ATE321850T1 - Verfahren zur herstellung von polynucleotivarianten - Google Patents
Verfahren zur herstellung von polynucleotivariantenInfo
- Publication number
- ATE321850T1 ATE321850T1 AT02760263T AT02760263T ATE321850T1 AT E321850 T1 ATE321850 T1 AT E321850T1 AT 02760263 T AT02760263 T AT 02760263T AT 02760263 T AT02760263 T AT 02760263T AT E321850 T1 ATE321850 T1 AT E321850T1
- Authority
- AT
- Austria
- Prior art keywords
- polynucleotivariants
- producing
- polynucleotides
- preparation
- discloses
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 108091008146 restriction endonucleases Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202822 | 2001-07-23 | ||
| EP01203458 | 2001-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321850T1 true ATE321850T1 (de) | 2006-04-15 |
Family
ID=26076966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02760263T ATE321850T1 (de) | 2001-07-23 | 2002-07-23 | Verfahren zur herstellung von polynucleotivarianten |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20050130140A1 (de) |
| EP (1) | EP1409666B1 (de) |
| AT (1) | ATE321850T1 (de) |
| DE (1) | DE60210298T2 (de) |
| WO (1) | WO2003010311A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010047183A1 (en) | 2000-04-05 | 2001-11-29 | Salvatore Privitera | Surgical device for the collection of soft tissue |
| US20080146965A1 (en) | 2003-08-11 | 2008-06-19 | Salvatore Privitera | Surgical Device for The Collection of Soft Tissue |
| US7402383B2 (en) * | 2001-07-23 | 2008-07-22 | Dsm Ip Assets B.V. | Process for preparing variant polynucleotides |
| KR100803093B1 (ko) * | 2005-10-07 | 2008-02-18 | 한국해양연구원 | 광학선택적 에폭사이드 가수분해효소 및 이를 이용한광학순도 에폭사이드의 제조방법 |
| US8053191B2 (en) | 2006-08-31 | 2011-11-08 | Westend Asset Clearinghouse Company, Llc | Iterative nucleic acid assembly using activation of vector-encoded traits |
| WO2011056872A2 (en) | 2009-11-03 | 2011-05-12 | Gen9, Inc. | Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly |
| WO2011066185A1 (en) | 2009-11-25 | 2011-06-03 | Gen9, Inc. | Microfluidic devices and methods for gene synthesis |
| US9217144B2 (en) | 2010-01-07 | 2015-12-22 | Gen9, Inc. | Assembly of high fidelity polynucleotides |
| EP2637780B1 (de) | 2010-11-12 | 2022-02-09 | Gen9, Inc. | Proteinanordnungen und verfahren zu ihrer herstellung und verwendung |
| WO2012078312A2 (en) | 2010-11-12 | 2012-06-14 | Gen9, Inc. | Methods and devices for nucleic acids synthesis |
| IL302248A (en) * | 2011-08-26 | 2023-06-01 | Gen9 Inc | Compositions and methods for high fidelity assembly of nucleic acids |
| EA201400836A8 (ru) | 2012-01-23 | 2016-03-31 | ДСМ АйПи АССЕТС Б.В. | Получение дитерпена |
| US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
| AU2013251701A1 (en) | 2012-04-24 | 2014-10-30 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
| EP2864531B2 (de) | 2012-06-25 | 2022-08-03 | Gen9, Inc. | Verfahren zur nukleinsäurezusammenfügung und -sequenzierung mit hohem durchsatz |
| MX367033B (es) | 2013-05-31 | 2019-08-02 | Dsm Ip Assets Bv | Microorganismos para la produccion de diterpeno. |
| CA2914900A1 (en) | 2013-07-15 | 2015-01-22 | Dsm Ip Assets B.V. | Recombinant microorganism and process for the production of steviol glycosides |
| DK3027632T3 (da) | 2013-07-31 | 2019-06-17 | Dsm Ip Assets Bv | Indvinding af steviolglycosider fra et fermenteringsmedium |
| CA3198626A1 (en) | 2020-10-22 | 2022-04-28 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| CN121127603A (zh) | 2023-04-20 | 2025-12-12 | 帝斯曼知识产权资产管理有限公司 | 用于产生罗汉果苷的菌株和方法 |
| WO2025144785A2 (en) | 2023-12-28 | 2025-07-03 | Dsm Ip Assets B.V. | Cells and methods for the production of glycosylated compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335160B1 (en) * | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| GB9712512D0 (en) * | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| IL136574A0 (en) * | 1997-12-08 | 2001-06-14 | California Inst Of Techn | A method for forming a polynucleotide of desired properties |
| US6951719B1 (en) * | 1999-08-11 | 2005-10-04 | Proteus S.A. | Process for obtaining recombined nucleotide sequences in vitro, libraries of sequences and sequences thus obtained |
| FR2782323B1 (fr) * | 1998-08-12 | 2002-01-11 | Proteus | Procede de production in vitro de sequences polynucleotidiques recombinees, banques de sequences et sequences ainsi obtenues |
| US20030092023A1 (en) * | 1998-08-12 | 2003-05-15 | Daniel Dupret | Method of shuffling polynucleotides using templates |
| WO2002068692A1 (en) * | 2001-02-21 | 2002-09-06 | Maxygen, Inc. | Methods for improving or altering promoter/enhancer properties |
| US20030087254A1 (en) * | 2001-04-05 | 2003-05-08 | Simon Delagrave | Methods for the preparation of polynucleotide libraries and identification of library members having desired characteristics |
-
2002
- 2002-07-23 AT AT02760263T patent/ATE321850T1/de not_active IP Right Cessation
- 2002-07-23 DE DE60210298T patent/DE60210298T2/de not_active Expired - Lifetime
- 2002-07-23 US US10/484,680 patent/US20050130140A1/en not_active Abandoned
- 2002-07-23 WO PCT/EP2002/008222 patent/WO2003010311A2/en not_active Ceased
- 2002-07-23 EP EP02760263A patent/EP1409666B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1409666B1 (de) | 2006-03-29 |
| EP1409666A2 (de) | 2004-04-21 |
| US20050130140A1 (en) | 2005-06-16 |
| DE60210298T2 (de) | 2006-11-02 |
| WO2003010311A3 (en) | 2003-12-11 |
| DE60210298D1 (de) | 2006-05-18 |
| WO2003010311A2 (en) | 2003-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |