DE60226322D1 - Locus der maus-lambda-leichtkette - Google Patents

Locus der maus-lambda-leichtkette

Info

Publication number
DE60226322D1
DE60226322D1 DE60226322T DE60226322T DE60226322D1 DE 60226322 D1 DE60226322 D1 DE 60226322D1 DE 60226322 T DE60226322 T DE 60226322T DE 60226322 T DE60226322 T DE 60226322T DE 60226322 D1 DE60226322 D1 DE 60226322D1
Authority
DE
Germany
Prior art keywords
light chain
lambda light
locus
mouse lambda
deleted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60226322T
Other languages
English (en)
Other versions
DE60226322T3 (de
DE60226322T2 (de
Inventor
Marianne Brueggemann
Xiangang Zou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crescendo Biologics Ltd
Original Assignee
Babraham Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9917128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60226322(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Babraham Institute filed Critical Babraham Institute
Publication of DE60226322D1 publication Critical patent/DE60226322D1/de
Application granted granted Critical
Publication of DE60226322T2 publication Critical patent/DE60226322T2/de
Publication of DE60226322T3 publication Critical patent/DE60226322T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/054—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
    • A01K2217/058—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function due to expression of inhibitory nucleic acid, e.g. siRNA, antisense
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Position Input By Displaying (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Details Of Television Scanning (AREA)
  • User Interface Of Digital Computer (AREA)
DE60226322.0T 2001-06-21 2002-06-21 Locus der maus-lambda-leichtkette Expired - Lifetime DE60226322T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0115256 2001-06-21
GBGB0115256.0A GB0115256D0 (en) 2001-06-21 2001-06-21 Mouse light chain locus
EP02732970.5A EP1399559B2 (de) 2001-06-21 2002-06-21 Locus der maus-lambda-leichtkette
PCT/GB2002/002867 WO2003000737A2 (en) 2001-06-21 2002-06-21 MOUSE μ LIGHT CHAIN LOCUS

Publications (3)

Publication Number Publication Date
DE60226322D1 true DE60226322D1 (de) 2008-06-12
DE60226322T2 DE60226322T2 (de) 2009-07-09
DE60226322T3 DE60226322T3 (de) 2016-03-03

Family

ID=9917128

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60226322.0T Expired - Lifetime DE60226322T3 (de) 2001-06-21 2002-06-21 Locus der maus-lambda-leichtkette

Country Status (11)

Country Link
US (4) US7541513B2 (de)
EP (2) EP1956092A1 (de)
AT (1) ATE393826T1 (de)
AU (1) AU2002304460A1 (de)
CY (1) CY1108227T1 (de)
DE (1) DE60226322T3 (de)
DK (1) DK1399559T4 (de)
ES (1) ES2305245T5 (de)
GB (2) GB0115256D0 (de)
PT (1) PT1399559E (de)
WO (1) WO2003000737A2 (de)

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Also Published As

Publication number Publication date
US9439405B2 (en) 2016-09-13
US20170049083A1 (en) 2017-02-23
EP1399559B1 (de) 2008-04-30
WO2003000737A2 (en) 2003-01-03
EP1399559A2 (de) 2004-03-24
US10194645B2 (en) 2019-02-05
GB2392672A (en) 2004-03-10
US8367888B2 (en) 2013-02-05
ATE393826T1 (de) 2008-05-15
DK1399559T3 (da) 2008-08-25
EP1956092A1 (de) 2008-08-13
GB2392672B (en) 2005-05-11
ES2305245T3 (es) 2008-11-01
ES2305245T5 (es) 2015-12-11
DE60226322T3 (de) 2016-03-03
US20130046079A1 (en) 2013-02-21
AU2002304460A1 (en) 2003-01-08
EP1399559B2 (de) 2015-09-02
US20110093961A1 (en) 2011-04-21
CY1108227T1 (el) 2014-02-12
PT1399559E (pt) 2008-07-29
WO2003000737A3 (en) 2003-09-25
US20050060763A1 (en) 2005-03-17
DK1399559T4 (en) 2015-12-14
US7541513B2 (en) 2009-06-02
GB0115256D0 (en) 2001-08-15
GB0400676D0 (en) 2004-02-18
DE60226322T2 (de) 2009-07-09

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