DE68918003D1 - Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung. - Google Patents

Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung.

Info

Publication number
DE68918003D1
DE68918003D1 DE68918003T DE68918003T DE68918003D1 DE 68918003 D1 DE68918003 D1 DE 68918003D1 DE 68918003 T DE68918003 T DE 68918003T DE 68918003 T DE68918003 T DE 68918003T DE 68918003 D1 DE68918003 D1 DE 68918003D1
Authority
DE
Germany
Prior art keywords
compounds
preparation
chem
alkyl
imidazoquinoxaline compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68918003T
Other languages
English (en)
Other versions
DE68918003T2 (de
Inventor
Holger Claus Hansen
Frank Watjen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE68918003D1 publication Critical patent/DE68918003D1/de
Application granted granted Critical
Publication of DE68918003T2 publication Critical patent/DE68918003T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
DE68918003T 1988-06-14 1989-06-07 Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung. Expired - Fee Related DE68918003T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK322088A DK161148C (da) 1988-06-14 1988-06-14 Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne

Publications (2)

Publication Number Publication Date
DE68918003D1 true DE68918003D1 (de) 1994-10-13
DE68918003T2 DE68918003T2 (de) 1995-01-05

Family

ID=8120424

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68918003T Expired - Fee Related DE68918003T2 (de) 1988-06-14 1989-06-07 Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung.

Country Status (18)

Country Link
US (1) US5034530A (de)
EP (1) EP0347094B1 (de)
JP (1) JPH0236184A (de)
KR (1) KR910000665A (de)
AT (1) ATE111100T1 (de)
AU (1) AU618366B2 (de)
CA (1) CA1327798C (de)
DE (1) DE68918003T2 (de)
DK (1) DK161148C (de)
ES (1) ES2060769T3 (de)
FI (1) FI92204C (de)
IE (1) IE69963B1 (de)
IL (1) IL90543A0 (de)
NO (1) NO170806C (de)
NZ (1) NZ229499A (de)
PH (1) PH26337A (de)
PT (1) PT90865B (de)
ZA (1) ZA894430B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160876C (da) * 1987-12-08 1991-10-14 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
US5276028A (en) * 1990-06-22 1994-01-04 Nordisk A/S Imidazoquinoxaline compounds
DK151890D0 (da) * 1990-06-22 1990-06-22 Ferrosan As Heterocykliske forbindelser deres fremstilling og brug
US5371080A (en) * 1990-06-22 1994-12-06 Novo Nordisk A/S Imidazoquinazoline compounds and their use
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
JP3147902B2 (ja) * 1991-06-14 2001-03-19 ファルマシア・アンド・アップジョン・カンパニー イミダゾ〔１，５−ａ〕キノキサリン
US6635626B1 (en) * 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
US6235740B1 (en) 1997-08-25 2001-05-22 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
DE69940808D1 (de) * 1998-03-04 2009-06-10 Bristol Myers Squibb Co Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren
US20040180898A1 (en) * 2003-03-03 2004-09-16 Bang-Chi Chen Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
AU2008329072A1 (en) * 2007-11-30 2009-06-04 Elbion Gmbh Aryl and heteroaryl fused imidazo (1,5-A) pyrazines as inhibitors of phosphodiesterase 10
CN101918408A (zh) * 2007-11-30 2010-12-15 惠氏有限责任公司 作为磷酸二酯酶10的抑制剂的芳基和杂芳基稠合的咪唑并[1,5-a]吡嗪
TW201111383A (en) * 2009-05-29 2011-04-01 Wyeth Llc Substituted imidazo[1,5-a]quinoxalines as inhibitors of phosphodiesterase 10

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440929A (en) * 1981-07-16 1984-04-03 Usv Pharmaceutical Corporation Imidazoquinoxaline compounds
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DE3668116D1 (de) * 1985-10-19 1990-02-15 Beecham Group Plc Zusammensetzung zur behandlung von infektionen.
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
FI892908A (fi) 1989-12-15
EP0347094B1 (de) 1994-09-07
FI892908A0 (fi) 1989-06-14
AU3624489A (en) 1989-12-21
JPH0236184A (ja) 1990-02-06
AU618366B2 (en) 1991-12-19
ZA894430B (en) 1990-02-28
CA1327798C (en) 1994-03-15
ES2060769T3 (es) 1994-12-01
DK322088A (da) 1990-03-27
DE68918003T2 (de) 1995-01-05
NO170806C (no) 1992-12-09
DK161148C (da) 1991-11-18
NZ229499A (en) 1991-04-26
PT90865B (pt) 1994-11-30
ATE111100T1 (de) 1994-09-15
PT90865A (pt) 1989-12-29
PH26337A (en) 1992-04-29
NO892456D0 (no) 1989-06-13
FI92204C (fi) 1994-10-10
US5034530A (en) 1991-07-23
IE891892L (en) 1989-12-14
FI92204B (fi) 1994-06-30
NO170806B (no) 1992-08-31
EP0347094A1 (de) 1989-12-20
IL90543A0 (en) 1990-01-18
NO892456L (no) 1989-12-15
KR910000665A (ko) 1991-01-30
DK322088D0 (da) 1988-06-14
IE69963B1 (en) 1996-10-16
DK161148B (da) 1991-06-03

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Publication Publication Date Title
DE3850861T2 (de) Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung.
DE68918003D1 (de) Imidazochinoxalinverbindungen und ihre Herstellung und Verwendung.
ATE80392T1 (de) Oxadiazolylacetonitrile, ihre herstellung und anwendung.
EP0311321A3 (en) Heterocyclic compounds and their preparation and use
DE69029910T2 (de) Imidazoquinoxalinverbindungen, deren herstellung und verwendung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN

8339 Ceased/non-payment of the annual fee