób wytwarzania genetycznie stransformowanych, odpornych na choroby roślin, oraz genetycznie stransformowana komórka roślinna ziemniaka lub pszenicy
BE1009488A4 (fr) * 1994-06-17 1997-04-01 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1008267A3 (fr) * 1994-01-28 1996-03-05 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1008737A3 (fr) * 1994-01-28 1996-07-02 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
AUPM379294A0 (en) * 1994-02-10 1994-03-03 Commonwealth Scientific And Industrial Research Organisation Expression of the glucose oxidase gene in transgenic organisms
US5834280A (en) * 1994-05-03 1998-11-10 Novo Nordisk A/S Glucose oxidases obtained from a cladosporium
AR002301A1 (es) * 1995-06-07 1998-03-11 Dupont Nutrition Biosci Aps Un método para producir un polipéptido que tiene actividad hexosa oxidasa polipéptido asi obtenido molecula de dna recombinante alli utilizada celula microbiana que comprende dicha molecula metodos para preparar un producto alimenticio un forraje para animales un producto farmacéutico un producto cosmetico un producto para el cuidado dental y un producto horneado para reducir el contenido de azucar de un producto alimenticio para analizar el contenido de un azucar en una muestra o para preparar
US20050287250A1 (en) * 1995-06-07 2005-12-29 Danisco A/S Method
US8178090B2 (en) 1995-06-07 2012-05-15 Danisco A/S Recombinant hexose oxidase
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
CN1080536C (zh) 1995-06-07 2002-03-13 丹尼司可公司 改进面团性质的方法和面团改进组合物以及改进的食品
US7745599B1 (en) 1995-06-07 2010-06-29 Danisco A/S Hexose oxidase-encoding DNAs and methods of use thereof
US5882943A (en) * 1996-07-31 1999-03-16 Aldeen; William Erick Filtration apparatus, kit and method for processing parasite samples
US5879921A (en) * 1996-11-07 1999-03-09 Novo Nordisk A/S Recombinant expression of a glucose oxidase from a cladosporium strain
ATE227844T1 (de) * 1997-02-06 2002-11-15 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
US6303326B1 (en) 1997-12-04 2001-10-16 University Of Arkansas Insect salivary enzyme triggers systemic resistance
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
US6338790B1 (en) * 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) * 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
EP1192269A2 (de) 1999-06-18 2002-04-03 Therasense, Inc. Stofftransportliitierrter in vivo sensor
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US20060091006A1 (en) * 1999-11-04 2006-05-04 Yi Wang Analyte sensor with insertion monitor, and methods
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2002078512A2 (en) 2001-04-02 2002-10-10 Therasense, Inc. Blood glucose tracking apparatus and methods
US6915147B2 (en) 2001-09-07 2005-07-05 Medtronic Minimed, Inc. Sensing apparatus and process
US8506550B2 (en) * 2001-09-07 2013-08-13 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US7323142B2 (en) * 2001-09-07 2008-01-29 Medtronic Minimed, Inc. Sensor substrate and method of fabricating same
US7025760B2 (en) * 2001-09-07 2006-04-11 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US6671554B2 (en) 2001-09-07 2003-12-30 Medtronic Minimed, Inc. Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same
US6809507B2 (en) * 2001-10-23 2004-10-26 Medtronic Minimed, Inc. Implantable sensor electrodes and electronic circuitry
US8465466B2 (en) 2001-10-23 2013-06-18 Medtronic Minimed, Inc Method and system for non-vascular sensor implantation
US7192766B2 (en) * 2001-10-23 2007-03-20 Medtronic Minimed, Inc. Sensor containing molded solidified protein
US20040137547A1 (en) * 2001-12-28 2004-07-15 Medtronic Minimed, Inc. Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property
US7736309B2 (en) * 2002-09-27 2010-06-15 Medtronic Minimed, Inc. Implantable sensor method and system
DK2294928T3 (da) 2002-10-11 2014-11-10 Novozymes As Fremgangsmåde til fremstilling af et varmebehandlet produkt
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
CA2536782A1 (en) 2003-09-11 2005-03-17 Novozymes A/S Recombinant production of antimicrobial agents
US7306641B2 (en) * 2003-09-12 2007-12-11 Hewlett-Packard Development Company, L.P. Integral fuel cartridge and filter
EP1718198A4 (de) 2004-02-17 2008-06-04 Therasense Inc Verfahren und system zur bereitstellung einer datenkommunikation in einem kontinuierlichen blutzuckerüberwachungs- und managementsystem
EP2009093A3 (de) * 2004-09-22 2009-04-08 Bioworks, Inc. Transgene Trichoderm-Stämme und ihre Verwendung bei der Biokontrolle
NZ594810A (en) * 2005-03-15 2012-12-21 Verenium Corp Cellulases, nucleic acids encoding them and methods for making and using them
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
WO2008079227A1 (en) 2006-12-20 2008-07-03 Danisco Us, Inc., Genencor Division Storage-stable glucose oxidase
AU2008210434C8 (en) 2007-01-31 2014-03-27 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
BRPI0809366B8 (pt) 2007-03-28 2021-05-25 Harvard College polipeptídeo substancialmente alfa-helicoidal, método para fabricação do mesmo, aminoácido e composição farmacêutica
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
EP2342221B1 (de) * 2008-09-22 2018-11-07 Aileron Therapeutics, Inc. Verfahren zur herstellung aufgereinigter polypeptidzusammensetzungen
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100213057A1 (en) * 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
CA2756932C (en) 2009-03-31 2020-03-10 Danisco A/S Prevention of extract darkening and malodor formation during solubilization of plant cell wall material
WO2010127050A1 (en) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
EP2482720A4 (de) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc Verfahren und vorrichtung zur bereitstellung einer benachrichtigungsfunktion in analytüberwachungssystemen
EP2415863A1 (de) 2010-08-03 2012-02-08 B.R.A.I.N. Glukoseoxidase Mutante
US8859723B2 (en) 2010-08-13 2014-10-14 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN108929375A (zh) 2011-10-18 2018-12-04 爱勒让治疗公司 拟肽大环化合物
EP2775918B1 (de) 2011-11-07 2020-02-12 Abbott Diabetes Care Inc. Analytüberwachungsvorrichtung und -verfahren
US8927500B2 (en) 2012-02-15 2015-01-06 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US8987414B2 (en) 2012-02-15 2015-03-24 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス,インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
JP6427110B2 (ja) 2013-01-28 2018-11-21 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト アスペルギルスニガー由来の新規グルコース酸化酵素
EP2796547B1 (de) 2013-04-24 2016-09-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Neuartige Glucoseoxidasevarianten
SG10201902594QA (en) 2014-09-24 2019-04-29 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
US10905739B2 (en) 2014-09-24 2021-02-02 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
MX2017011834A (es) 2015-03-20 2018-04-11 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
US10344078B2 (en) * 2015-05-01 2019-07-09 Inhibrx, Inc. Type III secretion system targeting molecules
EP3347372A4 (de) 2015-09-10 2019-09-04 Aileron Therapeutics, Inc. Peptidomimetische makrocyclen als modulatoren von mcl-1
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701715A (en) * 1971-02-04 1972-10-31 Dawe S Lab Inc Method for the production of glucose oxidase

Also Published As

Publication number Publication date
JPH03500008A (ja) 1991-01-10
ATE162221T1 (de) 1998-01-15
NO306024B1 (no) 1999-09-06
EP0379556A4 (en) 1992-03-11
EP0379556A1 (de) 1990-08-01
US5094951A (en) 1992-03-10
DK175658B1 (da) 2005-01-10
WO1989012675A1 (en) 1989-12-28
JP2988678B2 (ja) 1999-12-13
EP0379556B1 (de) 1998-01-14
DE68928545T2 (de) 1998-05-14
NO900770L (no) 1990-04-23
RU2228357C2 (ru) 2004-05-10
DK45190A (da) 1990-04-10
DK45190D0 (da) 1990-02-20
NO900770D0 (no) 1990-02-19
CA1334940C (en) 1995-03-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: ACKMANN MENGES PATENT- UND RECHTSANWAELTE, 80469 M

8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US