DE60333370D1 - Zur bildung von partikeln fähiges hbv-precore-protein - Google Patents
Zur bildung von partikeln fähiges hbv-precore-proteinInfo
- Publication number
- DE60333370D1 DE60333370D1 DE60333370T DE60333370T DE60333370D1 DE 60333370 D1 DE60333370 D1 DE 60333370D1 DE 60333370 T DE60333370 T DE 60333370T DE 60333370 T DE60333370 T DE 60333370T DE 60333370 D1 DE60333370 D1 DE 60333370D1
- Authority
- DE
- Germany
- Prior art keywords
- precore protein
- hbv precore
- particles
- hbv
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10123—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002261666 | 2002-09-06 | ||
PCT/JP2003/011389 WO2004022585A1 (ja) | 2002-09-06 | 2003-09-05 | 粒子形成能を有するhbvプレコア蛋白質 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60333370D1 true DE60333370D1 (de) | 2010-08-26 |
Family
ID=31973137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60333370T Expired - Lifetime DE60333370D1 (de) | 2002-09-06 | 2003-09-05 | Zur bildung von partikeln fähiges hbv-precore-protein |
Country Status (12)
Country | Link |
---|---|
US (2) | US7713532B2 (de) |
EP (1) | EP1535927B1 (de) |
JP (1) | JP4459054B2 (de) |
KR (1) | KR101093783B1 (de) |
CN (1) | CN100547001C (de) |
AT (1) | ATE473997T1 (de) |
AU (1) | AU2003261977A1 (de) |
CA (1) | CA2497972C (de) |
DE (1) | DE60333370D1 (de) |
ES (1) | ES2344737T3 (de) |
HK (1) | HK1081207A1 (de) |
WO (1) | WO2004022585A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4386660B2 (ja) * | 2003-03-25 | 2009-12-16 | 株式会社先端生命科学研究所 | Hbv−rnaを含むhbv粒子 |
ATE493659T1 (de) * | 2004-05-19 | 2011-01-15 | Advanced Life Science Inst Inc | Verfahren zum nachweis von hepatitis-b-virus |
KR20070029199A (ko) * | 2004-05-19 | 2007-03-13 | 멜버른 헬스 | B형 간염에 대한 치료제, 예방제 및 진단제 |
WO2008053900A1 (fr) * | 2006-10-30 | 2008-05-08 | Advanced Life Science Institute, Inc. | Procédé d'analyse immunologique à sensibilité élevée et réactif d'analyse immunologique pour le virus de l'hépatite b |
KR100836745B1 (ko) * | 2007-01-31 | 2008-06-10 | (주)두비엘 | Hbv 백신 및 그의 제조 방법 |
CN103217533B (zh) * | 2012-01-21 | 2016-01-06 | 厦门大学 | Anti-HBc定量检测方法及其在监控慢性乙肝患者病情发展和预测治疗疗效中的用途 |
CA2936092A1 (en) * | 2013-01-23 | 2014-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized hepatitis b core polypeptide |
WO2015133613A1 (ja) * | 2014-03-07 | 2015-09-11 | 雅史 溝上 | B型肝炎ウイルスレポーターベクター、b型肝炎ウイルス様粒子及びそれを用いたb型肝炎治療薬のスクリーニング方法 |
JP7072213B2 (ja) | 2017-12-21 | 2022-05-20 | 国立研究開発法人理化学研究所 | B型肝炎抗原タンパク質を標的としたイメージング用petプローブ |
WO2020255425A1 (ja) * | 2019-06-21 | 2020-12-24 | 国立研究開発法人理化学研究所 | 抗hbv剤 |
CN113322302B (zh) * | 2021-06-02 | 2023-08-11 | 重庆医科大学 | 一种hbv完整病毒颗粒的免疫捕获分子检测方法 |
CN113777329B (zh) * | 2021-09-16 | 2023-07-18 | 何秋富 | 一种视黄醇结合蛋白测定试剂盒及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1234040A2 (de) | 1999-12-03 | 2002-08-28 | Innogenetics N.V. | Hbv sequenzen |
CA2419046C (en) | 2000-08-11 | 2007-10-02 | Advanced Life Science Institute, Inc. | Method for detecting or measuring hbv |
-
2003
- 2003-09-05 DE DE60333370T patent/DE60333370D1/de not_active Expired - Lifetime
- 2003-09-05 ES ES03794268T patent/ES2344737T3/es not_active Expired - Lifetime
- 2003-09-05 CA CA2497972A patent/CA2497972C/en not_active Expired - Lifetime
- 2003-09-05 WO PCT/JP2003/011389 patent/WO2004022585A1/ja active Application Filing
- 2003-09-05 AT AT03794268T patent/ATE473997T1/de not_active IP Right Cessation
- 2003-09-05 EP EP03794268A patent/EP1535927B1/de not_active Expired - Lifetime
- 2003-09-05 KR KR1020057003885A patent/KR101093783B1/ko active IP Right Grant
- 2003-09-05 AU AU2003261977A patent/AU2003261977A1/en not_active Abandoned
- 2003-09-05 CN CNB038246767A patent/CN100547001C/zh not_active Expired - Lifetime
- 2003-09-05 US US10/526,744 patent/US7713532B2/en active Active
- 2003-09-05 JP JP2004534181A patent/JP4459054B2/ja not_active Expired - Lifetime
-
2006
- 2006-01-26 HK HK06101205.3A patent/HK1081207A1/xx not_active IP Right Cessation
-
2009
- 2009-12-16 US US12/654,280 patent/US8383333B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP4459054B2 (ja) | 2010-04-28 |
US8383333B2 (en) | 2013-02-26 |
US20100285444A1 (en) | 2010-11-11 |
JPWO2004022585A1 (ja) | 2005-12-22 |
WO2004022585A1 (ja) | 2004-03-18 |
AU2003261977A1 (en) | 2004-03-29 |
CN1694898A (zh) | 2005-11-09 |
EP1535927A1 (de) | 2005-06-01 |
CA2497972A1 (en) | 2004-03-18 |
CA2497972C (en) | 2016-04-26 |
HK1081207A1 (en) | 2006-05-12 |
CN100547001C (zh) | 2009-10-07 |
ATE473997T1 (de) | 2010-07-15 |
US7713532B2 (en) | 2010-05-11 |
EP1535927A4 (de) | 2006-06-21 |
US20060166187A1 (en) | 2006-07-27 |
KR101093783B1 (ko) | 2011-12-19 |
EP1535927B1 (de) | 2010-07-14 |
KR20050053636A (ko) | 2005-06-08 |
ES2344737T3 (es) | 2010-09-06 |
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