DE60318723T2 - Methode zur quantitativen bestimmung von polynukleotiden in einem gemisch - Google Patents

Methode zur quantitativen bestimmung von polynukleotiden in einem gemisch Download PDF

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Publication number
DE60318723T2
DE60318723T2 DE60318723T DE60318723T DE60318723T2 DE 60318723 T2 DE60318723 T2 DE 60318723T2 DE 60318723 T DE60318723 T DE 60318723T DE 60318723 T DE60318723 T DE 60318723T DE 60318723 T2 DE60318723 T2 DE 60318723T2
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Prior art keywords
probes
separation
sequences
affinity
tags
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60318723T
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German (de)
English (en)
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DE60318723D1 (de
Inventor
Hans SÖDERLUND
Reetta Satokari
Kari Kataja
Kristiina Takkinen
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VTT Technical Research Centre of Finland Ltd
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VTT Technical Research Centre of Finland Ltd
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Publication of DE60318723T2 publication Critical patent/DE60318723T2/de
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60318723T 2002-07-05 2003-07-04 Methode zur quantitativen bestimmung von polynukleotiden in einem gemisch Expired - Lifetime DE60318723T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20021325 2002-07-05
FI20021325A FI20021325A0 (fi) 2002-07-05 2002-07-05 Menetelmä ja reagenssipakkaus yksittäisten polynukleotidien määrän määrittämiseksi
PCT/FI2003/000544 WO2004005545A1 (en) 2002-07-05 2003-07-04 Method and test kit for quantitative determination of polynucleotides in a mixture

Publications (2)

Publication Number Publication Date
DE60318723D1 DE60318723D1 (de) 2008-03-06
DE60318723T2 true DE60318723T2 (de) 2009-01-15

Family

ID=8564307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60318723T Expired - Lifetime DE60318723T2 (de) 2002-07-05 2003-07-04 Methode zur quantitativen bestimmung von polynukleotiden in einem gemisch

Country Status (12)

Country Link
US (2) US7361461B2 (https=)
EP (2) EP1537238B1 (https=)
JP (1) JP4672365B2 (https=)
AT (1) ATE384141T1 (https=)
AU (1) AU2003242804B2 (https=)
CA (1) CA2489196C (https=)
DE (1) DE60318723T2 (https=)
DK (1) DK1537238T3 (https=)
ES (1) ES2299727T3 (https=)
FI (1) FI20021325A0 (https=)
PT (1) PT1537238E (https=)
WO (1) WO2004005545A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090073A2 (fr) * 2005-02-25 2006-08-31 Comissariat A L'energie Atomique Procede et dispositif pour separer des cibles moleculaires dans un melange complexe
EP1772522A1 (en) * 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Control of preservation by biomarkers
US20070190560A1 (en) * 2006-02-13 2007-08-16 Olga Ornatsky Element-tagged olignucleotide gene expression analysis
EP2677039B8 (en) 2006-05-10 2022-10-05 DxTerity Diagnostics Incorporated Detection of nucleic acid targets using chemically reactive oligonucleotide probes
US20090011944A1 (en) * 2007-02-21 2009-01-08 Valtion Teknillinen Tutkimuskekus Method and test kit for detecting nucleotide variations
FI20075124A0 (fi) * 2007-02-21 2007-02-21 Valtion Teknillinen Menetelmä ja testikitti nukleotidivariaatioiden toteamiseksi
US9976177B2 (en) 2009-04-01 2018-05-22 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (CLPA)
US9745616B2 (en) 2011-05-17 2017-08-29 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
WO2013085631A1 (en) * 2011-10-25 2013-06-13 The Board Of Regents Of The University Of Texas System Methods and compositions for identifying enterovirus
JP6695285B2 (ja) 2014-06-10 2020-05-20 ディクステリティー ダイアグノスティクス インコーポレイテッド 生物学的試料を採取して安定化するためのデバイス及び方法
CN109715827B (zh) 2016-05-06 2023-01-10 明尼苏达大学董事会 分析标准品及其使用方法

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US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
NZ211453A (en) * 1984-03-22 1989-01-06 Biotechnology Research Enterpr Aryl azides, their preparation and use in the detection, localisation and isolation of polynucleotides
US4968602A (en) * 1986-03-05 1990-11-06 Molecular Diagnostics, Inc. Solution-phase single hybridization assay for detecting polynucleotide sequences
AU619170B2 (en) * 1987-01-09 1992-01-23 Abbott Laboratories Diagnostic assays using nucleic acid probes
US5082830A (en) * 1988-02-26 1992-01-21 Enzo Biochem, Inc. End labeled nucleotide probe
US5470705A (en) * 1992-04-03 1995-11-28 Applied Biosystems, Inc. Probe composition containing a binding domain and polymer chain and methods of use
US5633134A (en) * 1992-10-06 1997-05-27 Ig Laboratories, Inc. Method for simultaneously detecting multiple mutations in a DNA sample
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
JP3102800B2 (ja) * 1994-08-19 2000-10-23 パーキン−エルマー コーポレイション 増幅及び連結反応の共役法
WO1996020212A2 (en) 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
US6136531A (en) * 1995-05-08 2000-10-24 Roche Diagnostics Gmbh Method of quantitatively detecting nucleic acids
DE19516196A1 (de) * 1995-05-08 1996-11-14 Boehringer Mannheim Gmbh Verfahren zum quantitativen Nachweis von Nukleinsäuren
US5714386A (en) * 1996-01-11 1998-02-03 Board Of Trustees Of The Leland Stanford Junior University Cy7-allophycocyanin conjugates for use in multiplex fluorescence detection assays
CN1202260C (zh) * 1996-01-23 2005-05-18 佳根基因组学公司 利用大小分离技术分析核酸分子的方法和组合物
EP1736554B1 (en) * 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
CN1251609A (zh) * 1997-02-12 2000-04-26 尤金·Y·查恩 分析聚合物的方法和产品
AU9063398A (en) 1997-09-12 1999-04-05 Exiqon A/S Oligonucleotide analogues
US6562567B2 (en) 1998-01-27 2003-05-13 California Institute Of Technology Method of detecting a nucleic acid
DE69940433D1 (de) * 1998-08-11 2009-04-02 Siemens Healthcare Diagnostics Im nahen infrarot chemilumineszente akridinium derivate und ihre verwendung
US6480791B1 (en) * 1998-10-28 2002-11-12 Michael P. Strathmann Parallel methods for genomic analysis
US6395486B1 (en) * 1999-03-15 2002-05-28 Applera Corporation Probe/mobility modifier complexes for multiplexnucleic acid detection
FI115139B (fi) * 2001-01-10 2005-03-15 Valtion Teknillinen Menetelmä ja testipakkaus solu- tai kudosnäytteissä olevien polynukleotidien määrässä tapahtuvien vaihteluiden kvantitatiiviseen ja/tai vertailevaan arvioimiseen
WO2002097112A2 (en) * 2001-05-26 2002-12-05 Aclara Biosciences, Inc. Catalytic amplification of multiplexed assay signals
WO2003033741A1 (en) * 2001-10-16 2003-04-24 Aclara Biosciences, Inc. Universal e-tag primer and probe compositions and methods
AU2002351193A1 (en) * 2001-11-28 2003-06-10 Mj Bioworks Incorporated Parallel polymorphism scoring by amplification and error correction
ATE414177T1 (de) * 2002-09-30 2008-11-15 Hoffmann La Roche Oligonukleotide zur genotypisierung des thymidylat-synthase gens
US7354706B2 (en) * 2003-09-09 2008-04-08 The Regents Of The University Of Colorado, A Body Corporate Use of photopolymerization for amplification and detection of a molecular recognition event
EP1694869A2 (en) * 2003-11-10 2006-08-30 Investigen, Inc. Methods of preparing nucleic acid for detection

Also Published As

Publication number Publication date
JP4672365B2 (ja) 2011-04-20
CA2489196A1 (en) 2004-01-15
JP2005532058A (ja) 2005-10-27
DK1537238T3 (da) 2008-06-02
US7361461B2 (en) 2008-04-22
CA2489196C (en) 2013-06-11
EP1947200A1 (en) 2008-07-23
EP1537238A1 (en) 2005-06-08
US20080233591A1 (en) 2008-09-25
PT1537238E (pt) 2008-04-22
AU2003242804A1 (en) 2004-01-23
ATE384141T1 (de) 2008-02-15
ES2299727T3 (es) 2008-06-01
WO2004005545A1 (en) 2004-01-15
US20060035228A1 (en) 2006-02-16
EP1537238B1 (en) 2008-01-16
DE60318723D1 (de) 2008-03-06
AU2003242804B2 (en) 2008-06-12
US8143388B2 (en) 2012-03-27
FI20021325A0 (fi) 2002-07-05

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