DE68920264T2 - Verfahren zur Auflösung von Cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-on und deren Maleinsäuresalze. - Google Patents

Verfahren zur Auflösung von Cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-on und deren Maleinsäuresalze.

Info

Publication number
DE68920264T2
DE68920264T2 DE68920264T DE68920264T DE68920264T2 DE 68920264 T2 DE68920264 T2 DE 68920264T2 DE 68920264 T DE68920264 T DE 68920264T DE 68920264 T DE68920264 T DE 68920264T DE 68920264 T2 DE68920264 T2 DE 68920264T2
Authority
DE
Germany
Prior art keywords
cis
malic acid
furyl
amino
eth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68920264T
Other languages
German (de)
English (en)
Other versions
DE68920264D1 (de
Inventor
Brett Dwight Boyer
Thomas Michael Eckrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE68920264D1 publication Critical patent/DE68920264D1/de
Publication of DE68920264T2 publication Critical patent/DE68920264T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68920264T 1988-10-17 1989-10-12 Verfahren zur Auflösung von Cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-on und deren Maleinsäuresalze. Expired - Fee Related DE68920264T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/258,919 US4931556A (en) 1988-10-17 1988-10-17 Method of resolving cis 3-amino-4-(2-(2-furyl)eth-1-yl)-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof

Publications (2)

Publication Number Publication Date
DE68920264D1 DE68920264D1 (de) 1995-02-09
DE68920264T2 true DE68920264T2 (de) 1995-05-24

Family

ID=22982693

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68920264T Expired - Fee Related DE68920264T2 (de) 1988-10-17 1989-10-12 Verfahren zur Auflösung von Cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-on und deren Maleinsäuresalze.

Country Status (11)

Country Link
US (1) US4931556A (https=)
EP (1) EP0365212B1 (https=)
JP (1) JPH02169589A (https=)
KR (1) KR900006323A (https=)
AT (1) ATE116313T1 (https=)
DE (1) DE68920264T2 (https=)
ES (1) ES2065395T3 (https=)
GR (1) GR3015506T3 (https=)
HU (1) HU207312B (https=)
IE (1) IE65410B1 (https=)
IL (1) IL91959A0 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030725A (en) * 1990-02-06 1991-07-09 Eli Lilly And Company Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one using (-)-DAG
US5057607A (en) * 1990-06-08 1991-10-15 Eli Lilly And Company Enantiomerically selective biocatalyzed acylation
IL99380A (en) * 1990-09-13 1997-01-10 Lilly Co Eli Process for the preparation of acid addition salt of 3-amino-4-arylethyl-2-oxoazetidine acetic acid derivatives and n-beta-methyl acrylic acid ester intermediate therefor
US5225553A (en) * 1990-09-13 1993-07-06 Eli Lilly And Company Intermediates to 1-carbacephalosporins and process for preparation thereof
US5159073A (en) * 1990-09-13 1992-10-27 Eli Lilly And Company Intermediates to 1-carbacephalosporins and process for preparation thereof
US5142038A (en) * 1991-07-23 1992-08-25 Eli Lilly And Company Process of enantiomeric separation of carbacephem intermediates
TW372244B (en) * 1993-07-29 1999-10-21 Ciba Sc Holding Ag Process for producing novel finely divided highly transparent diketopyrrolopyrrole pigments
EP0640604B2 (de) * 1993-07-29 2004-06-30 Ciba SC Holding AG Neue feinteilige cyansubstituierte Diketopyrrolopyrrolpigmente und Verwendung derselben
JP3360558B2 (ja) 1997-01-06 2002-12-24 株式会社村田製作所 圧電型電気音響変換器
AU6049000A (en) * 1999-07-23 2001-02-13 Eli Lilly And Company Enantioselective acylation of cis racemic azetidinones
ES2575954T3 (es) 2007-10-11 2016-07-04 The Regents Of The University Of California Composiciones y métodos de inhibición de la amidasa ácida hidrolizante de la N-aciletanolamina
WO2014144836A2 (en) 2013-03-15 2014-09-18 The Regents Of The University Of California Carbamate derivatives of lactam based n-acylethanolamine acid amidase (naaa) inhibitors
WO2014144547A2 (en) 2013-03-15 2014-09-18 The Regents Of The University Of California Amide derivatives of lactam based n-acylethanolamine acid amidase (naaa) inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834736B1 (https=) * 1969-05-14 1973-10-23
FR2229401A1 (en) * 1973-05-17 1974-12-13 Medimac Sa Optical resolution of rotoxamine - using dextro-maleic acid and direct pptn. of the laevo-rotoxamine-dextro-maleate salt useful as an antihistamine
JPS5310974B2 (https=) * 1974-06-10 1978-04-18
US4727146A (en) * 1980-07-03 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Synthesis of chiral 1-benzyl-1,2,3,4-tetra-hydroisoquinolines by asymmetric reduction
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics

Also Published As

Publication number Publication date
GR3015506T3 (en) 1995-06-30
IE893322L (en) 1990-04-17
EP0365212B1 (en) 1994-12-28
ES2065395T3 (es) 1995-02-16
EP0365212A3 (en) 1991-11-06
ATE116313T1 (de) 1995-01-15
HU207312B (en) 1993-03-29
IE65410B1 (en) 1995-10-18
KR900006323A (ko) 1990-05-07
US4931556A (en) 1990-06-05
IL91959A0 (en) 1990-07-12
HU895327D0 (https=) 1990-01-28
EP0365212A2 (en) 1990-04-25
JPH02169589A (ja) 1990-06-29
DE68920264D1 (de) 1995-02-09
HUT58077A (en) 1992-01-28

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8339 Ceased/non-payment of the annual fee