DE68917762D1 - Herstellung von alpha-1-Aspartyl-1-phenylalanin-methylester mit geschütztem Stickstoffatom. - Google Patents

Herstellung von alpha-1-Aspartyl-1-phenylalanin-methylester mit geschütztem Stickstoffatom.

Info

Publication number
DE68917762D1
DE68917762D1 DE68917762T DE68917762T DE68917762D1 DE 68917762 D1 DE68917762 D1 DE 68917762D1 DE 68917762 T DE68917762 T DE 68917762T DE 68917762 T DE68917762 T DE 68917762T DE 68917762 D1 DE68917762 D1 DE 68917762D1
Authority
DE
Germany
Prior art keywords
methyl ester
aspartyl
phenylalanine methyl
alpha
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68917762T
Other languages
English (en)
Other versions
DE68917762T2 (de
Inventor
Toshio Katoh
Chojiro Higuchi
Takeshi Oura
Masanobu - Ajioka
Akihiro Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63065920A external-priority patent/JP2647420B2/ja
Priority claimed from JP11040388A external-priority patent/JP2688210B2/ja
Priority claimed from JP63110417A external-priority patent/JP2698372B2/ja
Priority claimed from JP63143674A external-priority patent/JP2647439B2/ja
Priority claimed from JP16259388A external-priority patent/JP2598467B2/ja
Priority claimed from JP16978288A external-priority patent/JP2688213B2/ja
Priority claimed from JP16978388A external-priority patent/JP2688214B2/ja
Priority claimed from JP63180358A external-priority patent/JP2598470B2/ja
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Publication of DE68917762D1 publication Critical patent/DE68917762D1/de
Application granted granted Critical
Publication of DE68917762T2 publication Critical patent/DE68917762T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE68917762T 1988-03-22 1989-03-16 Herstellung von alpha-1-Aspartyl-1-phenylalanin-methylester mit geschütztem Stickstoffatom. Expired - Fee Related DE68917762T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP63065920A JP2647420B2 (ja) 1988-03-22 1988-03-22 N−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法
JP11040388A JP2688210B2 (ja) 1988-05-09 1988-05-09 N−保護アスパラギン酸無水物の製造法
JP63110417A JP2698372B2 (ja) 1988-05-09 1988-05-09 N−保護アスパラギン酸無水物の製造方法
JP63143674A JP2647439B2 (ja) 1988-06-13 1988-06-13 N−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法
JP16259388A JP2598467B2 (ja) 1988-07-01 1988-07-01 N−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法
JP16978288A JP2688213B2 (ja) 1988-07-07 1988-07-07 N−カルボベンゾキシ−l−アスパラギン酸無水物の製造法
JP16978388A JP2688214B2 (ja) 1988-07-07 1988-07-07 N−カルボベンゾキシ−l−アスパラギン酸無水物の製造方法
JP63180358A JP2598470B2 (ja) 1988-07-21 1988-07-21 N−ベンジルオキシカルボニル―αーL―アスパルチル―L―フェニルアラニンメチルエステルの製造方法

Publications (2)

Publication Number Publication Date
DE68917762D1 true DE68917762D1 (de) 1994-10-06
DE68917762T2 DE68917762T2 (de) 1995-04-13

Family

ID=27572581

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917762T Expired - Fee Related DE68917762T2 (de) 1988-03-22 1989-03-16 Herstellung von alpha-1-Aspartyl-1-phenylalanin-methylester mit geschütztem Stickstoffatom.

Country Status (9)

Country Link
EP (1) EP0334236B1 (de)
KR (1) KR910006287B1 (de)
AT (1) ATE110740T1 (de)
AU (1) AU605968B2 (de)
BR (1) BR8901324A (de)
CA (1) CA1339658C (de)
DE (1) DE68917762T2 (de)
DK (1) DK141289A (de)
NO (1) NO891243L (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
KR100255843B1 (ko) * 1997-08-07 2000-05-01 허진호 회전형 씨디피

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester

Also Published As

Publication number Publication date
KR890014576A (ko) 1989-10-24
KR910006287B1 (ko) 1991-08-19
EP0334236B1 (de) 1994-08-31
DK141289D0 (da) 1989-03-22
NO891243D0 (no) 1989-03-21
BR8901324A (pt) 1989-11-07
DE68917762T2 (de) 1995-04-13
ATE110740T1 (de) 1994-09-15
NO891243L (no) 1989-09-25
CA1339658C (en) 1998-02-03
DK141289A (da) 1989-09-23
EP0334236A3 (de) 1991-03-20
EP0334236A2 (de) 1989-09-27
AU3162089A (en) 1989-09-28
AU605968B2 (en) 1991-01-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MITSUI CHEMICALS, INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee