DE602006020589D1 - Verwendung von azabicyclohexan-derivaten - Google Patents

Verwendung von azabicyclohexan-derivaten

Info

Publication number
DE602006020589D1
DE602006020589D1 DE602006020589T DE602006020589T DE602006020589D1 DE 602006020589 D1 DE602006020589 D1 DE 602006020589D1 DE 602006020589 T DE602006020589 T DE 602006020589T DE 602006020589 T DE602006020589 T DE 602006020589T DE 602006020589 D1 DE602006020589 D1 DE 602006020589D1
Authority
DE
Germany
Prior art keywords
disorder
azabicyclohexan
derivatives
nervosa
hyperchondriasis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020589T
Other languages
English (en)
Inventor
Dieter Hamprecht
Christian Heidbreder
Sergio Melotto
Fabrizio Micheli
Tadataka Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE602006020589D1 publication Critical patent/DE602006020589D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal Substances (AREA)
DE602006020589T 2005-08-22 2006-08-21 Verwendung von azabicyclohexan-derivaten Active DE602006020589D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0517193.9A GB0517193D0 (en) 2005-08-22 2005-08-22 Novel use
PCT/EP2006/008314 WO2007022980A1 (en) 2005-08-22 2006-08-21 Use of azabicyclo hexane derivatives

Publications (1)

Publication Number Publication Date
DE602006020589D1 true DE602006020589D1 (de) 2011-04-21

Family

ID=35098098

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020589T Active DE602006020589D1 (de) 2005-08-22 2006-08-21 Verwendung von azabicyclohexan-derivaten

Country Status (20)

Country Link
US (2) US20090036461A1 (de)
EP (1) EP1917013B1 (de)
JP (1) JP5166267B2 (de)
KR (1) KR101363090B1 (de)
CN (1) CN101291669B (de)
AT (1) ATE500826T1 (de)
AU (1) AU2006284077B2 (de)
BR (1) BRPI0614929A2 (de)
CA (1) CA2620090A1 (de)
CR (1) CR9807A (de)
DE (1) DE602006020589D1 (de)
EA (1) EA016084B1 (de)
ES (1) ES2361933T3 (de)
GB (1) GB0517193D0 (de)
IL (1) IL189435A0 (de)
MA (1) MA29774B1 (de)
MX (1) MX2008002564A (de)
NO (1) NO20081314L (de)
WO (1) WO2007022980A1 (de)
ZA (1) ZA200801352B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2060570E (pt) * 2004-02-23 2012-05-07 Glaxo Group Ltd Derivados de azabiciclo(3.1.0)-hexano úteis como moduladores dos receptores d3 da dopamina
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
ATE484502T1 (de) * 2005-06-14 2010-10-15 Glaxo Group Ltd Neue verbindungen
KR20170005888A (ko) 2005-07-27 2017-01-16 뉴로반스, 인크. 신규 1-아릴-3-아자바이사이클로［3.1.0］헥산：제조 방법 및 신경 정신 질환 치료를 위한 용도
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
EP1919908B1 (de) * 2005-08-22 2010-11-10 Glaxo Group Limited Triazolderivate als modulatoren von dopamin-d3-rezeptoren
GB0607899D0 (en) 2006-04-03 2006-05-31 Glaxo Group Ltd Process for preparing heterocyclic derivatives
US8163927B2 (en) * 2006-04-03 2012-04-24 Glaxo Group Limited Azabicyclo [3.1.0] hexane derivatives as modulators of dopamine D3 receptors
WO2007113260A1 (en) * 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
CN102803224A (zh) * 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
WO2012033956A1 (en) * 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating
US9314600B2 (en) 2012-04-15 2016-04-19 Bioconnect Systems, Inc. Delivery system for implantable flow connector
WO2019146740A1 (ja) 2018-01-26 2019-08-01 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する環式化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
US20020103198A1 (en) * 2000-12-04 2002-08-01 Fliri Anton F.J Acylamino cyclopropane derivatives
PT2060570E (pt) * 2004-02-23 2012-05-07 Glaxo Group Ltd Derivados de azabiciclo(3.1.0)-hexano úteis como moduladores dos receptores d3 da dopamina
SE526837C2 (sv) * 2004-02-24 2005-11-08 Kongsberg Automotive Asa Växelspakstransmission
BRPI0518823A2 (pt) * 2004-12-02 2008-12-09 Abbott Gmbh & Co Kg compostos de triazol adequados para o tratamento de transtornos que respondam À modulaÇço do receptor d3 da dopamina
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
ATE484502T1 (de) * 2005-06-14 2010-10-15 Glaxo Group Ltd Neue verbindungen
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
EP1919908B1 (de) * 2005-08-22 2010-11-10 Glaxo Group Limited Triazolderivate als modulatoren von dopamin-d3-rezeptoren
GB0517191D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
BRPI0709660A2 (pt) * 2006-04-03 2011-07-19 Glaxo Group Limided derivados de azabiciclo [3,1,0] hexila como moduladores dos receptores de dopamina d3
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
AU2006284077B2 (en) 2012-05-17
WO2007022980A1 (en) 2007-03-01
EP1917013B1 (de) 2011-03-09
CN101291669B (zh) 2012-09-26
NO20081314L (no) 2008-03-17
ES2361933T3 (es) 2011-06-24
JP2009506989A (ja) 2009-02-19
GB0517193D0 (en) 2005-09-28
CA2620090A1 (en) 2007-03-01
ATE500826T1 (de) 2011-03-15
EP1917013A1 (de) 2008-05-07
KR20080040022A (ko) 2008-05-07
JP5166267B2 (ja) 2013-03-21
EA016084B1 (ru) 2012-02-28
BRPI0614929A2 (pt) 2011-04-19
CR9807A (es) 2008-07-29
KR101363090B1 (ko) 2014-02-13
MX2008002564A (es) 2008-03-18
MA29774B1 (fr) 2008-09-01
IL189435A0 (en) 2008-08-07
CN101291669A (zh) 2008-10-22
US20090036461A1 (en) 2009-02-05
EA200800655A1 (ru) 2008-08-29
AU2006284077A1 (en) 2007-03-01
ZA200801352B (en) 2009-01-28
US20120196910A1 (en) 2012-08-02

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