DE69520964T2 - Additionssalze von N-Acylasparaginsäure und Alpha-arylalkylaminen und Verfahren zur optischen Trennung von Alphaarylalkylaminen - Google Patents

Additionssalze von N-Acylasparaginsäure und Alpha-arylalkylaminen und Verfahren zur optischen Trennung von Alphaarylalkylaminen

Info

Publication number
DE69520964T2
DE69520964T2 DE69520964T DE69520964T DE69520964T2 DE 69520964 T2 DE69520964 T2 DE 69520964T2 DE 69520964 T DE69520964 T DE 69520964T DE 69520964 T DE69520964 T DE 69520964T DE 69520964 T2 DE69520964 T2 DE 69520964T2
Authority
DE
Germany
Prior art keywords
alphaarylalkylamines
arylalkylamines
alpha
addition salts
optical separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69520964T
Other languages
English (en)
Other versions
DE69520964D1 (de
Inventor
Toyoto Hijiya
Teruo Yonekawa
Tadashi Takemoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE69520964D1 publication Critical patent/DE69520964D1/de
Application granted granted Critical
Publication of DE69520964T2 publication Critical patent/DE69520964T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82Purification; Separation; Stabilisation; Use of additives
    • C07C209/86Separation
    • C07C209/88Separation of optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/83Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69520964T 1994-06-21 1995-03-20 Additionssalze von N-Acylasparaginsäure und Alpha-arylalkylaminen und Verfahren zur optischen Trennung von Alphaarylalkylaminen Expired - Fee Related DE69520964T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6139112A JPH083120A (ja) 1994-06-21 1994-06-21 アシル−アミノ酸とα−アリールアミンとの付加塩及びα−アリールアミンの光学分割法

Publications (2)

Publication Number Publication Date
DE69520964D1 DE69520964D1 (de) 2001-06-21
DE69520964T2 true DE69520964T2 (de) 2002-01-17

Family

ID=15237774

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69520964T Expired - Fee Related DE69520964T2 (de) 1994-06-21 1995-03-20 Additionssalze von N-Acylasparaginsäure und Alpha-arylalkylaminen und Verfahren zur optischen Trennung von Alphaarylalkylaminen
DE69510128T Expired - Fee Related DE69510128T2 (de) 1994-06-21 1995-03-20 Additionssalze von Acylaminosäuren und Alpha-arylaminen und Verfahren zur optischen Trennung von Alphaarylaminen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69510128T Expired - Fee Related DE69510128T2 (de) 1994-06-21 1995-03-20 Additionssalze von Acylaminosäuren und Alpha-arylaminen und Verfahren zur optischen Trennung von Alphaarylaminen

Country Status (5)

Country Link
US (1) US5629450A (de)
EP (2) EP0688760B1 (de)
JP (1) JPH083120A (de)
CA (1) CA2148172A1 (de)
DE (2) DE69520964T2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08333388A (ja) * 1995-06-12 1996-12-17 Ajinomoto Co Inc 新規アスパルチルジペプチドアミド誘導体及び甘味剤
JP3665976B2 (ja) * 1995-06-29 2005-06-29 東レ・ファインケミカル株式会社 光学分割剤およびそれを用いた光学活性N−tert−ブチル−2−ピペラジンカルボキシアミドの製造法
JPH09208546A (ja) * 1995-11-29 1997-08-12 Ajinomoto Co Inc 新規置換ベンジルアミンの付加塩及びその光学分割法
US6342636B1 (en) * 1997-11-06 2002-01-29 Yamakawa Chemical Industry Co., Ltd. Process for preparing optically active amines and optically active carboxylic acids, and intermediates for preparation
DE10205828A1 (de) 2002-02-13 2003-08-21 Corovin Gmbh Composite mit absorbierender Lage
FR2870537A1 (fr) 2004-05-19 2005-11-25 Servier Lab Nouveau procede de synthese du (1s)-4,5-dimethoxy-1-(methyl aminomethyl-)-benzocyclobutane et de ses sels d'addition, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
DE102007036187A1 (de) * 2007-08-02 2008-06-19 Clariant International Limited Alkoxylierte Phosphorsäuretriester mit hohem Alkoxylierungsgrad
FR2927900B1 (fr) * 2008-02-27 2010-09-17 Clariant Specialty Fine Chem Procede de preparation d'alpha-aminoacetals optiquement actifs.
CN104860830B (zh) * 2015-04-08 2017-07-11 东北制药集团股份有限公司 一种右旋苯乙胺盐及右旋苯乙胺的制备方法
CN107417546A (zh) * 2017-06-20 2017-12-01 荆楚理工学院 一种具有光学活性的α‑甲基苄胺的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3028430A (en) * 1955-03-28 1962-04-03 Parke Davis & Co Process for the production of optically active isomers of amphetamine
JP3304419B2 (ja) * 1992-09-30 2002-07-22 東レ株式会社 光学活性1−(4−ハロゲノフェニル)エチルアミンの製造法

Also Published As

Publication number Publication date
EP0688760B1 (de) 1999-06-09
DE69510128D1 (de) 1999-07-15
JPH083120A (ja) 1996-01-09
DE69510128T2 (de) 2000-02-03
US5629450A (en) 1997-05-13
DE69520964D1 (de) 2001-06-21
EP0845455A1 (de) 1998-06-03
EP0688760A1 (de) 1995-12-27
EP0845455B1 (de) 2001-05-16
CA2148172A1 (en) 1995-12-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee