DE60204791T2 - Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen - Google Patents

Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen Download PDF

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Publication number
DE60204791T2
DE60204791T2 DE60204791T DE60204791T DE60204791T2 DE 60204791 T2 DE60204791 T2 DE 60204791T2 DE 60204791 T DE60204791 T DE 60204791T DE 60204791 T DE60204791 T DE 60204791T DE 60204791 T2 DE60204791 T2 DE 60204791T2
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DE
Germany
Prior art keywords
formula
compound
solvent
acid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60204791T
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German (de)
English (en)
Other versions
DE60204791D1 (de
Inventor
Wenxue Wu
Hongbiao Liao
J. David TSAI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
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Application filed by Schering Corp filed Critical Schering Corp
Publication of DE60204791D1 publication Critical patent/DE60204791D1/de
Application granted granted Critical
Publication of DE60204791T2 publication Critical patent/DE60204791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60204791T 2001-10-15 2002-10-15 Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen Expired - Lifetime DE60204791T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32956101P 2001-10-15 2001-10-15
US329561P 2001-10-15
PCT/US2002/033118 WO2003033488A1 (en) 2001-10-15 2002-10-15 Synthesis of 4-(piperidyl) (2-pyridyl)methanone-(e)-o-methyloxime and its salts

Publications (2)

Publication Number Publication Date
DE60204791D1 DE60204791D1 (de) 2005-07-28
DE60204791T2 true DE60204791T2 (de) 2006-05-18

Family

ID=23285979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60204791T Expired - Lifetime DE60204791T2 (de) 2001-10-15 2002-10-15 Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen

Country Status (13)

Country Link
EP (1) EP1436282B1 (enExample)
JP (1) JP4425632B2 (enExample)
CN (2) CN100360520C (enExample)
AR (1) AR036881A1 (enExample)
AT (1) ATE298333T1 (enExample)
CA (1) CA2463510A1 (enExample)
DE (1) DE60204791T2 (enExample)
DK (1) DK1436282T3 (enExample)
ES (1) ES2240839T3 (enExample)
MX (1) MXPA04003477A (enExample)
PT (1) PT1436282E (enExample)
WO (1) WO2003033488A1 (enExample)
ZA (1) ZA200402070B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007075702A2 (en) * 2005-12-21 2007-07-05 Schering Corporation Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and h3 receptor antagonist/inverse agonist
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
JP7021643B2 (ja) * 2017-02-08 2022-02-17 日産化学株式会社 オキシイミノ化合物の幾何異性体の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020507A1 (es) * 2000-10-17 2002-06-25 Schering Corp Compuestos no-imidazoles como antagonistas del receptor histamina h3

Also Published As

Publication number Publication date
MXPA04003477A (es) 2004-07-30
ZA200402070B (en) 2005-04-29
ES2240839T3 (es) 2005-10-16
AR036881A1 (es) 2004-10-13
JP2005506357A (ja) 2005-03-03
EP1436282B1 (en) 2005-06-22
DE60204791D1 (de) 2005-07-28
PT1436282E (pt) 2005-10-31
ATE298333T1 (de) 2005-07-15
CN101157685A (zh) 2008-04-09
HK1062683A1 (en) 2004-11-19
WO2003033488A1 (en) 2003-04-24
JP4425632B2 (ja) 2010-03-03
DK1436282T3 (da) 2005-07-11
CA2463510A1 (en) 2003-04-24
CN1678605A (zh) 2005-10-05
CN100360520C (zh) 2008-01-09
EP1436282A1 (en) 2004-07-14

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