DE60213874D1 - Verfahren zur herstellung von protease hemmenden zwischenprodukten - Google Patents

Verfahren zur herstellung von protease hemmenden zwischenprodukten

Info

Publication number
DE60213874D1
DE60213874D1 DE60213874T DE60213874T DE60213874D1 DE 60213874 D1 DE60213874 D1 DE 60213874D1 DE 60213874 T DE60213874 T DE 60213874T DE 60213874 T DE60213874 T DE 60213874T DE 60213874 D1 DE60213874 D1 DE 60213874D1
Authority
DE
Germany
Prior art keywords
intermediate products
inhibiting intermediate
preparing protease
present
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60213874T
Other languages
English (en)
Other versions
DE60213874T2 (de
Inventor
Daniel Doan
D Davis
Claiborne Lovelace
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of DE60213874D1 publication Critical patent/DE60213874D1/de
Application granted granted Critical
Publication of DE60213874T2 publication Critical patent/DE60213874T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60213874T 2001-09-20 2002-09-16 Verfahren zur herstellung von protease hemmenden zwischenprodukten Expired - Fee Related DE60213874T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32369201P 2001-09-20 2001-09-20
US323692P 2001-09-20
PCT/US2002/029315 WO2003024974A2 (en) 2001-09-20 2002-09-16 Process for preparing protease inhibitor intermediates

Publications (2)

Publication Number Publication Date
DE60213874D1 true DE60213874D1 (de) 2006-09-21
DE60213874T2 DE60213874T2 (de) 2007-10-18

Family

ID=23260324

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60213874T Expired - Fee Related DE60213874T2 (de) 2001-09-20 2002-09-16 Verfahren zur herstellung von protease hemmenden zwischenprodukten

Country Status (8)

Country Link
US (1) US7145024B2 (de)
EP (1) EP1465897B1 (de)
JP (1) JP2005510467A (de)
AT (1) ATE335745T1 (de)
AU (1) AU2002326925A1 (de)
DE (1) DE60213874T2 (de)
ES (1) ES2265052T3 (de)
WO (1) WO2003024974A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050261507A1 (en) * 2002-06-27 2005-11-24 Doan Brian D Preparation of stereoisomers of (3alpha/beta, 6alpha/beta)hexahydrofuro[2,3-b]furan-3-ol
WO2004060895A1 (ja) * 2002-12-27 2004-07-22 Sumitomo Chemical Company, Limited ヘキサヒドロフロフラノール誘導体の製造方法、その中間体及びその製造方法
EP1638960A4 (de) * 2003-06-27 2009-04-01 Smithkline Beecham Corp Herstellung chemischer verbindungen
SI2089371T1 (sl) 2006-11-09 2011-05-31 Tibotec Pharm Ltd Postopki za pripravo heksahidrofuro(2,3-b)furan-3-ola
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
ES2516916T3 (es) 2010-01-28 2014-10-31 Mapi Pharma Limited Procedimiento para la preparación de darunavir e intermedios de darunavir
WO2011156095A2 (en) 2010-06-10 2011-12-15 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
DK2643326T3 (en) 2010-11-23 2017-01-09 Mylan Laboratories Ltd A process for the preparation of (3R, 3aS, 6aR) -hexahydrofuro [2,3-b] furan-3-ol
JP2014533523A (ja) 2011-09-02 2014-12-15 ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア バイオセンシングおよび薬剤供給のためのマイクロ針アレイ
CN106977526A (zh) * 2017-05-25 2017-07-25 河南省商业科学研究所有限责任公司 一种3,4‑二甲基噻吩[2,3‑b]并噻吩的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026749A1 (en) * 1993-05-14 1994-11-24 Merck & Co., Inc. Hiv protease inhibitors
US5810766A (en) 1995-02-28 1998-09-22 Chiron Vision Corporation Infusion/aspiration apparatus with removable cassette

Also Published As

Publication number Publication date
WO2003024974A3 (en) 2004-07-29
EP1465897A2 (de) 2004-10-13
AU2002326925A1 (en) 2003-04-01
US7145024B2 (en) 2006-12-05
ATE335745T1 (de) 2006-09-15
WO2003024974A2 (en) 2003-03-27
EP1465897B1 (de) 2006-08-09
US20040204595A1 (en) 2004-10-14
JP2005510467A (ja) 2005-04-21
ES2265052T3 (es) 2007-02-01
DE60213874T2 (de) 2007-10-18

Similar Documents

Publication Publication Date Title
DE50312217D1 (de) Verfahren zur herstellung von 1-olefinen durch katalytische spaltung von 1-alkoxyalkanen
ATE296094T1 (de) Stickstoffmonoxid bildende zusammensetzungen zur behandlung von nagelbettinfektionen
ATE288479T1 (de) Verfahren fuer die replikation von influenza in zellkultur und die bei diesem verfahren hergestellten influenza-viren
WO2004096818A3 (en) Method and compositions for identifying anti-hiv therapeutic compounds
DE60110106D1 (de) Verfahren zur herstellung von pankreasenzym enthaltende mikrosphären mit hoher stabilität
TW200726479A (en) Method of inducing neutralizing antibodies to human immunodeficiency virus
WO2004075850A3 (en) Polyvalent immunogen
ATE354648T1 (de) Verfahren zur herstellung eines virus inaktivierten thrombin präparates
DE60213874D1 (de) Verfahren zur herstellung von protease hemmenden zwischenprodukten
ATE449104T1 (de) Verfahren zur reinigung von fibrinogen
ATE430160T1 (de) Lipopeptid-stereoisomere, verfahren zu ihrer herstellung und nützliche zwischenprodukte
ATE472251T1 (de) Verfahren zur fruchtausdünnung
TW200517121A (en) Immunogen
ATE321850T1 (de) Verfahren zur herstellung von polynucleotivarianten
ATE204851T1 (de) Verfahren zur herstellung von retrovial protease hemmenden zwischenprodukten
DE60124289D1 (de) Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op)
ATE404577T1 (de) Verfahren zur herstellung von eplerenon
DE60219927D1 (de) Verfahren zur herstellung von glycopeptid- phosphonat-derivaten
ATE425187T1 (de) Materialien und methoden zur behandlung von hepatitis c
WO2003100036A3 (fr) Sulfolipides antiretroviraux extraits de spirulines, leur procede d'obtention, les compositions les contenant et leur utilisation comme inhibiteurs de la transcriptase inverse des virus vih.
WO2001060838A3 (en) Aids ancestral viruses and vaccines
WO2005016952A3 (en) Polyvalent immunogen
DE602004031129D1 (de) Verfahren zur herstellung von quetiapin
ATE299851T1 (de) Verfahren zur herstellung von zwischenprodukten
ATE297385T1 (de) Verfahren zur reinigung von 2-chlor-5- chlormethylthiazol

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee