DE602006020351D1 - Arylsulfonylchromane als 5-ht6-inhibitoren - Google Patents
Arylsulfonylchromane als 5-ht6-inhibitorenInfo
- Publication number
- DE602006020351D1 DE602006020351D1 DE602006020351T DE602006020351T DE602006020351D1 DE 602006020351 D1 DE602006020351 D1 DE 602006020351D1 DE 602006020351 T DE602006020351 T DE 602006020351T DE 602006020351 T DE602006020351 T DE 602006020351T DE 602006020351 D1 DE602006020351 D1 DE 602006020351D1
- Authority
- DE
- Germany
- Prior art keywords
- arylsulfonylchromane
- inhibitoren
- als
- arylsulfonylchromane als
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73294005P | 2005-11-03 | 2005-11-03 | |
PCT/EP2006/067732 WO2007051735A1 (en) | 2005-11-03 | 2006-10-24 | Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006020351D1 true DE602006020351D1 (en) | 2011-04-07 |
Family
ID=37808173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006020351T Active DE602006020351D1 (en) | 2005-11-03 | 2006-10-24 | Arylsulfonylchromane als 5-ht6-inhibitoren |
Country Status (19)
Country | Link |
---|---|
US (1) | US7754759B2 (de) |
EP (1) | EP2027104B1 (de) |
JP (1) | JP2009514828A (de) |
KR (1) | KR100984897B1 (de) |
CN (1) | CN101300246A (de) |
AR (1) | AR056213A1 (de) |
AT (1) | ATE499355T1 (de) |
AU (1) | AU2006310612A1 (de) |
BR (1) | BRPI0618206A2 (de) |
CA (1) | CA2628173A1 (de) |
DE (1) | DE602006020351D1 (de) |
ES (1) | ES2359735T3 (de) |
IL (1) | IL190868A0 (de) |
NO (1) | NO20081818L (de) |
NZ (1) | NZ567285A (de) |
RU (1) | RU2008115032A (de) |
TW (1) | TWI327914B (de) |
WO (1) | WO2007051735A1 (de) |
ZA (1) | ZA200803422B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8354548B2 (en) * | 2010-02-19 | 2013-01-15 | Bristol-Myers Squibb Company | Glycine chroman-6-sulfonamides for use as inhibitors of diacylglycerol lipase |
CN113200952B (zh) * | 2021-04-13 | 2023-03-10 | 江西师范大学 | 一种串联环化反应合成2-氨基-3,3-二氯代色满酮或2-氨基-3,3-二溴代色满酮的方法 |
Family Cites Families (54)
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DE3901814A1 (de) | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
IL93464A (en) | 1989-02-27 | 1996-10-16 | Lilly Co Eli | 2-Amino-1,2,3,4-Tetrahydronaplanin and 3 aminochromes with a transformed ring, a process for their preparation and pharmaceutical preparations containing them |
US5506192A (en) | 1990-06-07 | 1996-04-09 | Sandoz Ltd. | Substituted phthalides and heterocyclic phthalides |
DE69128477T2 (de) | 1990-07-27 | 1998-07-16 | Chugai Pharmaceutical Co Ltd | Benzopyranderivat |
US5401848A (en) | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
DE4102103A1 (de) | 1991-01-25 | 1992-08-20 | Bayer Ag | Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
US5817693A (en) | 1991-11-05 | 1998-10-06 | Cousins; Russell Donovan | Endothelin receptor antagonists |
ZA93436B (en) | 1992-01-24 | 1993-08-25 | Chugai Pharmaceutical Co Ltd | Benzopyran derivatives |
ATE191716T1 (de) | 1992-08-17 | 2000-04-15 | Chugai Pharmaceutical Co Ltd | Benzopyran und benzoxazin-derivate |
US5374643A (en) | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
US5739135A (en) | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
NZ275151A (en) | 1994-01-31 | 1998-02-26 | Pfizer | 3r*4s*3-[4-(4-fluorophenyl)-4-hydroxy-piperidin-1-yl]-chroman-4 ,7-diol; isomers and salts |
US6150402A (en) | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
US5869478A (en) | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
PL324319A1 (en) | 1995-06-30 | 1998-05-25 | Upjohn Co | 1,6-disubstituted isochromates for fighting against sick headaches |
US5663194A (en) | 1995-07-25 | 1997-09-02 | Mewshaw; Richard E. | Chroman-2-ylmethylamino derivatives |
US5935958A (en) | 1996-07-01 | 1999-08-10 | Schering Corporation | Muscarinic antagonists |
KR20000022380A (ko) | 1996-07-01 | 2000-04-25 | 둘락 노먼 씨. | 무스카린 길항제 |
JP2001501918A (ja) | 1996-08-21 | 2001-02-13 | スミスクライン・ビーチャム・コーポレイション | Il―8レセプターアンタゴニスト |
US6559144B2 (en) | 1997-02-13 | 2003-05-06 | Merck Patent Gesellschaft Mit | Bicyclic amino acids |
DE69839305T2 (de) | 1997-02-27 | 2009-04-09 | Takeda Pharmaceutical Co. Ltd. | Aminderivate, ihre herstellung und verwendung als inhibitoren der produktion von amyloid-beta |
TWI242011B (en) | 1997-03-31 | 2005-10-21 | Eisai Co Ltd | 1,4-substituted cyclic amine derivatives |
DE19754573A1 (de) * | 1997-12-09 | 1999-06-10 | Bayer Ag | Pharmazeutische Zusammensetzung zur Behandlung von Schlaganfall und Schädel-Hirn-Trauma |
ES2144355B1 (es) | 1997-12-30 | 2001-01-01 | Ferrer Int | Compuestos derivados del cromeno. |
FR2778662B1 (fr) * | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6586475B1 (en) | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
EP1136477B1 (de) | 1998-12-04 | 2004-03-10 | Takeda Chemical Industries, Ltd. | Benzofuranderivate, verfahren zu ihrer herstellung und deren verwendungen |
CN100486957C (zh) | 2000-04-03 | 2009-05-13 | 武田药品工业株式会社 | 制备胺衍生物的方法 |
US20040034041A1 (en) | 2000-05-10 | 2004-02-19 | Dashyant Dhanak | Novel anti-infectives |
DE10044091A1 (de) * | 2000-09-07 | 2002-04-04 | Merck Patent Gmbh | Chromanonderivate |
AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
AR036081A1 (es) | 2001-06-07 | 2004-08-11 | Smithkline Beecham Corp | Compuesto de 1,2-dihidroquinolina, su uso para preparar una composicion farmaceutica, metodos para prepararlo y compuestos del acido 2-aminobenzoico n-alquilado de utilidad como intermediarios en dichos metodos |
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CN1561338A (zh) | 2001-10-04 | 2005-01-05 | 惠氏公司 | 作为5-羟基色胺-6配体的苯并二氢吡喃衍生物 |
WO2003029239A1 (en) * | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
WO2003037262A2 (en) | 2001-10-29 | 2003-05-08 | Smithkline Beecham Corporation | Novel anit-infectives |
WO2003099801A1 (en) | 2002-05-24 | 2003-12-04 | Smithkline Beecham Corporation | Novel anti-infectives |
US7943639B2 (en) | 2002-06-20 | 2011-05-17 | Proximagen Limited | Compounds |
SG156524A1 (en) | 2002-06-20 | 2009-11-26 | Biovitrum Ab Publ | New compounds useful for the treatment of obesity, type ii diabetes and cns disorders |
US7902203B2 (en) | 2002-11-01 | 2011-03-08 | Abbott Laboratories, Inc. | Anti-infective agents |
US20040162285A1 (en) | 2002-11-01 | 2004-08-19 | Pratt John K. | Anti-infective agents |
US20050075331A1 (en) | 2003-10-06 | 2005-04-07 | Pratt John K. | Anti-infective agents |
US20040097492A1 (en) | 2002-11-01 | 2004-05-20 | Pratt John K | Anti-infective agents |
WO2004052312A2 (en) | 2002-12-11 | 2004-06-24 | Smithkline Beecham Corporation | Anti-infectives |
WO2004052313A2 (en) | 2002-12-11 | 2004-06-24 | Smithkline Beecham Corporation | Anti-infectives |
WO2004058150A2 (en) | 2002-12-17 | 2004-07-15 | Smithkline Beecham Corporation | Anti-infectives |
WO2005019191A2 (en) | 2003-08-25 | 2005-03-03 | Abbott Laboratories | 1, 1-dioxido-4h-1,2,4-benzothiadiazine derivate und verwandte verbindungen als inhibitoren der hcv polymerase zur behandlung von hepatitis c |
WO2005037223A2 (en) | 2003-10-15 | 2005-04-28 | Brigham And Women's Hospital, Inc. | Methods and compositions for immunomodulation |
WO2005040355A2 (en) | 2003-10-24 | 2005-05-06 | Exelixis, Inc. | Tao kinase modulators and methods of use |
ES2338668T3 (es) | 2004-05-05 | 2010-05-11 | F. Hoffmann-La Roche Ag | Arilsulfonil benzodioxanos utiles para la modulacion del receptor 5-ht6 y del receptor 5-ht2a o ambos. |
US7378415B2 (en) | 2004-09-30 | 2008-05-27 | Roche Palo Alto Llc | Benzoxazine and quinoxaline derivatives and uses thereof |
DK1831159T3 (da) | 2004-12-21 | 2010-03-22 | Hoffmann La Roche | Tetralin og indanderivater samt anvendelser deraf |
-
2006
- 2006-10-24 CN CNA2006800410298A patent/CN101300246A/zh active Pending
- 2006-10-24 RU RU2008115032/04A patent/RU2008115032A/ru not_active Application Discontinuation
- 2006-10-24 NZ NZ567285A patent/NZ567285A/en unknown
- 2006-10-24 BR BRPI0618206-2A patent/BRPI0618206A2/pt not_active IP Right Cessation
- 2006-10-24 CA CA002628173A patent/CA2628173A1/en not_active Abandoned
- 2006-10-24 KR KR1020087013315A patent/KR100984897B1/ko not_active IP Right Cessation
- 2006-10-24 DE DE602006020351T patent/DE602006020351D1/de active Active
- 2006-10-24 JP JP2008538331A patent/JP2009514828A/ja not_active Ceased
- 2006-10-24 AT AT06807516T patent/ATE499355T1/de active
- 2006-10-24 AU AU2006310612A patent/AU2006310612A1/en not_active Abandoned
- 2006-10-24 ES ES06807516T patent/ES2359735T3/es active Active
- 2006-10-24 WO PCT/EP2006/067732 patent/WO2007051735A1/en active Application Filing
- 2006-10-24 EP EP06807516A patent/EP2027104B1/de active Active
- 2006-10-31 TW TW095140241A patent/TWI327914B/zh active
- 2006-11-01 AR ARP060104782A patent/AR056213A1/es unknown
- 2006-11-03 US US11/592,685 patent/US7754759B2/en not_active Expired - Fee Related
-
2008
- 2008-04-14 IL IL190868A patent/IL190868A0/en unknown
- 2008-04-15 NO NO20081818A patent/NO20081818L/no not_active Application Discontinuation
- 2008-04-17 ZA ZA200803422A patent/ZA200803422B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2628173A1 (en) | 2007-05-10 |
NZ567285A (en) | 2010-06-25 |
US20070099908A1 (en) | 2007-05-03 |
BRPI0618206A2 (pt) | 2011-08-23 |
AU2006310612A1 (en) | 2007-05-10 |
ZA200803422B (en) | 2009-09-30 |
US7754759B2 (en) | 2010-07-13 |
ES2359735T3 (es) | 2011-05-26 |
AR056213A1 (es) | 2007-09-26 |
IL190868A0 (en) | 2008-11-03 |
JP2009514828A (ja) | 2009-04-09 |
TWI327914B (en) | 2010-08-01 |
ATE499355T1 (de) | 2011-03-15 |
EP2027104A1 (de) | 2009-02-25 |
CN101300246A (zh) | 2008-11-05 |
KR100984897B1 (ko) | 2010-10-01 |
RU2008115032A (ru) | 2009-12-10 |
NO20081818L (no) | 2008-06-19 |
EP2027104B1 (de) | 2011-02-23 |
KR20080074935A (ko) | 2008-08-13 |
TW200800163A (en) | 2008-01-01 |
WO2007051735A1 (en) | 2007-05-10 |
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