DE60230936D1 - Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen - Google Patents

Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen

Info

Publication number
DE60230936D1
DE60230936D1 DE60230936T DE60230936T DE60230936D1 DE 60230936 D1 DE60230936 D1 DE 60230936D1 DE 60230936 T DE60230936 T DE 60230936T DE 60230936 T DE60230936 T DE 60230936T DE 60230936 D1 DE60230936 D1 DE 60230936D1
Authority
DE
Germany
Prior art keywords
estra
benzodioxol
dien
propynyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230936T
Other languages
German (de)
English (en)
Inventor
Cornelis Sennef
Bernardus B W M M Peeters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Application granted granted Critical
Publication of DE60230936D1 publication Critical patent/DE60230936D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60230936T 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen Expired - Lifetime DE60230936D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01204072 2001-10-26

Publications (1)

Publication Number Publication Date
DE60230936D1 true DE60230936D1 (de) 2009-03-05

Family

ID=8181136

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60230936T Expired - Lifetime DE60230936D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen
DE60209248T Expired - Lifetime DE60209248D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60209248T Expired - Lifetime DE60209248D1 (de) 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)-estra-4,9-dien-3-on zur behandlung von schweren depressionen

Country Status (26)

Country Link
US (1) US20040266863A1 (enExample)
EP (2) EP1441739B1 (enExample)
JP (1) JP4647909B2 (enExample)
KR (1) KR20050038580A (enExample)
CN (1) CN100531738C (enExample)
AT (2) ATE420649T1 (enExample)
AU (1) AU2002348996B2 (enExample)
BR (1) BR0213466A (enExample)
CA (1) CA2463446C (enExample)
CY (1) CY1110173T1 (enExample)
DE (2) DE60230936D1 (enExample)
DK (1) DK1652526T3 (enExample)
EC (1) ECSP045080A (enExample)
ES (1) ES2319563T3 (enExample)
HR (1) HRP20040370B1 (enExample)
HU (1) HUP0500070A3 (enExample)
IL (2) IL161248A0 (enExample)
IS (1) IS2702B (enExample)
MX (1) MXPA04003781A (enExample)
NO (1) NO332978B1 (enExample)
NZ (1) NZ532429A (enExample)
PL (1) PL206687B1 (enExample)
PT (1) PT1652526E (enExample)
RU (1) RU2302245C2 (enExample)
WO (1) WO2003037354A1 (enExample)
ZA (1) ZA200403088B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080061A1 (en) * 2003-07-23 2005-04-14 Corcept Therapeutics, Inc. Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
AU2011236053B2 (en) * 2004-11-19 2014-06-26 Merck Sharpe & Dohme B.V. Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CN101060860B (zh) * 2004-11-19 2013-07-17 Msd欧斯股份有限公司 用于治疗抑郁症的包含选择性5-羟色胺再摄取抑制剂和糖皮质激素受体拮抗剂的药物组合
JP2009535430A (ja) * 2006-05-02 2009-10-01 コーセプト セラピューティクス， インコーポレイテッド Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用
JP5804395B2 (ja) * 2011-02-03 2015-11-04 ポップ テスト オンコロジー エルエルシー 診断と治療のためのシステムおよび方法
WO2012145258A1 (en) * 2011-04-18 2012-10-26 Pop Test Cortisol Llc Hair loss treatment
US8986677B2 (en) * 2012-07-30 2015-03-24 Pop Test Cortisol Llc Therapeutic compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814333A (en) * 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients
DE4447401A1 (de) * 1994-12-23 1996-07-04 Schering Ag 14,17-C¶2¶-überbrückte Steroide
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) * 1997-06-30 1999-01-28 Forschungszentrum Juelich Gmbh Magnetflußsensor mit ringförmiger Sonde
DK1023074T3 (da) * 1997-10-06 2006-11-06 Univ Leland Stanford Junior Fremgangsmåder til behandling af psykose forbundet med glucocorticoid-relateret dysfunktion
CN1820756A (zh) * 2001-03-23 2006-08-23 科塞普特治疗公司 使用糖皮质激素受体特效拮抗剂治疗压力症的方法
EP1390037B1 (en) * 2001-05-04 2010-12-22 Corcept Therapeutics, Inc. Use of glucocorticoid receptor-specific antagonists for the treatment of delirium
NZ531477A (en) * 2001-08-31 2006-10-27 Corcept Therapeutics Inc Use of a glucocorticoid receptor antagonist comprising a steroidal skeleton with at least one phenyl-containing moiety in the 11-beta position of the steroidal skeleton to decrease cognitive deterioration in adults with Down's syndrome

Also Published As

Publication number Publication date
EP1652526A2 (en) 2006-05-03
MXPA04003781A (es) 2004-07-30
KR20050038580A (ko) 2005-04-27
IL161248A (en) 2010-12-30
NO20041651L (no) 2004-04-23
RU2302245C2 (ru) 2007-07-10
JP2005521637A (ja) 2005-07-21
HUP0500070A2 (hu) 2005-04-28
ATE317700T1 (de) 2006-03-15
EP1441739B1 (en) 2006-02-15
PL369261A1 (en) 2005-04-18
AU2002348996B2 (en) 2008-06-05
HK1087357A1 (en) 2006-10-13
CN100531738C (zh) 2009-08-26
RU2004116082A (ru) 2005-05-10
NZ532429A (en) 2004-10-29
CA2463446A1 (en) 2003-05-08
JP4647909B2 (ja) 2011-03-09
ZA200403088B (en) 2005-01-24
EP1652526A3 (en) 2006-08-02
CY1110173T1 (el) 2015-01-14
HRP20040370A2 (en) 2004-08-31
PT1652526E (pt) 2009-02-06
HRP20040370B1 (hr) 2012-09-30
ATE420649T1 (de) 2009-01-15
DK1652526T3 (da) 2009-05-18
DE60209248D1 (de) 2006-04-20
ECSP045080A (es) 2004-06-28
EP1441739A1 (en) 2004-08-04
PL206687B1 (pl) 2010-09-30
BR0213466A (pt) 2004-11-09
CN1582153A (zh) 2005-02-16
WO2003037354A1 (en) 2003-05-08
HUP0500070A3 (en) 2012-09-28
CA2463446C (en) 2010-02-23
IS7204A (is) 2004-03-31
NO332978B1 (no) 2013-02-11
ES2319563T3 (es) 2009-05-08
IS2702B (is) 2010-11-15
US20040266863A1 (en) 2004-12-30
EP1652526B1 (en) 2009-01-14
IL161248A0 (en) 2004-09-27

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