DE650396T1 - Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse. - Google Patents
Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse.Info
- Publication number
- DE650396T1 DE650396T1 DE0650396T DE94915227T DE650396T1 DE 650396 T1 DE650396 T1 DE 650396T1 DE 0650396 T DE0650396 T DE 0650396T DE 94915227 T DE94915227 T DE 94915227T DE 650396 T1 DE650396 T1 DE 650396T1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- biochemical processes
- detecting cellular
- sec
- cellular processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/20—Material Coatings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93303806 | 1993-05-17 | ||
PCT/GB1994/001040 WO1994026413A1 (en) | 1993-05-17 | 1994-05-16 | Devices and methods for the measurement of cellular biochemical processes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE650396T1 true DE650396T1 (de) | 1995-11-30 |
Family
ID=8214414
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69407923T Expired - Lifetime DE69407923T2 (de) | 1993-05-17 | 1994-05-16 | Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse |
DE0650396T Pending DE650396T1 (de) | 1993-05-17 | 1994-05-16 | Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69407923T Expired - Lifetime DE69407923T2 (de) | 1993-05-17 | 1994-05-16 | Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse |
Country Status (10)
Country | Link |
---|---|
US (2) | US5665562A (de) |
EP (1) | EP0650396B1 (de) |
JP (1) | JP3152933B2 (de) |
AT (1) | ATE162216T1 (de) |
CA (1) | CA2139409C (de) |
DE (2) | DE69407923T2 (de) |
DK (1) | DK0650396T3 (de) |
ES (1) | ES2072847T3 (de) |
FI (1) | FI110488B (de) |
WO (1) | WO1994026413A1 (de) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0716635B2 (ja) * | 1993-01-27 | 1995-03-01 | 旭サナック株式会社 | 建築用塗材吹付機 |
JP3152933B2 (ja) * | 1993-05-17 | 2001-04-03 | アマーシャム・インターナショナル・ピーエルシー | 細胞生化学プロセスを測定するための装置および方法 |
JP3315269B2 (ja) * | 1994-10-07 | 2002-08-19 | アロカ株式会社 | 放射性試料測定用プレート |
US5792426A (en) * | 1994-10-11 | 1998-08-11 | Schweizerische Eidgenossenschaft Vertreten Durch Das Ac-Laboratorium Spiez Der Gruppe Rustung | Multi-well titerplate for instrumental analysis |
CN1181720A (zh) * | 1995-04-25 | 1998-05-13 | 伊萝莉公司 | 可远程编程的存储器材料及其应用 |
US5961923A (en) * | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
US5925562A (en) * | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
JP3118528B2 (ja) | 1996-01-26 | 2000-12-18 | 東邦レーヨン株式会社 | ステアリングホイールおよびその製造方法 |
US5739001A (en) * | 1996-10-29 | 1998-04-14 | E. I. Du Pont De Nemours And Company | Solid phase cell-based assay |
GB2319836B (en) * | 1996-11-25 | 2001-04-04 | Porvair Plc | Microplates |
DE69831522T2 (de) | 1997-03-03 | 2006-06-14 | Amersham Biosciences Uk Ltd | In-situ Zellextraktion und Assay-Verfahren |
DE19712484C2 (de) * | 1997-03-25 | 1999-07-08 | Greiner Gmbh | Microplatte mit transparentem Boden und Verfahren zu deren Herstellung |
ATE224770T1 (de) | 1997-05-02 | 2002-10-15 | Gen Probe Inc | Reaktion behälter apparat |
US5910403A (en) * | 1997-05-15 | 1999-06-08 | The Regents Of University Of California | Methods for measuring cellular proliferation and destruction rates in vitro and in vivo |
JP3719932B2 (ja) * | 1997-08-18 | 2005-11-24 | アメルシャム・パブリック・リミテッド・カンパニー | シンチレーションプロキシミティー試験 |
US6077669A (en) * | 1997-11-04 | 2000-06-20 | Becton Dickinson And Company | Kit and method for fluorescence based detection assay |
CA2306879C (en) | 1997-11-14 | 2007-10-16 | Gen-Probe Incorporated | Assay work station |
US6066446A (en) * | 1997-12-19 | 2000-05-23 | Nen Life Science Products, Inc. | Assay member and method for its manufacture |
US6977141B2 (en) | 1998-02-10 | 2005-12-20 | Vicuron Pharmaceuticals Inc. | Direct adsorption scintillation assay for measuring enzyme activity and assaying biochemical processes |
US6388788B1 (en) | 1998-03-16 | 2002-05-14 | Praelux, Inc. | Method and apparatus for screening chemical compounds |
US20030036855A1 (en) * | 1998-03-16 | 2003-02-20 | Praelux Incorporated, A Corporation Of New Jersey | Method and apparatus for screening chemical compounds |
US6463647B1 (en) * | 1998-03-18 | 2002-10-15 | Corning Incorporated | Method of making an extruded high density assay plate |
DE59903746D1 (de) * | 1998-03-27 | 2003-01-23 | Aventis Pharma Gmbh | Miniaturisierte mikrotiterplatte für hochdurchsatz-screening |
GB9808836D0 (en) * | 1998-04-27 | 1998-06-24 | Amersham Pharm Biotech Uk Ltd | Microfabricated apparatus for cell based assays |
EP1076719A1 (de) | 1998-05-15 | 2001-02-21 | AstraZeneca AB | Ein scintillationsannäherungsversuchsaufbau zur bestimmung von peptidoglykansynthese |
DE19822827A1 (de) * | 1998-05-20 | 2001-01-18 | Forschungszentrum Juelich Gmbh | Verfahren zur Durchführung einer Messung der Interaktion von Chemikalien mit Zellen |
US6057092A (en) * | 1998-08-31 | 2000-05-02 | Trellis Bioinformatics, Inc. | Cellular transport detection method |
GB2342350A (en) * | 1998-10-05 | 2000-04-12 | Univ Nottingham Trent | Solid supports containing oxazole scintillants |
WO2001067103A1 (en) * | 2000-03-06 | 2001-09-13 | Bioseek, Inc. | Function homology screening |
DE60143703D1 (de) * | 2000-04-19 | 2011-02-03 | Corning Inc | Mehrfachlochplatte und ihr herstellungsverfahren |
US7347977B2 (en) * | 2000-06-08 | 2008-03-25 | Eppendorf Ag | Microtitration plate |
JP4282251B2 (ja) | 2000-08-02 | 2009-06-17 | 富士フイルム株式会社 | 生化学解析用ユニットおよびそれを用いた生化学解析方法 |
GB0027516D0 (en) * | 2000-11-10 | 2000-12-27 | Amersham Pharm Biotech Uk Ltd | Support and method for cell based assays |
EP1343973B2 (de) * | 2000-11-16 | 2020-09-16 | California Institute Of Technology | Vorrichtung und verfahren zur durchführung von assays und screening mit hohem durchsatz |
EP1346230B1 (de) * | 2000-12-26 | 2006-04-12 | Cerenis | Auf tsap6-bindungspartnern beruhendes screeningverfahren |
DE10108892B4 (de) * | 2001-02-23 | 2005-08-18 | Graffinity Pharmaceuticals Ag | Synthesevorrichtung und Verfahren zu deren Herstellung |
US20030064508A1 (en) * | 2001-09-20 | 2003-04-03 | 3-Dimensional Pharmaceuticals, Inc. | Conductive microtiter plate |
IL161498A0 (en) | 2001-10-24 | 2004-09-27 | Univ California | Measurement of protein synthesis rates in humans and experimental system by use of isotopically labeled water |
WO2003068919A2 (en) * | 2002-02-12 | 2003-08-21 | The Regents Of The University Of California | Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation |
US20030183958A1 (en) * | 2002-03-28 | 2003-10-02 | Becton, Dickinson And Company | Multi-well plate fabrication |
US20030224420A1 (en) * | 2002-04-05 | 2003-12-04 | Hellerstein Marc K. | Method for isolating and measuring proliferation of long-term label retaining cells and stem cells |
WO2003089139A1 (en) * | 2002-04-15 | 2003-10-30 | Cool Options, Inc. | Thermally-conductive biological assay trays |
ATE418619T1 (de) * | 2002-06-14 | 2009-01-15 | Pierce Biotechnology Inc | Homogenes assay zum nachweis von enzymaktivität |
DE60329500D1 (de) * | 2002-07-12 | 2009-11-12 | Morehouse School Of Medicine | Verfahren zur identifikation von salzempfindlichen personen |
US20060094057A1 (en) * | 2002-07-30 | 2006-05-04 | Maro K. Hellerstein | Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry |
WO2004021863A2 (en) * | 2002-09-04 | 2004-03-18 | The Regents Of The University Of California | Methods for measuring rates of replication and death of nfectious microbial agents in an infected host organism |
CA2498378C (en) * | 2002-09-13 | 2013-12-17 | The Regents Of The University Of California | Methods for measuring rates of reverse cholesterol transport in vivo, as an index of anti-atherogenesis |
US20070248540A1 (en) * | 2002-09-16 | 2007-10-25 | The Regents Of The University Of California | Biochemical methods for measuring metabolic fitness of tissues or whole organisms |
US7504233B2 (en) * | 2002-11-04 | 2009-03-17 | The Regents Of The University Of California | Methods for determining the metabolism of sugars and fats in an individual |
US20050202406A1 (en) | 2003-11-25 | 2005-09-15 | The Regents Of The University Of California | Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems |
TW200538738A (en) | 2004-02-20 | 2005-12-01 | Univ California | Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity |
EP1723252A4 (de) * | 2004-03-11 | 2009-07-29 | Univ California | Zeitliche und räumliche charakterisierung biosynthetischer ereignisse in lebenden organismen durch isotopen-fingerprinting unter bedingungen auferlegter isotopengradienten |
US20050238577A1 (en) * | 2004-03-29 | 2005-10-27 | The Regents Of The University Of California | Isolation of epithelial cells or their biochemical contents from excreta after in vivo isotopic labeling |
US20060251576A1 (en) * | 2005-05-03 | 2006-11-09 | The Regents Of The University Of California | Methods for measuring cholesterol metabolism and transport |
TW200711660A (en) * | 2005-06-10 | 2007-04-01 | Univ California | Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development |
DK1750155T3 (da) * | 2005-08-01 | 2013-01-07 | Ibidi Gmbh | Fremgangsmåde til fremstilling af et prøvekammer |
DE602006009220D1 (de) * | 2005-12-09 | 2009-10-29 | Hoffmann La Roche | Scintillation Proximity Assay |
US20130122580A1 (en) * | 2010-01-08 | 2013-05-16 | Sumitomo Bakelite Co., Ltd. | Culture vessel for forming aggregated cell mass |
US20140242600A1 (en) * | 2011-06-08 | 2014-08-28 | The Board Of Trustees Of The Leland Stanford Junior University | Imaging the heterogeneous uptake of radiolabeled molecules in single living cells |
WO2013036885A1 (en) | 2011-09-08 | 2013-03-14 | The Regents Of The University Of California | Metabolic flux measurement, imaging and microscopy |
EP2788772B1 (de) | 2011-12-07 | 2018-02-14 | GlaxoSmithKline LLC | Verfahren zur bestimmung der gesamtkörperskelettmuskelmasse |
US9134319B2 (en) | 2013-03-15 | 2015-09-15 | The Regents Of The University Of California | Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo |
US9790465B2 (en) * | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
BR112016018978B1 (pt) * | 2014-02-18 | 2024-03-12 | Takeda Pharmaceutical Company Limited | Método para medir atividade enzimática lisossomal |
SG11201703500XA (en) | 2014-10-29 | 2017-05-30 | Corning Inc | Perfusion bioreactor platform |
EP3212759A1 (de) | 2014-10-29 | 2017-09-06 | Corning Incorporated | Zellkultureinsatz |
MX2019010115A (es) | 2017-02-27 | 2019-11-21 | Westrock Mwv Llc | Carton de barrera sellable termicamente. |
WO2019014610A1 (en) | 2017-07-14 | 2019-01-17 | Corning Incorporated | CELL CULTURE CONTAINER FOR 3D CULTURE AND METHODS OF CULTURING 3D CELLS |
JP7245222B2 (ja) | 2017-07-14 | 2023-03-23 | コーニング インコーポレイテッド | 手動又は自動で培地を交換するための3d細胞培養容器 |
JP7197557B2 (ja) | 2017-07-14 | 2022-12-27 | コーニング インコーポレイテッド | 多孔性支持体を有する細胞培養槽 |
US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
PL3649229T3 (pl) | 2018-07-13 | 2021-12-06 | Corning Incorporated | Naczynia do hodowli komórkowych ze stabilizującymi urządzeniami |
US11912968B2 (en) | 2018-07-13 | 2024-02-27 | Corning Incorporated | Microcavity dishes with sidewall including liquid medium delivery surface |
US11661574B2 (en) | 2018-07-13 | 2023-05-30 | Corning Incorporated | Fluidic devices including microplates with interconnected wells |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4000252A (en) * | 1974-01-04 | 1976-12-28 | Kenneth Kosak | Immunoscintillation cell |
US4382074A (en) * | 1978-03-27 | 1983-05-03 | Hiram Hart | Scintillation proximity assay |
ES8501998A1 (es) * | 1982-10-12 | 1984-12-16 | Dynatech Lab | Un recipiente que tiene al menos una cavidad o pocillo para contener al menos una muestra de ensayo durante una medicion fluometrica. |
US4588698A (en) * | 1982-10-19 | 1986-05-13 | University Patents, Inc. | Encapsulated scintillators for measuring the concentration of tritiated solutes |
US4568649A (en) * | 1983-02-22 | 1986-02-04 | Immunex Corporation | Immediate ligand detection assay |
SE8803602D0 (sv) * | 1988-10-11 | 1988-10-11 | Wallac Oy | A sample plate with a plurality of sample wells or vials intended for radiolabeled binding assays |
JPH04335154A (ja) * | 1991-05-09 | 1992-11-24 | S R L:Kk | 薬物スクリ−ニング方法 |
DK0576090T3 (da) * | 1992-06-22 | 2001-11-12 | Packard Instr Bv | Klæbende plastscintillator |
JP3152933B2 (ja) * | 1993-05-17 | 2001-04-03 | アマーシャム・インターナショナル・ピーエルシー | 細胞生化学プロセスを測定するための装置および方法 |
-
1994
- 1994-05-16 JP JP52517394A patent/JP3152933B2/ja not_active Expired - Fee Related
- 1994-05-16 AT AT94915227T patent/ATE162216T1/de not_active IP Right Cessation
- 1994-05-16 ES ES94915227T patent/ES2072847T3/es not_active Expired - Lifetime
- 1994-05-16 CA CA002139409A patent/CA2139409C/en not_active Expired - Lifetime
- 1994-05-16 US US08/373,316 patent/US5665562A/en not_active Expired - Lifetime
- 1994-05-16 DE DE69407923T patent/DE69407923T2/de not_active Expired - Lifetime
- 1994-05-16 EP EP94915227A patent/EP0650396B1/de not_active Expired - Lifetime
- 1994-05-16 DK DK94915227T patent/DK0650396T3/da active
- 1994-05-16 WO PCT/GB1994/001040 patent/WO1994026413A1/en active IP Right Grant
- 1994-05-16 DE DE0650396T patent/DE650396T1/de active Pending
-
1995
- 1995-01-13 FI FI950154A patent/FI110488B/fi active
-
1996
- 1996-11-01 US US08/742,497 patent/US5989854A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE162216T1 (de) | 1998-01-15 |
CA2139409C (en) | 2005-01-04 |
WO1994026413A1 (en) | 1994-11-24 |
DE69407923T2 (de) | 1998-04-30 |
EP0650396A1 (de) | 1995-05-03 |
ES2072847T3 (es) | 1998-03-01 |
JP3152933B2 (ja) | 2001-04-03 |
FI950154A (fi) | 1995-01-13 |
CA2139409A1 (en) | 1994-11-24 |
JPH07509405A (ja) | 1995-10-19 |
FI950154A0 (fi) | 1995-01-13 |
US5989854A (en) | 1999-11-23 |
DK0650396T3 (da) | 1998-09-14 |
FI110488B (fi) | 2003-02-14 |
ES2072847T1 (es) | 1995-08-01 |
US5665562A (en) | 1997-09-09 |
EP0650396B1 (de) | 1998-01-14 |
DE69407923D1 (de) | 1998-02-19 |
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