DE60228960D1 - Kompakte automatisierte vorrichtung zur trennung von radionukliden - Google Patents

Kompakte automatisierte vorrichtung zur trennung von radionukliden

Info

Publication number
DE60228960D1
DE60228960D1 DE60228960T DE60228960T DE60228960D1 DE 60228960 D1 DE60228960 D1 DE 60228960D1 DE 60228960 T DE60228960 T DE 60228960T DE 60228960 T DE60228960 T DE 60228960T DE 60228960 D1 DE60228960 D1 DE 60228960D1
Authority
DE
Germany
Prior art keywords
radionuclides
automated device
separation
separating radionuclides
compact automated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60228960T
Other languages
English (en)
Inventor
John E Young
John J Hines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PG Research Foundation Inc
Original Assignee
PG Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PG Research Foundation Inc filed Critical PG Research Foundation Inc
Application granted granted Critical
Publication of DE60228960D1 publication Critical patent/DE60228960D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • G01N30/08Preparation using an enricher
    • G01N2030/085Preparation using an enricher using absorbing precolumn
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8804Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/468Flow patterns using more than one column involving switching between different column configurations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8651Recording, data aquisition, archiving and storage
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005Isotope delivery systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S422/00Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
    • Y10S422/903Radioactive material apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Circuits Of Receivers In General (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Toys (AREA)
DE60228960T 2001-06-22 2002-06-21 Kompakte automatisierte vorrichtung zur trennung von radionukliden Expired - Lifetime DE60228960D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30013401P 2001-06-22 2001-06-22
PCT/US2002/019609 WO2003000375A1 (en) 2001-06-22 2002-06-21 Compact automated radionuclide separator

Publications (1)

Publication Number Publication Date
DE60228960D1 true DE60228960D1 (de) 2008-10-30

Family

ID=23157852

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60228960T Expired - Lifetime DE60228960D1 (de) 2001-06-22 2002-06-21 Kompakte automatisierte vorrichtung zur trennung von radionukliden

Country Status (11)

Country Link
US (1) US6770195B2 (de)
EP (1) EP1404429B1 (de)
JP (1) JP4309254B2 (de)
CN (1) CN1306981C (de)
AT (1) ATE408818T1 (de)
AU (1) AU2002320124B2 (de)
CA (1) CA2451154C (de)
DE (1) DE60228960D1 (de)
EA (1) EA005712B1 (de)
WO (1) WO2003000375A1 (de)
ZA (1) ZA200309765B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6998052B2 (en) * 2002-04-12 2006-02-14 Pg Research Foundation Multicolumn selectivity inversion generator for production of ultrapure radionuclides
US7087206B2 (en) * 2002-04-12 2006-08-08 Pg Research Foundation Multicolumn selectivity inversion generator for production of high purity actinium for use in therapeutic nuclear medicine
EP1772157A1 (de) * 2005-10-06 2007-04-11 Karl-Heinz Jansen Modul-Bausatz und Syntheseverfahren zum Herstellen von Radiopharmaka und Radionukliden
US7402251B2 (en) * 2005-12-28 2008-07-22 Mann Welding Company Chromatography column and method of operation
KR100742639B1 (ko) * 2006-01-19 2007-07-25 한국원자력안전기술원 방사성핵종 분리용 다수 시료 동시자동분리장치 및 그를이용한 우라늄 (u) 자동분리방법
US7554098B2 (en) * 2007-04-20 2009-06-30 Battelle Memorial Institute Medical isotope generator systems
EP2197421A1 (de) * 2007-08-31 2010-06-23 Amgen, Inc Protein-formulierung in festem zustand
FR2990956B1 (fr) * 2012-05-24 2014-07-04 Areva Med Sas Procede et appareil pour la production de plomb 212 a usage medical
US9299466B2 (en) * 2013-10-30 2016-03-29 NorthStar Medical Radioisotopes LLC System for processing and tracking radionuclides
CN104268374B (zh) * 2014-09-09 2017-07-28 中国核电工程有限公司 计算长寿命放射性核素的短半衰期子核岸边沉积外照射剂量的方法
US20160223205A1 (en) * 2015-01-30 2016-08-04 Oscar Yonghwan CHOI Timer device for stove
CN106732481B (zh) * 2017-01-10 2019-04-05 苏州大学 一种高锝酸根吸附剂及其合成方法与在处理放射性废水中的应用
US11798700B2 (en) 2018-03-26 2023-10-24 The University Of British Columbia Systems, apparatus and methods for separating actinium, radium, and thorium
CN109521457B (zh) * 2018-09-25 2022-10-21 中国辐射防护研究院 一种基于信息准则的γ辐射源项划分方法及系统
CN116594053B (zh) * 2023-07-18 2024-01-19 清华大学 放射性溶液中超铀α核素、90Sr和137Cs的组分离系统及装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59145022A (ja) * 1983-02-08 1984-08-20 Japan Atom Energy Res Inst リチウム同位体を分離する方法
US4762617A (en) * 1987-01-15 1988-08-09 The United States Of America As Represented By The United States Department Of Energy Size-exclusion chromatography system for macromolecular interaction analysis
US5110474A (en) * 1990-04-09 1992-05-05 Arch Development Corporation Method for liquid chromatographic extraction of strontium from acid solutions
US5368736A (en) * 1993-07-26 1994-11-29 The United States Of America As Represented By The United States Department Of Energy Process for the separation and purification of yttrium-90 for medical applications
CA2146177C (en) * 1995-04-03 2000-09-05 Adrian P. Wade Intelligent flow analysis network
US5774782A (en) * 1996-05-22 1998-06-30 Lockheed Martin Energy Systems, Inc. Technetium-99m generator system
US6126909A (en) * 1996-08-26 2000-10-03 Arch Development Corporation Process and apparatus for the production of BI-212 and a use thereof
US5729821A (en) * 1996-12-10 1998-03-17 Lockheed Martin Energy Research Coirporation Concentration of perrhenate and pertechnetate solutions
JP2001504235A (ja) * 1997-03-14 2001-03-27 トランスジエノミツク・インコーポレーテツド ポリヌクレオチド分離のバンド列の表示
US5854968A (en) * 1997-06-09 1998-12-29 Arch Development Corporation Process and apparatus for the production of BI-213 cations
EP1073609A4 (de) * 1998-03-30 2002-08-28 Sloan Kettering Inst Cancer Bismuth-213-generator und seine anwendung
US6153154A (en) * 1998-05-27 2000-11-28 Battelle Memorial Institute Method for sequential injection of liquid samples for radioisotope separations
PT967618E (pt) * 1998-06-22 2003-12-31 Europ Economic Community Metodo e dispositivo para a preparacao de bi-213 para utilizacao terapeutica humana
US6245305B1 (en) * 1998-11-10 2001-06-12 Battelle Memorial Institute Method of separating and purifying gadolinium-153
US6157036A (en) * 1998-12-02 2000-12-05 Cedars-Sinai Medical Center System and method for automatically eluting and concentrating a radioisotope
EP1331976A2 (de) * 1999-12-22 2003-08-06 TRANSGENOMIC, Inc. System und verfahren zur automatisch angepassten polynukleotid-ionen-chromatographie
ATE527038T1 (de) * 2001-06-22 2011-10-15 Pg Res Foundation Inc Automatisiertes system und verfahren zur trennung von radionukliden

Also Published As

Publication number Publication date
EP1404429B1 (de) 2008-09-17
EA005712B1 (ru) 2005-04-28
EP1404429A4 (de) 2005-02-02
CN1518475A (zh) 2004-08-04
EP1404429A1 (de) 2004-04-07
CA2451154A1 (en) 2003-01-03
CN1306981C (zh) 2007-03-28
EA200301245A1 (ru) 2004-06-24
ZA200309765B (en) 2004-09-28
AU2002320124B2 (en) 2006-12-14
JP2005500517A (ja) 2005-01-06
WO2003000375A1 (en) 2003-01-03
US6770195B2 (en) 2004-08-03
ATE408818T1 (de) 2008-10-15
US20020195391A1 (en) 2002-12-26
JP4309254B2 (ja) 2009-08-05
CA2451154C (en) 2012-02-07

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