DE60220779T2 - Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten - Google Patents
Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten Download PDFInfo
- Publication number
- DE60220779T2 DE60220779T2 DE60220779T DE60220779T DE60220779T2 DE 60220779 T2 DE60220779 T2 DE 60220779T2 DE 60220779 T DE60220779 T DE 60220779T DE 60220779 T DE60220779 T DE 60220779T DE 60220779 T2 DE60220779 T2 DE 60220779T2
- Authority
- DE
- Germany
- Prior art keywords
- formula
- ethyl
- compound
- tetrahydropyrid
- trifluoromethylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 239000012453 solvate Substances 0.000 claims abstract description 17
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- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 12
- 239000001257 hydrogen Substances 0.000 claims abstract description 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 11
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 125000005843 halogen group Chemical group 0.000 claims abstract description 7
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- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
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- Biomedical Technology (AREA)
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- Communicable Diseases (AREA)
- Neurosurgery (AREA)
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- Pain & Pain Management (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0105360A FR2823748B1 (fr) | 2001-04-20 | 2001-04-20 | Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| FR0105360 | 2001-04-20 | ||
| FR0105362 | 2001-04-20 | ||
| FR0105362A FR2823750B1 (fr) | 2001-04-20 | 2001-04-20 | Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenant |
| PCT/FR2002/001343 WO2002085888A1 (fr) | 2001-04-20 | 2002-04-19 | Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60220779D1 DE60220779D1 (de) | 2007-08-02 |
| DE60220779T2 true DE60220779T2 (de) | 2008-03-06 |
Family
ID=26212980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60220779T Expired - Lifetime DE60220779T2 (de) | 2001-04-20 | 2002-04-19 | Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7186720B2 (https=) |
| EP (1) | EP1383762B1 (https=) |
| JP (1) | JP4324382B2 (https=) |
| AT (1) | ATE365162T1 (https=) |
| DE (1) | DE60220779T2 (https=) |
| WO (1) | WO2002085888A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2831166B1 (fr) * | 2001-10-18 | 2004-02-27 | Sanofi Synthelabo | Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant |
| US7759337B2 (en) | 2005-03-03 | 2010-07-20 | Amgen Inc. | Phthalazine compounds and methods of use |
| FR2883285B1 (fr) * | 2005-03-17 | 2007-05-18 | Sanofi Aventis Sa | Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl) -1,2,3,6-tetrahudro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique |
| US7662824B2 (en) * | 2005-03-18 | 2010-02-16 | Janssen Pharmaceutica Nv | Acylhydrazones as kinase modulators |
| HRP20170103T1 (hr) | 2005-12-21 | 2017-03-24 | Janssen Pharmaceutica N.V. | Triazolopiridazini kao modulatori tirozin kinaze |
| US8772481B2 (en) | 2008-10-10 | 2014-07-08 | Amgen Inc. | Aza- and diaza-phthalazine compounds as P38 map kinase modulators and methods of use thereof |
| US8497269B2 (en) | 2008-10-10 | 2013-07-30 | Amgen Inc. | Phthalazine compounds as p38 map kinase modulators and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3421641A1 (de) * | 1984-06-09 | 1985-12-12 | Merck Patent Gmbh, 6100 Darmstadt | Indolderivate |
| FR2736053B1 (fr) * | 1995-06-28 | 1997-09-19 | Sanofi Sa | Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
| FR2762514B1 (fr) | 1997-04-29 | 1999-10-22 | Sanofi Sa | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation |
-
2002
- 2002-04-19 US US10/475,460 patent/US7186720B2/en not_active Expired - Fee Related
- 2002-04-19 WO PCT/FR2002/001343 patent/WO2002085888A1/fr not_active Ceased
- 2002-04-19 JP JP2002583415A patent/JP4324382B2/ja not_active Expired - Fee Related
- 2002-04-19 DE DE60220779T patent/DE60220779T2/de not_active Expired - Lifetime
- 2002-04-19 AT AT02727676T patent/ATE365162T1/de not_active IP Right Cessation
- 2002-04-19 EP EP02727676A patent/EP1383762B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002085888A1 (fr) | 2002-10-31 |
| JP4324382B2 (ja) | 2009-09-02 |
| US20040138264A1 (en) | 2004-07-15 |
| ATE365162T1 (de) | 2007-07-15 |
| EP1383762B1 (fr) | 2007-06-20 |
| US7186720B2 (en) | 2007-03-06 |
| EP1383762A1 (fr) | 2004-01-28 |
| JP2004525983A (ja) | 2004-08-26 |
| DE60220779D1 (de) | 2007-08-02 |
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