DE60318559D1 - Verfahren zur herstellung von morpholinderivaten und zwischenprodukte dafür - Google Patents

Verfahren zur herstellung von morpholinderivaten und zwischenprodukte dafür

Info

Publication number
DE60318559D1
DE60318559D1 DE60318559T DE60318559T DE60318559D1 DE 60318559 D1 DE60318559 D1 DE 60318559D1 DE 60318559 T DE60318559 T DE 60318559T DE 60318559 T DE60318559 T DE 60318559T DE 60318559 D1 DE60318559 D1 DE 60318559D1
Authority
DE
Germany
Prior art keywords
morpholine derivatives
intermediates therefor
preparing morpholine
preparing
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60318559T
Other languages
English (en)
Other versions
DE60318559T2 (de
Inventor
Martin Alistair Hayes
Gail Mills
Stephen Swanson
Andrew John Walker
Mark Wilkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE60318559D1 publication Critical patent/DE60318559D1/de
Application granted granted Critical
Publication of DE60318559T2 publication Critical patent/DE60318559T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE60318559T 2002-03-28 2003-03-27 Verfahren zur herstellung von morpholinderivaten und zwischenprodukte dafür Expired - Lifetime DE60318559T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0207450.8A GB0207450D0 (en) 2002-03-28 2002-03-28 Novel compounds
GB0207450 2002-03-28
PCT/EP2003/003343 WO2003082835A1 (en) 2002-03-28 2003-03-27 Process for the preparation of morpholine derivatives and intermediates therefore

Publications (2)

Publication Number Publication Date
DE60318559D1 true DE60318559D1 (de) 2008-02-21
DE60318559T2 DE60318559T2 (de) 2009-01-08

Family

ID=9933999

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60318559T Expired - Lifetime DE60318559T2 (de) 2002-03-28 2003-03-27 Verfahren zur herstellung von morpholinderivaten und zwischenprodukte dafür

Country Status (20)

Country Link
EP (1) EP1487809B1 (de)
JP (1) JP2005532281A (de)
KR (1) KR20050008664A (de)
CN (1) CN1642928A (de)
AR (1) AR039178A1 (de)
AT (1) ATE383349T1 (de)
AU (1) AU2003226760A1 (de)
BR (1) BR0308720A (de)
CA (1) CA2479819A1 (de)
DE (1) DE60318559T2 (de)
ES (1) ES2298539T3 (de)
GB (1) GB0207450D0 (de)
IS (1) IS7401A (de)
MX (1) MXPA04009457A (de)
NO (1) NO20044036L (de)
PL (1) PL373972A1 (de)
RU (1) RU2004125289A (de)
TW (1) TW200401772A (de)
WO (1) WO2003082835A1 (de)
ZA (1) ZA200406548B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1992628A1 (de) 2007-05-18 2008-11-19 Glaxo Group Limited Derivate und Analoge von N-Ethylquinolonen und N-Ethylazaquinolonen
SG11201700566SA (en) 2014-08-22 2017-03-30 Glaxosmithkline Ip Dev Ltd Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection
WO2019168874A1 (en) 2018-02-27 2019-09-06 The Research Foundation For The State University Of New York Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2447732A1 (de) * 1974-10-07 1976-04-08 Wuelfing J A Fa Neue morpholinverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CN1268135A (zh) * 1997-06-23 2000-09-27 吉富制药株式会社 螺杆菌属感染引起的疾病的预防/治疗剂
EP1586567A1 (de) * 2000-09-29 2005-10-19 Glaxo Group Limited Verbindungen verwendbar für die Behandlung von Entzündungskrankheiten

Also Published As

Publication number Publication date
MXPA04009457A (es) 2005-01-25
NO20044036L (no) 2004-09-29
IS7401A (is) 2004-08-12
BR0308720A (pt) 2005-01-04
AU2003226760A1 (en) 2003-10-13
ZA200406548B (en) 2005-09-19
EP1487809A1 (de) 2004-12-22
TW200401772A (en) 2004-02-01
WO2003082835A1 (en) 2003-10-09
CN1642928A (zh) 2005-07-20
KR20050008664A (ko) 2005-01-21
EP1487809B1 (de) 2008-01-09
AR039178A1 (es) 2005-02-09
RU2004125289A (ru) 2005-06-27
ATE383349T1 (de) 2008-01-15
GB0207450D0 (en) 2002-05-08
CA2479819A1 (en) 2003-10-09
PL373972A1 (en) 2005-09-19
DE60318559T2 (de) 2009-01-08
ES2298539T3 (es) 2008-05-16
JP2005532281A (ja) 2005-10-27

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Legal Events

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8364 No opposition during term of opposition