DE602007008357D1 - Antikörperabhängiger zellulärer zytotoxizitätstest - Google Patents

Antikörperabhängiger zellulärer zytotoxizitätstest

Info

Publication number
DE602007008357D1
DE602007008357D1 DE602007008357T DE602007008357T DE602007008357D1 DE 602007008357 D1 DE602007008357 D1 DE 602007008357D1 DE 602007008357 T DE602007008357 T DE 602007008357T DE 602007008357 T DE602007008357 T DE 602007008357T DE 602007008357 D1 DE602007008357 D1 DE 602007008357D1
Authority
DE
Germany
Prior art keywords
antibody
dependent cellular
cellular cytotoxicity
methods
assay medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007008357T
Other languages
English (en)
Inventor
John Kunich
Cheng Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE602007008357D1 publication Critical patent/DE602007008357D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602007008357T 2006-01-04 2007-01-04 Antikörperabhängiger zellulärer zytotoxizitätstest Active DE602007008357D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75630106P 2006-01-04 2006-01-04
PCT/US2007/060108 WO2007082138A2 (en) 2006-01-04 2007-01-04 Antibody-dependent cellular cytotoxicity assay

Publications (1)

Publication Number Publication Date
DE602007008357D1 true DE602007008357D1 (de) 2010-09-23

Family

ID=38222750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007008357T Active DE602007008357D1 (de) 2006-01-04 2007-01-04 Antikörperabhängiger zellulärer zytotoxizitätstest

Country Status (18)

Country Link
US (1) US20090155821A1 (de)
EP (2) EP2246700A1 (de)
JP (1) JP2009522583A (de)
KR (1) KR20080085080A (de)
CN (1) CN101395471A (de)
AT (1) ATE477486T1 (de)
AU (1) AU2007204777B2 (de)
BR (1) BRPI0706420A2 (de)
CA (1) CA2636183A1 (de)
DE (1) DE602007008357D1 (de)
ES (1) ES2349885T3 (de)
HK (1) HK1116253A1 (de)
IL (1) IL192546A (de)
MX (1) MX2008008700A (de)
PL (1) PL1977241T3 (de)
PT (1) PT1977241E (de)
RU (1) RU2409816C2 (de)
WO (1) WO2007082138A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
CA2550274A1 (en) 2003-11-12 2005-05-26 Acea Biosciences, Inc. Real time electronic cell sensing systems and applications for cell-based assays
JP2009244197A (ja) * 2008-03-31 2009-10-22 Hioki Ee Corp 薬剤感受性試験方法及び装置
WO2009137440A1 (en) 2008-05-05 2009-11-12 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
CA2787157A1 (en) * 2010-02-11 2011-08-18 F. Hoffmann-La Roche Ag 3d adcc nk facs assay
EA024436B1 (ru) * 2012-10-29 2016-09-30 Общество С Ограниченной Ответственностью "Диатек" Способ ранней диагностики онкологических заболеваний
KR20150124980A (ko) * 2013-02-28 2015-11-06 텔레메디슨 업 클로즈 인코포레이티드 샘플의 균수를 평가하는 진단 장치
CN103278539B (zh) * 2013-06-07 2015-06-17 浙江大学 检测海洋水产品腹泻性毒素的细胞阻抗传感器装置及方法
CN103675031B (zh) * 2013-12-18 2015-09-02 江苏大学 一种高通量细胞毒性检测方法
WO2017087945A1 (en) * 2015-11-20 2017-05-26 Acea Biosciences, Inc. Cell-substrate impedance monitoring of cancer cells
GB201619909D0 (en) * 2016-11-24 2017-01-11 Cell Therapy Catapult Ltd Impedance assay
US11746328B2 (en) 2017-03-03 2023-09-05 Agilent Technologies, Inc. Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
US20210364494A1 (en) * 2017-08-01 2021-11-25 Acea Biosciences, Inc. Cell-substrate impedance monitoring of cancer cells of different lineage, origin, or stage
CN110320352A (zh) * 2019-07-25 2019-10-11 上海轩锋生物科技有限公司 基于抗体依赖的细胞介导细胞毒性的抗体效价检测方法
USD941488S1 (en) 2020-02-07 2022-01-18 Agilent Technologies, Inc. Instrument for analyzing biological cells
CA3239939A1 (en) * 2021-12-06 2023-06-15 Xiaoqing JIA 3d bioassays to measure antibody-dependent cell-mediated cytotoxicity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840313A (en) * 1990-09-27 1998-11-24 Syntello Vaccine Development Kb Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
CA2238003C (en) * 1995-12-01 2005-02-22 Innogenetics N.V. Impedimetric detection system and method of production thereof
GB9812783D0 (en) * 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
DK2270149T3 (en) * 1999-04-09 2016-05-09 Kyowa Hakko Kirin Co Ltd PROCEDURE TO CONTROL THE ACTIVITY OF IMMUNOLOGICAL FUNCTIONAL MOLECULE.
US7470533B2 (en) 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
ATE448482T1 (de) 2002-07-20 2009-11-15 Acea Biosciences Inc Vorrichtungen auf impedanzbasis sowie verfahren zur verwendung in assays
US7468255B2 (en) * 2002-12-20 2008-12-23 Acea Biosciences Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
JP5026072B2 (ja) * 2003-07-01 2012-09-12 イミューノメディクス、インコーポレイテッド 二重特異性抗体の多価キャリヤー
CA2550274A1 (en) * 2003-11-12 2005-05-26 Acea Biosciences, Inc. Real time electronic cell sensing systems and applications for cell-based assays
CA2556219A1 (en) 2004-02-09 2005-08-25 Acea Biosciences, Inc. Methods for assaying cells using cell-substrate impedance monitoring
EP1773980B1 (de) * 2004-08-04 2015-07-01 Acea Biosciences, Inc. Verfahren zur untersuchung auf natürliche killerzellen, cytotoxisches t-lymphozyt- und neutrophilvermitteltes töten von targetzellen unter verwendung von mikroelektronischer zellenabtasttechnologie in echtzeit
WO2006110466A2 (en) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. CANCER-RELATED GENES (PTPϵ)

Also Published As

Publication number Publication date
RU2008131931A (ru) 2010-02-10
CN101395471A (zh) 2009-03-25
JP2009522583A (ja) 2009-06-11
AU2007204777A1 (en) 2007-07-19
EP2246700A1 (de) 2010-11-03
US20090155821A1 (en) 2009-06-18
KR20080085080A (ko) 2008-09-22
EP1977241B1 (de) 2010-08-11
WO2007082138A3 (en) 2007-09-13
BRPI0706420A2 (pt) 2011-03-29
PT1977241E (pt) 2010-09-16
PL1977241T3 (pl) 2011-02-28
EP1977241A2 (de) 2008-10-08
CA2636183A1 (en) 2007-07-19
WO2007082138A2 (en) 2007-07-19
HK1116253A1 (en) 2008-12-19
MX2008008700A (es) 2009-05-21
IL192546A (en) 2012-02-29
RU2409816C2 (ru) 2011-01-20
ATE477486T1 (de) 2010-08-15
AU2007204777B2 (en) 2011-12-01
ES2349885T3 (es) 2011-01-12
IL192546A0 (en) 2009-08-03

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Legal Events

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8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN