DE60322674D1 - Genetischer Marker zur Differenzierung von Mycobakterien - Google Patents
Genetischer Marker zur Differenzierung von MycobakterienInfo
- Publication number
- DE60322674D1 DE60322674D1 DE60322674T DE60322674T DE60322674D1 DE 60322674 D1 DE60322674 D1 DE 60322674D1 DE 60322674 T DE60322674 T DE 60322674T DE 60322674 T DE60322674 T DE 60322674T DE 60322674 D1 DE60322674 D1 DE 60322674D1
- Authority
- DE
- Germany
- Prior art keywords
- mycobacterium
- present
- mycobacteria
- differentiation
- genetic marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000004069 differentiation Effects 0.000 title 1
- 230000002068 genetic effect Effects 0.000 title 1
- 239000003550 marker Substances 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 241001467553 Mycobacterium africanum Species 0.000 abstract 1
- 241000186366 Mycobacterium bovis Species 0.000 abstract 1
- 241001467552 Mycobacterium bovis BCG Species 0.000 abstract 1
- 241001312372 Mycobacterium canettii Species 0.000 abstract 1
- 241000187919 Mycobacterium microti Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02290458A EP1338657B9 (de) | 2002-02-25 | 2002-02-25 | Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine |
| PCT/IB2003/000986 WO2003070981A2 (en) | 2002-02-25 | 2003-02-25 | Seequences specifically deleted mycobacterium tuberculosis genome and their use in diagnostics and as vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60322674D1 true DE60322674D1 (de) | 2008-09-18 |
Family
ID=27635905
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60219589T Expired - Lifetime DE60219589T2 (de) | 2002-02-25 | 2002-02-25 | Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine |
| DE60322674T Expired - Lifetime DE60322674D1 (de) | 2002-02-25 | 2003-02-25 | Genetischer Marker zur Differenzierung von Mycobakterien |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60219589T Expired - Lifetime DE60219589T2 (de) | 2002-02-25 | 2002-02-25 | Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7977047B2 (de) |
| EP (2) | EP1338657B9 (de) |
| JP (1) | JP4738740B2 (de) |
| AT (2) | ATE360097T1 (de) |
| AU (1) | AU2003208539B2 (de) |
| CA (1) | CA2477195C (de) |
| CY (1) | CY1106584T1 (de) |
| DE (2) | DE60219589T2 (de) |
| DK (1) | DK1338657T3 (de) |
| ES (1) | ES2286212T3 (de) |
| PT (1) | PT1338657E (de) |
| WO (1) | WO2003070981A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1350839T3 (da) | 2002-04-05 | 2010-07-12 | Pasteur Institut | Identificering af de virulensassocierede regioner RD1 og RD5, hvilket muliggør udvikling af forbedrede vacciner af M. bovis BCG og M. microti |
| GB0406271D0 (en) | 2004-03-19 | 2004-04-21 | Isis Innovation | Diagnostic test |
| US8044184B2 (en) | 2004-04-26 | 2011-10-25 | Wako Pure Chemical Industries, Ltd. | Probe and primer for tubercle bacillus detection, and method of detecting human tubercle bacillus therewith |
| WO2005118884A1 (en) * | 2004-05-28 | 2005-12-15 | The United States Of America As Represented By The Secretary Of The Navy | A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines |
| WO2007028414A1 (en) * | 2005-09-05 | 2007-03-15 | Bio-Rad Pasteur | Use of both rd9 and is6110 as nucleic acid targets for the diagnosis of tuberculosis, and provision of multiplex-compliant is6110 and rd9 targets |
| BRPI0604958B1 (pt) * | 2006-11-23 | 2022-05-17 | Fundação Oswaldo Cruz | Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg |
| US8367055B2 (en) * | 2009-05-14 | 2013-02-05 | Wisconsin Alumni Research Foundation | Immunogenic compositions against tuberculosis |
| WO2012002598A1 (ko) * | 2010-07-02 | 2012-01-05 | (주)바이오니아 | 결핵 진단용 프라이머, 프로브, 이를 포함하는 키트 및 상기 키트를 이용한 결핵 진단 방법 |
| JP2013055947A (ja) * | 2012-10-26 | 2013-03-28 | Bio-Rad Innovations | 結核の診断のための核酸標的としてのｒｄ９およびｉｓ６１１０の使用、ならびにマルチプレックス−コンプライアントｉｓ６１１０およびｒｄ９標的の提供 |
| EP3578668B1 (de) * | 2014-07-24 | 2020-12-30 | Abbott Molecular Inc. | Verfahren zum nachweis und zur analyse von mycobacterium tuberculosis |
| US10677797B2 (en) | 2016-03-11 | 2020-06-09 | S&R Pharmaceuticals, Llc | Assays and methods for detecting mycobacterial infections |
| CN106868113A (zh) * | 2017-01-24 | 2017-06-20 | 中国疾病预防控制中心传染病预防控制所 | 用于鉴定牛型结核分枝杆菌的snp标记及其应用 |
| WO2022235518A1 (en) * | 2021-05-03 | 2022-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for diagnosing active tuberculosis and progression to active tuberculosis |
| KR20220164261A (ko) | 2021-06-04 | 2022-12-13 | (주)아모레퍼시픽 | 단백질 분해효소 안정성 증진용 조성물, 이를 포함하는 동결건조 조성물, 이를 포함하는 화장품 키트, 및 이의 제조방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| US5714593A (en) * | 1995-02-01 | 1998-02-03 | Institut Pasteur | DNA from mycobacterium tuberculosis which codes for a 45/47 kilodalton protein |
| US6291190B1 (en) * | 1998-08-25 | 2001-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Molecular differences between species of the M. tuberculosis complex |
| FR2791067B1 (fr) * | 1999-03-16 | 2003-01-31 | Pasteur Institut | Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins |
| WO2001002555A1 (en) * | 1999-07-06 | 2001-01-11 | Institut Pasteur | Method of making and identifying attenuated microorganisms, compositions utilizing the sequences responsible for attenuation, and preparations containing attenuated microorganisms |
-
2002
- 2002-02-25 DK DK02290458T patent/DK1338657T3/da active
- 2002-02-25 PT PT02290458T patent/PT1338657E/pt unknown
- 2002-02-25 EP EP02290458A patent/EP1338657B9/de not_active Expired - Lifetime
- 2002-02-25 ES ES02290458T patent/ES2286212T3/es not_active Expired - Lifetime
- 2002-02-25 AT AT02290458T patent/ATE360097T1/de active
- 2002-02-25 DE DE60219589T patent/DE60219589T2/de not_active Expired - Lifetime
-
2003
- 2003-02-25 WO PCT/IB2003/000986 patent/WO2003070981A2/en active IP Right Grant
- 2003-02-25 DE DE60322674T patent/DE60322674D1/de not_active Expired - Lifetime
- 2003-02-25 JP JP2003569872A patent/JP4738740B2/ja not_active Expired - Fee Related
- 2003-02-25 CA CA2477195A patent/CA2477195C/en not_active Expired - Fee Related
- 2003-02-25 US US10/505,405 patent/US7977047B2/en not_active Expired - Fee Related
- 2003-02-25 AU AU2003208539A patent/AU2003208539B2/en not_active Ceased
- 2003-02-25 EP EP03706832A patent/EP1478777B1/de not_active Expired - Lifetime
- 2003-02-25 AT AT03706832T patent/ATE403752T1/de not_active IP Right Cessation
-
2007
- 2007-05-14 CY CY20071100645T patent/CY1106584T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1338657T3 (da) | 2007-07-30 |
| AU2003208539A1 (en) | 2003-09-09 |
| US20060127897A1 (en) | 2006-06-15 |
| WO2003070981A8 (en) | 2004-10-07 |
| EP1478777A2 (de) | 2004-11-24 |
| WO2003070981A2 (en) | 2003-08-28 |
| CY1106584T1 (el) | 2012-01-25 |
| EP1338657B1 (de) | 2007-04-18 |
| EP1338657A1 (de) | 2003-08-27 |
| DE60219589D1 (de) | 2007-05-31 |
| EP1338657B9 (de) | 2007-10-10 |
| ES2286212T3 (es) | 2007-12-01 |
| JP4738740B2 (ja) | 2011-08-03 |
| ATE360097T1 (de) | 2007-05-15 |
| JP2005518203A (ja) | 2005-06-23 |
| CA2477195C (en) | 2015-01-06 |
| AU2003208539B2 (en) | 2008-11-20 |
| DE60219589T2 (de) | 2008-02-14 |
| CA2477195A1 (en) | 2003-08-28 |
| WO2003070981A3 (en) | 2003-12-04 |
| ATE403752T1 (de) | 2008-08-15 |
| US7977047B2 (en) | 2011-07-12 |
| EP1478777B1 (de) | 2008-08-06 |
| PT1338657E (pt) | 2007-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE403752T1 (de) | Genetischer marker zur differenzierung von mycobakterien | |
| ES2157230T3 (es) | Deteccion de mycobacteria por amplificacion multiple de acidos nucleicos. | |
| DE69515029T2 (de) | Nachweis von pathogenen pilzen unter verwendung der polymerase-kettenreaktion | |
| ATE534749T1 (de) | Sonde und primer zum nachweis von tuberkelbazillen sowie verfahren zum nachweis von tuberkelbazillen beim menschen damit | |
| CY1109210T1 (el) | Διαγραφεισες αλληλουχιες στο μ. bovis bcg/m. bovis ΄η μ. tuberculosis, μεθοδος ανιχνευσεως μυκοβακτηριων που χρησιμοποιουν αυτες τις αλληλουχιες και εμβολια | |
| WO2005075673A3 (en) | Detection, identification and differentiation of proteus species using the spacer region | |
| HK1085159A1 (en) | Detection, identification and differentiation of eubacterial taxa using a hybridization assay | |
| Hughes et al. | Molecular analyses of mycobacteria other than the M. tuberculosis complex isolated from Northern Ireland cattle | |
| MY144277A (en) | Methods for detection of mycobacterium tuberculosis | |
| ATE548465T1 (de) | Diagnoseverfahren und dafür geeignete produkte | |
| US20220002785A1 (en) | Rapid identification of bacterial pathogens | |
| WO2007034118A8 (fr) | Procede de detection, dans un echantillon biologique de mycobacteries, et en particulier de mycobacteries caracteristiques de la tuberculose | |
| Chaiprasert et al. | One-tube multiplex PCR method for rapid identification of Mycobacterium tuberculosis | |
| ATE486138T1 (de) | Verfahren zum nachweis von bakterien der gattung mycobacterium (säureresistente bakterien) | |
| ATE446386T1 (de) | Verfahren zur überwachung genomischer dna von organismen | |
| WO2011090875A3 (en) | Primers, sequences and recombinant probes for identification of mycobacterium species | |
| ATE520790T1 (de) | Nachweis, identifizierung und differenzierung von eubakterien unter verwendung eines hybridisierungs-assays | |
| WO2005085478A3 (en) | Detection and identification of mycobacterium and nocardia using primers and probes directed to the seca1 gene | |
| ATE518964T1 (de) | Verfahren und kit zum spezifischen nachweis von m. tuberculosis | |
| Phetsuksiri et al. | Applicability of in-house loop-mediated isothermal amplification for rapid identification of Mycobacterium tuberculosis complex grown on solid media | |
| KR101867934B1 (ko) | 슈도모나스 속 세균의 동정 방법 | |
| FR2857375B1 (fr) | Procede de detection et/ou d'identification de bacteries de genre staphylococcus | |
| Parthiban et al. | Characterization of Pnca Gene Responsible for Pyrazinamidase Enzyme in Mycobacterium tuberculosis Clinical Isolate | |
| Atikovic | Evaluation of a new DNA amplification technique to screen cyanobacteria isolated from drinking water sources for microcystin toxins | |
| ATE476531T1 (de) | Verfahren zur molekularen identifizierung und genotypisierung von bakterien des mykobakteriumtuberkulose-komplexes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |