DE60310975T2 - Verwendung von epothilone zur behandlung hyperparathyreoidismus - Google Patents

Verwendung von epothilone zur behandlung hyperparathyreoidismus Download PDF

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Publication number
DE60310975T2
DE60310975T2 DE60310975T DE60310975T DE60310975T2 DE 60310975 T2 DE60310975 T2 DE 60310975T2 DE 60310975 T DE60310975 T DE 60310975T DE 60310975 T DE60310975 T DE 60310975T DE 60310975 T2 DE60310975 T2 DE 60310975T2
Authority
DE
Germany
Prior art keywords
parathyroid
treatment
epothilone
lower alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310975T
Other languages
German (de)
English (en)
Other versions
DE60310975D1 (de
Inventor
A. Eugene Kenner WOLTERING
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Louisiana State University
Original Assignee
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Publication of DE60310975D1 publication Critical patent/DE60310975D1/de
Application granted granted Critical
Publication of DE60310975T2 publication Critical patent/DE60310975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60310975T 2002-10-15 2003-10-13 Verwendung von epothilone zur behandlung hyperparathyreoidismus Expired - Lifetime DE60310975T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41859202P 2002-10-15 2002-10-15
US418592P 2002-10-15
PCT/IB2003/004514 WO2004035050A1 (en) 2002-10-15 2003-10-13 Use of epothilone derivatives for the treatment of hyperparathyroidism

Publications (2)

Publication Number Publication Date
DE60310975D1 DE60310975D1 (de) 2007-02-15
DE60310975T2 true DE60310975T2 (de) 2007-07-12

Family

ID=32107949

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310975T Expired - Lifetime DE60310975T2 (de) 2002-10-15 2003-10-13 Verwendung von epothilone zur behandlung hyperparathyreoidismus

Country Status (15)

Country Link
US (2) US20060142354A1 (enExample)
EP (1) EP1553938B1 (enExample)
JP (1) JP4672368B2 (enExample)
CN (1) CN1297269C (enExample)
AT (1) ATE350034T1 (enExample)
AU (1) AU2003267751A1 (enExample)
BR (1) BR0315293A (enExample)
CA (1) CA2501717C (enExample)
CY (1) CY1106385T1 (enExample)
DE (1) DE60310975T2 (enExample)
DK (1) DK1553938T3 (enExample)
ES (1) ES2279139T3 (enExample)
PT (1) PT1553938E (enExample)
SI (1) SI1553938T1 (enExample)
WO (1) WO2004035050A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
CA2496477C (en) 2002-08-23 2012-10-16 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1155689E (pt) * 1993-07-19 2007-01-31 Angiotech Pharm Inc Composições anti-angiogenicas e metodos de utilização
WO1998022461A1 (de) * 1996-11-18 1998-05-28 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Epothilone c, d, e und f, deren herstellung und deren verwendung als cytostatische mittel bzw. als pflanzenschutzmittel
US6380394B1 (en) * 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
KR20080016756A (ko) * 1998-02-05 2008-02-21 노파르티스 아게 유기화합물 함유 조성물
US6302838B1 (en) * 1998-02-25 2001-10-16 Novartis Ag Cancer treatment with epothilones

Also Published As

Publication number Publication date
HK1080768A1 (en) 2006-05-04
JP2006504751A (ja) 2006-02-09
DE60310975D1 (de) 2007-02-15
CN1703217A (zh) 2005-11-30
ES2279139T3 (es) 2007-08-16
CY1106385T1 (el) 2011-10-12
AU2003267751A1 (en) 2004-05-04
US20110152329A1 (en) 2011-06-23
EP1553938A1 (en) 2005-07-20
CA2501717A1 (en) 2004-04-29
CN1297269C (zh) 2007-01-31
ATE350034T1 (de) 2007-01-15
CA2501717C (en) 2012-09-18
BR0315293A (pt) 2005-08-30
PT1553938E (pt) 2007-03-30
DK1553938T3 (da) 2007-03-26
US20060142354A1 (en) 2006-06-29
SI1553938T1 (sl) 2007-06-30
WO2004035050A1 (en) 2004-04-29
JP4672368B2 (ja) 2011-04-20
EP1553938B1 (en) 2007-01-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN