DE60309206T2 - Neue piperidinderivate als modulatoren vonchemokinrezeptor ccr5 - Google Patents
Neue piperidinderivate als modulatoren vonchemokinrezeptor ccr5 Download PDFInfo
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- DE60309206T2 DE60309206T2 DE60309206T DE60309206T DE60309206T2 DE 60309206 T2 DE60309206 T2 DE 60309206T2 DE 60309206 T DE60309206 T DE 60309206T DE 60309206 T DE60309206 T DE 60309206T DE 60309206 T2 DE60309206 T2 DE 60309206T2
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- Prior art keywords
- alkyl
- phenyl
- compound
- optionally substituted
- formula
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 24
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- 229910052739 hydrogen Inorganic materials 0.000 claims description 9
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- 125000001153 fluoro group Chemical group F* 0.000 claims description 8
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0203820 | 2002-12-20 | ||
| SE0203820A SE0203820D0 (sv) | 2002-12-20 | 2002-12-20 | chemical compounds |
| PCT/SE2003/002005 WO2004056808A1 (en) | 2002-12-20 | 2003-12-18 | Novel piperidine derivatives as modulators of chemokine receptor ccr5 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60309206D1 DE60309206D1 (de) | 2006-11-30 |
| DE60309206T2 true DE60309206T2 (de) | 2007-08-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| DE60309206T Expired - Fee Related DE60309206T2 (de) | 2002-12-20 | 2003-12-18 | Neue piperidinderivate als modulatoren vonchemokinrezeptor ccr5 |
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| EP (1) | EP1572683B1 (enExample) |
| JP (1) | JP2006512364A (enExample) |
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| ES (1) | ES2274295T3 (enExample) |
| SE (1) | SE0203820D0 (enExample) |
| WO (1) | WO2004056808A1 (enExample) |
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| SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| SE0301369D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
| TW200610761A (en) * | 2004-04-23 | 2006-04-01 | Astrazeneca Ab | Chemical compounds |
| SE0401656D0 (sv) * | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | Chemical compounds |
| WO2008129380A1 (en) * | 2007-04-18 | 2008-10-30 | Pfizer Products Inc. | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
| US20110212997A1 (en) * | 2008-09-01 | 2011-09-01 | Neurosearch A/S | Piperidine-4-acetamide derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| AU2009286749A1 (en) * | 2008-09-01 | 2010-03-04 | Neurosearch A/S | Piperidylpropionamide derivatives useful for the treatment of CNS disorders including depression and panic disorder |
| CN102822163B (zh) | 2009-12-23 | 2016-01-20 | 艾恩伍德医药品股份有限公司 | Crth2调节剂 |
| CN102241664B (zh) * | 2010-05-13 | 2014-11-12 | 上海医药工业研究院 | 芳烷二胺类衍生物及其作为抗抑郁症药物的应用 |
| WO2012009137A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| WO2012009134A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
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| IL125658A0 (en) * | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| EP1013276A1 (en) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkanes as CCR5 modulators |
| GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
| GB0013060D0 (en) * | 2000-05-31 | 2000-07-19 | Astrazeneca Ab | Chemical compounds |
| GB0108046D0 (en) * | 2001-03-30 | 2001-05-23 | Astrazeneca Ab | Chemical compounds |
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2002
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2003
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Also Published As
| Publication number | Publication date |
|---|---|
| US20060069120A1 (en) | 2006-03-30 |
| DE60309206D1 (de) | 2006-11-30 |
| WO2004056808A1 (en) | 2004-07-08 |
| JP2006512364A (ja) | 2006-04-13 |
| EP1572683B1 (en) | 2006-10-18 |
| SE0203820D0 (sv) | 2002-12-20 |
| ES2274295T3 (es) | 2007-05-16 |
| ATE342898T1 (de) | 2006-11-15 |
| AU2003288853A1 (en) | 2004-07-14 |
| WO2004056808A8 (en) | 2005-03-17 |
| EP1572683A1 (en) | 2005-09-14 |
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| 8339 | Ceased/non-payment of the annual fee |