DE68924591T2 - DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge. - Google Patents

DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge.

Info

Publication number
DE68924591T2
DE68924591T2 DE68924591T DE68924591T DE68924591T2 DE 68924591 T2 DE68924591 T2 DE 68924591T2 DE 68924591 T DE68924591 T DE 68924591T DE 68924591 T DE68924591 T DE 68924591T DE 68924591 T2 DE68924591 T2 DE 68924591T2
Authority
DE
Germany
Prior art keywords
dna detection
charge neutral
sample strands
neutral sample
strands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68924591T
Other languages
English (en)
Other versions
DE68924591D1 (de
Inventor
Joseph Eugene Celebuski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE68924591D1 publication Critical patent/DE68924591D1/de
Application granted granted Critical
Publication of DE68924591T2 publication Critical patent/DE68924591T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE68924591T 1989-08-01 1989-08-03 DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge. Expired - Fee Related DE68924591T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA000607194A CA1337639C (en) 1989-08-01 1989-08-01 Dna probe assay using neutrally charged probe strands
EP89114346A EP0411186B1 (de) 1989-08-01 1989-08-03 DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge
JP1204559A JP2912385B2 (ja) 1989-08-01 1989-08-04 Ｄｎａプローブアッセイおよびそれに用いるキット

Publications (2)

Publication Number Publication Date
DE68924591D1 DE68924591D1 (de) 1995-11-23
DE68924591T2 true DE68924591T2 (de) 1996-05-15

Family

ID=27168401

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924591T Expired - Fee Related DE68924591T2 (de) 1989-08-01 1989-08-03 DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge.

Country Status (5)

Country Link
EP (1) EP0411186B1 (de)
JP (1) JP2912385B2 (de)
CA (1) CA1337639C (de)
DE (1) DE68924591T2 (de)
ES (1) ES2080737T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872816B1 (en) 1996-01-24 2005-03-29 Third Wave Technologies, Inc. Nucleic acid detection kits
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5994069A (en) 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
AU4661193A (en) * 1992-06-30 1994-01-24 Research Corporation Technologies, Inc. Pentavalent synthesis of oligonucleotides containing stereospecific alkylphosphonates and arylphosphonates
AU4659893A (en) * 1992-06-30 1994-01-24 Research Corporation Technologies, Inc. Trivalent synthesis of oligonucleotides containing stereospecific alkylphosphonates and arylphosphonates
WO1995008556A1 (en) * 1993-09-21 1995-03-30 Amersham International Plc Reagents comprising chimeric molecules of nucleic acids and nucleic acid analogs
US5955597A (en) * 1993-11-16 1999-09-21 Genta, Incorporated Chirally enriched synthetic phosphate oligomers
JP2001508281A (ja) * 1995-11-14 2001-06-26 ベイラー カレッジ オブ メディシン 活性表面化学特性に基づく統合核酸ハイブリダイゼーション装置
US7195871B2 (en) 1996-01-24 2007-03-27 Third Wave Technologies, Inc Methods and compositions for detecting target sequences
US6706471B1 (en) 1996-01-24 2004-03-16 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5985557A (en) 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
US7122364B1 (en) 1998-03-24 2006-10-17 Third Wave Technologies, Inc. FEN endonucleases
US6875572B2 (en) 1996-01-24 2005-04-05 Third Wave Technologies, Inc. Nucleic acid detection assays
DK1634890T3 (da) * 1996-01-24 2009-03-09 Third Wave Tech Inc Invasiv klövning af nukleinsyrer
JP4362150B2 (ja) 1996-11-29 2009-11-11 サード ウェーブ テクノロジーズ，インコーポレーテッド Ｆｅｎ−１エンドヌクレアーゼ、混合物、および開裂方法
US6251591B1 (en) 1997-02-27 2001-06-26 Lorne Park Research, Inc. Quantitative method for detecting nucleotide concentration
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
US8182991B1 (en) 1997-11-26 2012-05-22 Third Wave Technologies, Inc. FEN-1 endonucleases, mixtures and cleavage methods
US6441152B1 (en) 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
DE69938400T2 (de) * 1998-12-08 2009-04-23 Boston Probes, Inc., Bedford Verfahren, Kits und Zusammensetzungen zur Identifizierung von elektrostatisch an Matrizen gebundenen Nukleinsäuren
GB2433505A (en) * 2005-12-20 2007-06-27 Sharp Kk Capture agents for binding a ligand
GB2433506A (en) * 2005-12-20 2007-06-27 Sharp Kk A method of producing a multimeric capture agent
GB2433591A (en) * 2005-12-20 2007-06-27 Sharp Kk Method for functionalising a hydrophobic substrate
SG10201709799SA (en) * 2016-11-29 2018-06-28 Helios Bioelectronics Inc Method for quantitatively profiling nucleic acids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469863A (en) * 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
AU5698186A (en) * 1985-03-15 1986-10-13 Summerton, J. Polynucleotide assay reagent and method
ATE107654T1 (de) * 1987-03-02 1994-07-15 Gen Probe Inc Polykationische träger zur reinigung, trennung und hybridisierung von nukleinsäure.
US5030557A (en) * 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices

Also Published As

Publication number Publication date
EP0411186A1 (de) 1991-02-06
CA1337639C (en) 1995-11-28
EP0411186B1 (de) 1995-10-18
ES2080737T3 (es) 1996-02-16
JP2912385B2 (ja) 1999-06-28
DE68924591D1 (de) 1995-11-23
JPH0383600A (ja) 1991-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee