DE60212044D1 - Test der bukkalen Auflösung pharmazeutisch aktiver Stoffe - Google Patents

Test der bukkalen Auflösung pharmazeutisch aktiver Stoffe

Info

Publication number
DE60212044D1
DE60212044D1 DE60212044T DE60212044T DE60212044D1 DE 60212044 D1 DE60212044 D1 DE 60212044D1 DE 60212044 T DE60212044 T DE 60212044T DE 60212044 T DE60212044 T DE 60212044T DE 60212044 D1 DE60212044 D1 DE 60212044D1
Authority
DE
Germany
Prior art keywords
test
active substances
pharmaceutically active
buccal dissolution
buccal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60212044T
Other languages
English (en)
Other versions
DE60212044T2 (de
Inventor
Lyn Hughes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohm and Haas Co
Original Assignee
Rohm and Haas Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohm and Haas Co filed Critical Rohm and Haas Co
Application granted granted Critical
Publication of DE60212044D1 publication Critical patent/DE60212044D1/de
Publication of DE60212044T2 publication Critical patent/DE60212044T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60212044T 2001-11-05 2002-10-23 Test der bukkalen Auflösung für pharmazeutisch aktive Substrate Expired - Lifetime DE60212044T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7140 2001-11-05
US10/007,140 US7470545B2 (en) 2001-11-05 2001-11-05 Buccal dissolution of active substances

Publications (2)

Publication Number Publication Date
DE60212044D1 true DE60212044D1 (de) 2006-07-20
DE60212044T2 DE60212044T2 (de) 2007-01-04

Family

ID=21724452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60212044T Expired - Lifetime DE60212044T2 (de) 2001-11-05 2002-10-23 Test der bukkalen Auflösung für pharmazeutisch aktive Substrate

Country Status (6)

Country Link
US (1) US7470545B2 (de)
EP (1) EP1308724B1 (de)
JP (1) JP3713259B2 (de)
KR (1) KR100954393B1 (de)
DE (1) DE60212044T2 (de)
TW (1) TWI312068B (de)

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US7470545B2 (en) * 2001-11-05 2008-12-30 Rohm And Haas Company Buccal dissolution of active substances
US7024955B2 (en) * 2003-03-01 2006-04-11 Symyx Technologies, Inc. Methods and systems for dissolution testing
GB2406641B (en) * 2003-08-19 2007-09-12 Wicken Technology Ltd Materials analysis
CN101087594B (zh) * 2004-11-05 2011-08-03 史密丝克莱恩比彻姆公司 药物分析装置及方法
US7331251B2 (en) * 2005-06-22 2008-02-19 Idaho State University Dissolution testing of solid dosage forms intended to be administered in the oral cavity
TW200732644A (en) * 2005-10-25 2007-09-01 Rohm & Haas Dissolution test equipment and methods for testing having improved filtration system
US20090155920A1 (en) * 2007-11-12 2009-06-18 Symyx Technologies, Inc. High throughput dissolution and precipitation apparatus and method
WO2011123040A1 (en) * 2010-03-31 2011-10-06 Ge Healthcare Bio-Sciences Ab A parallel separation system
JP5586098B2 (ja) 2010-08-04 2014-09-10 ローム アンド ハース カンパニー 改良された溶出試験装置
CA2972211C (en) 2011-04-29 2019-02-05 Moberg Pharma Ab Pharmaceutical compositions comprising a local anaesthetic such as bupivacaine for local administration to the mouth or throat
US10322949B2 (en) 2012-03-15 2019-06-18 Flodesign Sonics, Inc. Transducer and reflector configurations for an acoustophoretic device
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10737953B2 (en) 2012-04-20 2020-08-11 Flodesign Sonics, Inc. Acoustophoretic method for use in bioreactors
CN103018414A (zh) * 2012-10-25 2013-04-03 中南大学 一种药物制剂活性成分个性化体外溶出检测方法和溶出装置
EP2988842A4 (de) * 2013-04-25 2017-01-25 Flodesign Sonics Inc. Trägerstoffentfernung von pharmakologischen proben
US9745569B2 (en) 2013-09-13 2017-08-29 Flodesign Sonics, Inc. System for generating high concentration factors for low cell density suspensions
EP3092049A1 (de) 2014-01-08 2016-11-16 Flodesign Sonics Inc. Akustophoresevorrichtung mit doppelter akustophoresekammer
US9744483B2 (en) 2014-07-02 2017-08-29 Flodesign Sonics, Inc. Large scale acoustic separation device
JP6386193B2 (ja) 2014-11-21 2018-09-05 アブソープション システムズ グループ リミテッド ライアビリティ カンパニー 薬物の溶解、吸収及び透過の付随評価のためのシステム、並びに該システムを使用する方法
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
CN105043814B (zh) * 2015-07-01 2017-11-28 阿拉山口出入境检验检疫局综合技术服务中心 一种液化石油气取样样品混合装置
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
CN105223326B (zh) * 2015-09-23 2017-01-18 天津中医药大学 一种中药口服速释制剂中活性成分的体外分类方法
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
JP2020513248A (ja) 2016-10-19 2020-05-14 フロデザイン ソニックス， インク．Ｆｌｏｄｅｓｉｇｎ Ｓｏｎｉｃｓ， Ｉｎｃ． 音響による親和性細胞抽出
WO2019082169A1 (en) * 2017-10-28 2019-05-02 Hamid Gourabi DISSOLUTION TEST FOR SENSITIVE MEDICINES
KR20220066413A (ko) 2017-12-14 2022-05-24 프로디자인 소닉스, 인크. 음향 트랜스듀서 구동기 및 제어기
KR102169337B1 (ko) 2018-08-22 2020-10-23 주식회사 도원엔바이로 질소와 인의 흡착형 세라믹 미생물 담체 및 이의 제조방법
CN109030398B (zh) * 2018-08-28 2024-05-17 中国烟草总公司郑州烟草研究院 一种口含烟烟碱释放行为检测方法及其专用测试仪器
US11668723B2 (en) 2019-07-09 2023-06-06 Logan Instruments Corporation Automated dissolution/permeation testing system
CN113311126B (zh) * 2021-07-30 2021-11-02 湖南慧泽生物医药科技有限公司 模拟药物体内溶出的溶出仪系统及检测药物溶出的方法

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US3620675A (en) * 1969-02-10 1971-11-16 Upjohn Co Apparatus for the measurement of dissolution rates
US3801280A (en) * 1971-11-11 1974-04-02 Upjohn Co Solubility-dissolution test apparatus and method
US4279860A (en) * 1980-06-25 1981-07-21 Smolen Victor F Multiple injector flow through dissolution cell for dissolution testing apparatus
US4578244A (en) * 1982-04-23 1986-03-25 Pharmacontrol Corp. Sampling apparatus for obtaining a plurality of fluid samples
US4594902A (en) * 1985-08-23 1986-06-17 Pennwalt Corporation Method and apparatus for sample retrieval from pharmaceutical dissolution testers
CH680472A5 (de) * 1989-12-18 1992-08-31 Sotax Ag
FR2655874B1 (fr) * 1989-12-20 1992-03-13 Prolabo Sa Cellule de dissolution pour solides et appareil d'etude de la cinetique de dissolution la comportant.
CA2257106C (en) * 1996-06-04 2002-04-23 Euro-Celtique, S.A. Improvements in detection systems and methods for predicting the dissolution curve of a drug from a pharmaceutical dosage form
US6174497B1 (en) 1997-06-04 2001-01-16 Euro-Celtique, S.A. Detection systems and methods for predicting the dissolution curve of a drug from a pharmaceutical dosage form
US6004822A (en) * 1997-04-04 1999-12-21 Alfred LaGreca Device and method for measuring solubility and for performing titration studies of submilliliter quantities
JP2000283977A (ja) 1999-03-31 2000-10-13 Shimadzu Corp 錠剤溶出試験機
US7470545B2 (en) * 2001-11-05 2008-12-30 Rohm And Haas Company Buccal dissolution of active substances
US6799123B2 (en) * 2001-11-05 2004-09-28 Lyn Hughes Dissolution test equipment and method

Also Published As

Publication number Publication date
EP1308724A3 (de) 2004-06-23
US20030087457A1 (en) 2003-05-08
EP1308724B1 (de) 2006-06-07
DE60212044T2 (de) 2007-01-04
JP3713259B2 (ja) 2005-11-09
US7470545B2 (en) 2008-12-30
JP2004003937A (ja) 2004-01-08
KR100954393B1 (ko) 2010-04-26
KR20030038416A (ko) 2003-05-16
TWI312068B (en) 2009-07-11
EP1308724A2 (de) 2003-05-07

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Legal Events

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