DE68900106D1 - Verfahren zur bestimmung der freien ligandenfraktion einer biologischen fluessigkeit. - Google Patents

Verfahren zur bestimmung der freien ligandenfraktion einer biologischen fluessigkeit.

Info

Publication number
DE68900106D1
DE68900106D1 DE8989300062T DE68900106T DE68900106D1 DE 68900106 D1 DE68900106 D1 DE 68900106D1 DE 8989300062 T DE8989300062 T DE 8989300062T DE 68900106 T DE68900106 T DE 68900106T DE 68900106 D1 DE68900106 D1 DE 68900106D1
Authority
DE
Germany
Prior art keywords
ligand
antibody
determining
analogue
free ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989300062T
Other languages
English (en)
Inventor
John Edward Maurice Midgley
Christopher Peter Sheehan
Nicos Demetriou Christofides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27516786&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68900106(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham International PLC filed Critical Amersham International PLC
Application granted granted Critical
Publication of DE68900106D1 publication Critical patent/DE68900106D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8989300062T 1988-01-08 1989-01-05 Verfahren zur bestimmung der freien ligandenfraktion einer biologischen fluessigkeit. Expired - Lifetime DE68900106D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB888800419A GB8800419D0 (en) 1988-01-08 1988-01-08 Method for measuring free fraction of ligands in biological fluids
US47396490A 1990-04-17 1990-04-17
US55158090A 1990-07-02 1990-07-02
US88507092A 1992-05-18 1992-05-18
US08/022,416 US5278080A (en) 1988-01-08 1993-02-11 Method for measuring the free fraction of ligands in biological fluids

Publications (1)

Publication Number Publication Date
DE68900106D1 true DE68900106D1 (de) 1991-07-18

Family

ID=27516786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989300062T Expired - Lifetime DE68900106D1 (de) 1988-01-08 1989-01-05 Verfahren zur bestimmung der freien ligandenfraktion einer biologischen fluessigkeit.

Country Status (12)

Country Link
US (1) US5278080A (de)
EP (1) EP0324540B2 (de)
JP (1) JP2718229B2 (de)
AT (1) ATE64469T1 (de)
AU (1) AU619712B2 (de)
CA (1) CA1340536C (de)
DE (1) DE68900106D1 (de)
ES (1) ES2029114T5 (de)
FI (1) FI92884C (de)
GB (1) GB8800419D0 (de)
WO (1) WO1989006363A1 (de)
ZA (1) ZA8918B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3626468A1 (de) * 1986-08-05 1988-02-11 Hoechst Ag Verfahren und testkit zur bestimmung freier wirkstoffe in biologischen fluessigkeiten
DE3727238A1 (de) * 1987-08-14 1989-02-23 Henning Berlin Gmbh Immunologisches bestimmungsverfahren zur bestimmung von hapteneigenschaften aufweisenden freien substanzen
US5364796A (en) * 1989-07-11 1994-11-15 Pb Diagnostics Systems, Inc. Diagnostic assay system
IT1254858B (it) * 1992-04-14 1995-10-11 Metodo per la determinazione della frazione libera di sostanze presenti nei fluidi biologici.
DE4214922C2 (de) * 1992-05-06 1996-06-13 Brahms Diagnostica Gmbh Verfahren zur quantitativen Bestimmung des Anteils der freien Form eines Schilddrüsenhormon-Liganden in einer biologischen Flüssigkeit und Kit zur Durchführung eines solchen Verfahrens
EP0606950A3 (de) * 1993-01-13 1995-07-12 Eastman Kodak Co Verfahren zur Reaktionsgeschwindigkeitsmessung von Analyten.
WO1996016332A1 (en) * 1994-11-24 1996-05-30 Unipath Limited Recovery of and uses of specific binding agents
DE19504198A1 (de) * 1995-02-09 1996-08-14 Behringwerke Ag Kompetitiver Immuntest unter Verwendung komplexierter Analytderivate
US5888835A (en) * 1996-05-10 1999-03-30 Chiron Diagnostics Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US6143578A (en) * 1996-05-10 2000-11-07 Bayer Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
CA2231569A1 (en) * 1996-07-18 1998-01-29 Behringwerke Aktiengesellschaft Reagents for assays for mycophenolic acid
US6087088A (en) * 1997-01-31 2000-07-11 Bayer Corporation Binding assays using more than one label for determining analyte in the presence of interfering factors
US8900882B2 (en) * 2008-07-31 2014-12-02 Nitto Boseki Co., Ltd. Method of assaying complex and kit to be used therefor
JP5997446B2 (ja) 2011-02-03 2016-09-28 アークレイ株式会社 甲状腺ホルモン固定化担体の液体試薬およびその用途
CN114544831B (zh) * 2022-02-21 2024-05-10 成都翼泰生物科技有限公司 分离血液中游离甲状腺激素的方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292296A (en) * 1978-09-12 1981-09-29 Baxter Travenol Laboratories, Inc. Diagnostic method
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids
JPH0616046B2 (ja) * 1982-03-19 1994-03-02 エキンズ，ロジャー フィリップ 遊離リガンドアッセイ方法およびキット
EP0089806B1 (de) * 1982-03-22 1989-06-28 AMERSHAM INTERNATIONAL plc Bestimmung des freien Anteils von Substanzen in biologischen Flüssigkeiten
ZA837119B (en) * 1982-10-07 1984-12-24 Amersham Int Plc Assay for the free portion of substances in biological fluids
GB2134806B (en) 1983-02-07 1986-07-16 English Clays Lovering Pochin A tube pressure filter
GB8408193D0 (en) * 1984-03-30 1984-05-10 Cambridge Patent Dev Antibodies
DE3727238A1 (de) * 1987-08-14 1989-02-23 Henning Berlin Gmbh Immunologisches bestimmungsverfahren zur bestimmung von hapteneigenschaften aufweisenden freien substanzen

Also Published As

Publication number Publication date
ATE64469T1 (de) 1991-06-15
EP0324540B1 (de) 1991-06-12
FI903348A0 (fi) 1990-07-03
EP0324540A1 (de) 1989-07-19
ZA8918B (en) 1989-10-25
AU2925189A (en) 1989-08-01
US5278080A (en) 1994-01-11
ES2029114T5 (es) 2001-04-16
AU619712B2 (en) 1992-01-30
JPH03502243A (ja) 1991-05-23
CA1340536C (en) 1999-05-11
FI92884C (fi) 1995-01-10
JP2718229B2 (ja) 1998-02-25
EP0324540B2 (de) 2000-12-27
ES2029114T3 (es) 1992-07-16
GB8800419D0 (en) 1988-02-10
WO1989006363A1 (en) 1989-07-13
FI92884B (fi) 1994-09-30

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings