MXPA04003477A - Sintesis de 4-(piperidil)-(2-piridil)metanona-(e)-o-metiloxima y sales. - Google Patents

Sintesis de 4-(piperidil)-(2-piridil)metanona-(e)-o-metiloxima y sales.

Info

Publication number
MXPA04003477A
MXPA04003477A MXPA04003477A MXPA04003477A MXPA04003477A MX PA04003477 A MXPA04003477 A MX PA04003477A MX PA04003477 A MXPA04003477 A MX PA04003477A MX PA04003477 A MXPA04003477 A MX PA04003477A MX PA04003477 A MXPA04003477 A MX PA04003477A
Authority
MX
Mexico
Prior art keywords
methanone
piperidyl
pyridyl
synthesis
methyloxime
Prior art date
Application number
MXPA04003477A
Other languages
English (en)
Inventor
David J S Tsai
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MXPA04003477A publication Critical patent/MXPA04003477A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

En una modalidad, la presente invencion describe la sintesis de 4-(piperidil)-(2-piridil)metanona-(E)-o-metiloxima, diclorhidrato, monoclorhidrato y base libre, y compuestos similares, con alta pureza estereoquimica.
MXPA04003477A 2001-10-15 2002-10-15 Sintesis de 4-(piperidil)-(2-piridil)metanona-(e)-o-metiloxima y sales. MXPA04003477A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32956101P 2001-10-15 2001-10-15
PCT/US2002/033118 WO2003033488A1 (en) 2001-10-15 2002-10-15 Synthesis of 4-(piperidyl) (2-pyridyl)methanone-(e)-o-methyloxime and its salts

Publications (1)

Publication Number Publication Date
MXPA04003477A true MXPA04003477A (es) 2004-07-30

Family

ID=23285979

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003477A MXPA04003477A (es) 2001-10-15 2002-10-15 Sintesis de 4-(piperidil)-(2-piridil)metanona-(e)-o-metiloxima y sales.

Country Status (14)

Country Link
EP (1) EP1436282B1 (es)
JP (1) JP4425632B2 (es)
CN (2) CN100360520C (es)
AR (1) AR036881A1 (es)
AT (1) ATE298333T1 (es)
CA (1) CA2463510A1 (es)
DE (1) DE60204791T2 (es)
DK (1) DK1436282T3 (es)
ES (1) ES2240839T3 (es)
HK (1) HK1062683A1 (es)
MX (1) MXPA04003477A (es)
PT (1) PT1436282E (es)
WO (1) WO2003033488A1 (es)
ZA (1) ZA200402070B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009521452A (ja) * 2005-12-21 2009-06-04 シェーリング コーポレイション コレステロール降下剤およびｈ３受容体アンタゴニスト／逆アゴニストを使用する非アルコール性脂肪性肝疾患の処置
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
US10710977B2 (en) * 2017-02-08 2020-07-14 Nissan Chemical Corporation Method for producing geometrical isomer of oximino compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020507A1 (es) * 2000-10-17 2002-06-25 Schering Corp Compuestos no-imidazoles como antagonistas del receptor histamina h3

Also Published As

Publication number Publication date
DE60204791T2 (de) 2006-05-18
ES2240839T3 (es) 2005-10-16
ZA200402070B (en) 2005-04-29
JP4425632B2 (ja) 2010-03-03
CN1678605A (zh) 2005-10-05
AR036881A1 (es) 2004-10-13
WO2003033488A1 (en) 2003-04-24
HK1062683A1 (en) 2004-11-19
PT1436282E (pt) 2005-10-31
DK1436282T3 (da) 2005-07-11
EP1436282A1 (en) 2004-07-14
CN100360520C (zh) 2008-01-09
ATE298333T1 (de) 2005-07-15
EP1436282B1 (en) 2005-06-22
CN101157685A (zh) 2008-04-09
DE60204791D1 (de) 2005-07-28
JP2005506357A (ja) 2005-03-03
CA2463510A1 (en) 2003-04-24

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