DE60330681D1 - Flüssigkeitshandhabungsinstrument mit einem hohlen kolben - Google Patents
Flüssigkeitshandhabungsinstrument mit einem hohlen kolbenInfo
- Publication number
- DE60330681D1 DE60330681D1 DE60330681T DE60330681T DE60330681D1 DE 60330681 D1 DE60330681 D1 DE 60330681D1 DE 60330681 T DE60330681 T DE 60330681T DE 60330681 T DE60330681 T DE 60330681T DE 60330681 D1 DE60330681 D1 DE 60330681D1
- Authority
- DE
- Germany
- Prior art keywords
- needle
- tool
- plungers
- hollow piston
- liquid handling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/022—Capillary pipettes, i.e. having very small bore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/049—Valves integrated in closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1072—Multiple transfer devices with provision for selective pipetting of individual channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39798902P | 2002-07-23 | 2002-07-23 | |
PCT/US2003/022376 WO2004009238A1 (en) | 2002-07-23 | 2003-07-18 | Liquid handling tool having hollow plunger |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60330681D1 true DE60330681D1 (de) | 2010-02-04 |
Family
ID=30771160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60330681T Expired - Lifetime DE60330681D1 (de) | 2002-07-23 | 2003-07-18 | Flüssigkeitshandhabungsinstrument mit einem hohlen kolben |
Country Status (8)
Country | Link |
---|---|
US (1) | US7438857B2 (de) |
EP (1) | EP1539352B1 (de) |
JP (1) | JP4317816B2 (de) |
AT (1) | ATE452704T1 (de) |
AU (1) | AU2003251996A1 (de) |
DE (1) | DE60330681D1 (de) |
DK (1) | DK1539352T3 (de) |
WO (1) | WO2004009238A1 (de) |
Families Citing this family (70)
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US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US7249529B2 (en) * | 2003-03-28 | 2007-07-31 | Protedyne Corporation | Robotically manipulable sample handling tool |
JP4996248B2 (ja) | 2003-07-31 | 2012-08-08 | ハンディーラブ インコーポレイテッド | 粒子含有サンプルの処理 |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
US7246551B2 (en) * | 2004-07-09 | 2007-07-24 | Protedyne Corporation | Liquid handling device with surface features at a seal |
US7637175B1 (en) | 2004-08-26 | 2009-12-29 | Elemental Scientific, Inc. | Automated sampling device |
US7690275B1 (en) | 2004-08-26 | 2010-04-06 | Elemental Scientific, Inc. | Automated sampling device |
US7201072B1 (en) | 2004-08-26 | 2007-04-10 | Elemental Scientific Inc. | Automated sampling device |
DE102005014572B4 (de) * | 2005-03-31 | 2007-01-04 | Eppendorf Ag | Pipettiervorrichtung |
US7534081B2 (en) | 2005-05-24 | 2009-05-19 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
US7597520B2 (en) | 2005-05-24 | 2009-10-06 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
JP2007232524A (ja) * | 2006-02-28 | 2007-09-13 | Universal Bio Research Co Ltd | タンパク質等溶液ろ過処理方法およびその装置 |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
DK2001990T3 (en) | 2006-03-24 | 2016-10-03 | Handylab Inc | Integrated microfluidic sample processing system and method for its use |
US7998708B2 (en) * | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
DK2021807T3 (da) * | 2006-04-24 | 2013-09-23 | Protedyne Corp | Robotsystem med autonomt betjenelige værktøjer |
US8765076B2 (en) | 2006-11-14 | 2014-07-01 | Handylab, Inc. | Microfluidic valve and method of making same |
WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US7799281B2 (en) | 2007-01-16 | 2010-09-21 | Festo Corporation | Flux concentrator for biomagnetic particle transfer device |
DE102007005323A1 (de) * | 2007-01-29 | 2008-07-31 | Bioplan Consulting Gmbh | Absaugeinrichtung |
EP2006020B1 (de) * | 2007-06-15 | 2011-09-28 | Hamilton Bonaduz AG | Probenbehandlungsanordnung für eine Flüssigkeitsdosiervorrichtung |
JP4959450B2 (ja) * | 2007-07-10 | 2012-06-20 | 株式会社日立ハイテクノロジーズ | 化学分析装置 |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
AU2008276211B2 (en) | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8287820B2 (en) * | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US8016260B2 (en) | 2007-07-19 | 2011-09-13 | Formulatrix, Inc. | Metering assembly and method of dispensing fluid |
EP3756767B1 (de) | 2007-10-02 | 2024-05-01 | Labrador Diagnostics LLC | Modulare poc-vorrichtungen und ihre verwendung |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
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US8100293B2 (en) * | 2009-01-23 | 2012-01-24 | Formulatrix, Inc. | Microfluidic dispensing assembly |
EP2566618B8 (de) * | 2010-05-03 | 2014-07-09 | Integra Biosciences AG | Unbeabsichtigte bewegungs regler für manuell-gesteuerten multi-kanal elektronischen pipetten |
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US9470215B2 (en) | 2010-06-04 | 2016-10-18 | Parker-Hannifin Corporation | Miniaturized syringe pump system and modules |
DE102010041833B4 (de) * | 2010-09-30 | 2014-05-15 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Mikrofluidikchip mit mehreren Zylinder-Kolben-Anordnungen |
TWI690594B (zh) | 2011-01-21 | 2020-04-11 | 美商賽瑞諾斯Ip有限責任公司 | 樣本使用最大化之系統及方法 |
US10259161B2 (en) * | 2011-01-24 | 2019-04-16 | Cornell University | Deposition of materials for edible solid freeform fabrication |
CN106190806B (zh) | 2011-04-15 | 2018-11-06 | 贝克顿·迪金森公司 | 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法 |
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US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
KR102121853B1 (ko) | 2011-09-30 | 2020-06-12 | 벡톤 디킨슨 앤드 컴퍼니 | 일체화된 시약 스트립 |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
CN103998144A (zh) * | 2011-10-28 | 2014-08-20 | 惠普发展公司,有限责任合伙企业 | 并行寻址方法 |
CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
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CN103114035B (zh) * | 2013-03-14 | 2014-04-02 | 东南大学 | 一种全封闭提取、转移和贮存核酸的装置 |
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US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
US5964381A (en) * | 1997-11-12 | 1999-10-12 | Ljl Biosystems, Inc. | Device for projectile dispensing of small volume liquid samples |
JP2001513025A (ja) | 1997-12-23 | 2001-08-28 | ライニン インストルメンツ カンパニー インコーポレイテッド | 補助磁石を備えた手動式ピペット |
US6033911A (en) * | 1998-02-27 | 2000-03-07 | Hamilton Company | Automated assaying device |
US6235002B1 (en) * | 1998-04-17 | 2001-05-22 | Cdc Technologies, Inc. | Syringe for use in fluid-handling apparatus |
AU5407899A (en) | 1998-09-02 | 2000-03-27 | Langerhans Aps | Apparatus for isolation of particles, preferably cell clusters |
DE19845950C1 (de) * | 1998-10-06 | 2000-03-23 | Eppendorf Geraetebau Netheler | Pipettiersystem mit einer Pipettiervorrichtung und mindestens einer daran lösbar befestigten Pipettenspitze |
EP1129346A2 (de) | 1998-10-16 | 2001-09-05 | Intelligent Automation Systems | Automatisierter arbeitsplatz zur kontinuierlichen behandlung |
US6248295B1 (en) * | 1998-11-06 | 2001-06-19 | Rainin Instrument Co., Inc. | Pipette with improved pipette tip and mounting shaft combination |
US6197259B1 (en) * | 1998-11-06 | 2001-03-06 | Rainin Instrument Co., Inc. | Easy eject pipette tip |
US6168761B1 (en) * | 1998-11-06 | 2001-01-02 | Rainin Instrument Co., Inc. | Pipette with improved pipette tip and mounting shaft |
US6258324B1 (en) * | 1999-03-15 | 2001-07-10 | Felix H. Yiu | Pipette dispensing block |
US6244119B1 (en) * | 1999-08-03 | 2001-06-12 | Wallac Oy | Multichannel pipette system and pipette tips therefor |
FR2801108B1 (fr) * | 1999-11-16 | 2002-03-01 | Maxmat S A | Analyseur chimique ou biochimique a regulation de la temperature reactionnelle |
US6365110B1 (en) * | 2000-03-09 | 2002-04-02 | Rainin Instrument | Blowout springless manual air displacement pipette with mechanical assist for aiding in locating and maintaining pipette plunger at a home position |
-
2003
- 2003-07-18 WO PCT/US2003/022376 patent/WO2004009238A1/en active Application Filing
- 2003-07-18 AT AT03765666T patent/ATE452704T1/de not_active IP Right Cessation
- 2003-07-18 DK DK03765666.7T patent/DK1539352T3/da active
- 2003-07-18 AU AU2003251996A patent/AU2003251996A1/en not_active Abandoned
- 2003-07-18 JP JP2004523509A patent/JP4317816B2/ja not_active Expired - Fee Related
- 2003-07-18 DE DE60330681T patent/DE60330681D1/de not_active Expired - Lifetime
- 2003-07-18 US US10/622,414 patent/US7438857B2/en not_active Expired - Fee Related
- 2003-07-18 EP EP03765666A patent/EP1539352B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU2003251996A1 (en) | 2004-02-09 |
US7438857B2 (en) | 2008-10-21 |
EP1539352A1 (de) | 2005-06-15 |
JP4317816B2 (ja) | 2009-08-19 |
EP1539352B1 (de) | 2009-12-23 |
JP2005534015A (ja) | 2005-11-10 |
WO2004009238A1 (en) | 2004-01-29 |
ATE452704T1 (de) | 2010-01-15 |
US20040018119A1 (en) | 2004-01-29 |
DK1539352T3 (da) | 2010-04-19 |
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