JP2006512364A - ケモカイン受容体ｃｃｒ５のモジュレーターとしての新規ピペリジン誘導体 - Google Patents
ケモカイン受容体ｃｃｒ５のモジュレーターとしての新規ピペリジン誘導体 Download PDFInfo
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- JP2006512364A JP2006512364A JP2004562206A JP2004562206A JP2006512364A JP 2006512364 A JP2006512364 A JP 2006512364A JP 2004562206 A JP2004562206 A JP 2004562206A JP 2004562206 A JP2004562206 A JP 2004562206A JP 2006512364 A JP2006512364 A JP 2006512364A
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- alkyl
- phenyl
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- heteroaryl
- substituted
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
Landscapes
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- Bioinformatics & Cheminformatics (AREA)
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- Psychiatry (AREA)
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- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| SE0203820A SE0203820D0 (sv) | 2002-12-20 | 2002-12-20 | chemical compounds |
| PCT/SE2003/002005 WO2004056808A1 (en) | 2002-12-20 | 2003-12-18 | Novel piperidine derivatives as modulators of chemokine receptor ccr5 |
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| SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| SE0301369D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
| TW200610761A (en) * | 2004-04-23 | 2006-04-01 | Astrazeneca Ab | Chemical compounds |
| SE0401656D0 (sv) * | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | Chemical compounds |
| JP4782239B2 (ja) * | 2007-04-18 | 2011-09-28 | ファイザー・プロダクツ・インク | 異常細胞増殖治療のためのスルホニルアミド誘導体 |
| CN102131780A (zh) * | 2008-09-01 | 2011-07-20 | 神经研究公司 | 适用于治疗包括抑郁症和惊恐障碍的中枢神经系统障碍的哌啶基丙酰胺衍生物 |
| JP2012501307A (ja) * | 2008-09-01 | 2012-01-19 | ノイロサーチ アクティーゼルスカブ | ピペリジン−４−アセトアミド誘導体及びモノアミン神経伝達物質再取り込み阻害薬としてのその使用 |
| WO2011079007A1 (en) | 2009-12-23 | 2011-06-30 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| CN102241664B (zh) * | 2010-05-13 | 2014-11-12 | 上海医药工业研究院 | 芳烷二胺类衍生物及其作为抗抑郁症药物的应用 |
| WO2012009134A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| US20130216552A1 (en) | 2010-07-12 | 2013-08-22 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
Citations (1)
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| JPH11147872A (ja) * | 1997-08-18 | 1999-06-02 | F Hoffmann La Roche Ag | Ｃｃｒ−３受容体アンタゴニスト |
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| EP1013276A1 (en) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkanes as CCR5 modulators |
| GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
| GB0013060D0 (en) * | 2000-05-31 | 2000-07-19 | Astrazeneca Ab | Chemical compounds |
| GB0108046D0 (en) * | 2001-03-30 | 2001-05-23 | Astrazeneca Ab | Chemical compounds |
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| JPH11147872A (ja) * | 1997-08-18 | 1999-06-02 | F Hoffmann La Roche Ag | Ｃｃｒ−３受容体アンタゴニスト |
Also Published As
| Publication number | Publication date |
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| AU2003288853A1 (en) | 2004-07-14 |
| EP1572683B1 (en) | 2006-10-18 |
| EP1572683A1 (en) | 2005-09-14 |
| ATE342898T1 (de) | 2006-11-15 |
| SE0203820D0 (sv) | 2002-12-20 |
| WO2004056808A8 (en) | 2005-03-17 |
| US20060069120A1 (en) | 2006-03-30 |
| DE60309206T2 (de) | 2007-08-30 |
| ES2274295T3 (es) | 2007-05-16 |
| WO2004056808A1 (en) | 2004-07-08 |
| DE60309206D1 (de) | 2006-11-30 |
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