DE602005017152D1 - Neue 2,6-diaminopyridin-3-on-derivate - Google Patents

Neue 2,6-diaminopyridin-3-on-derivate

Info

Publication number
DE602005017152D1
DE602005017152D1 DE602005017152T DE602005017152T DE602005017152D1 DE 602005017152 D1 DE602005017152 D1 DE 602005017152D1 DE 602005017152 T DE602005017152 T DE 602005017152T DE 602005017152 T DE602005017152 T DE 602005017152T DE 602005017152 D1 DE602005017152 D1 DE 602005017152D1
Authority
DE
Germany
Prior art keywords
diaminopyridin
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005017152T
Other languages
English (en)
Inventor
David Joseph Bartkovitz
Xin-Jie Chu
Allen John Lovey
Peter Michael Wovkulich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35385535&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602005017152(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE602005017152D1 publication Critical patent/DE602005017152D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Mobile Radio Communication Systems (AREA)
DE602005017152T 2004-07-15 2005-07-08 Neue 2,6-diaminopyridin-3-on-derivate Active DE602005017152D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58812204P 2004-07-15 2004-07-15
PCT/EP2005/007432 WO2006005548A1 (en) 2004-07-15 2005-07-08 Novel 2,6-diaminopyridine-3-one derivatives

Publications (1)

Publication Number Publication Date
DE602005017152D1 true DE602005017152D1 (de) 2009-11-26

Family

ID=35385535

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005017152T Active DE602005017152D1 (de) 2004-07-15 2005-07-08 Neue 2,6-diaminopyridin-3-on-derivate

Country Status (16)

Country Link
US (1) US7423051B2 (de)
EP (1) EP1771420B1 (de)
JP (1) JP2008505955A (de)
KR (1) KR100853973B1 (de)
CN (1) CN1980893B (de)
AR (1) AR050427A1 (de)
AT (1) ATE445604T1 (de)
AU (1) AU2005261899A1 (de)
BR (1) BRPI0513366A (de)
CA (1) CA2573604A1 (de)
DE (1) DE602005017152D1 (de)
ES (1) ES2330765T3 (de)
MX (1) MX2007000574A (de)
RU (1) RU2385866C2 (de)
TW (1) TW200612929A (de)
WO (1) WO2006005548A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007137196A2 (en) * 2006-05-19 2007-11-29 Threshold Pharmaceuticals, Inc. Tubulin binding anti cancer compounds and prodrugs thereof
EP1900727A1 (de) * 2006-08-30 2008-03-19 Cellzome Ag Aminopyridinderivate als Kinase-Inhibitoren
US8017607B2 (en) 2009-10-14 2011-09-13 Hoffmann-La Roche Inc. N-substituted-pyrrolidines as inhibitors of MDM2-P-53 interactions
AU2020404326A1 (en) * 2019-12-20 2022-08-11 Evopoint Biosciences Co., Ltd. Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof
CA3207392A1 (en) * 2021-02-05 2022-08-11 Xiaoxia Yan Cdk inhibitor
CN113117077B (zh) * 2021-03-04 2022-08-09 西南民族大学 一种用于肿瘤联合治疗的铂基单原子纳米酶及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010082501A (ko) 1997-10-27 2001-08-30 개리 이. 프라이드만 4-아미노티아졸 유도체, 그 제조방법 및 싸이클린-의존성키나아제의 억제제로서의 이용방법
US6262096B1 (en) * 1997-11-12 2001-07-17 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
AU5108000A (en) * 1999-06-10 2001-01-02 Yamanouchi Pharmaceutical Co., Ltd. Novel nitrogen-contaiing heterocyclic derivatives or salts thereof
MXPA02001108A (es) 1999-09-15 2002-08-20 Warner Lambert Co Pieridinonas como inhibidores de la cinasa.
AU1462101A (en) 1999-11-22 2001-06-04 Warner-Lambert Company Quinazolines and their use for inhibiting cyclin-dependent kinase enzymes
WO2001079198A1 (en) 2000-04-18 2001-10-25 Agouron Pharmaceuticals, Inc. Pyrazoles for inhibiting protein kinase
BRPI0407618A (pt) 2003-02-21 2006-02-21 Pfizer derivados de tiazole amino substituidos com cicloalquilo contendo n e composições farmacêuticas para inibição da proliferação celular e métodos para a sua utilização
WO2005051387A1 (en) 2003-11-19 2005-06-09 Janssen Pharmaceutica N.V. Amino substituted pyridinyl methanone compounds useful in treating kinase disorders

Also Published As

Publication number Publication date
AR050427A1 (es) 2006-10-25
RU2385866C2 (ru) 2010-04-10
EP1771420B1 (de) 2009-10-14
CN1980893B (zh) 2011-01-19
AU2005261899A1 (en) 2006-01-19
MX2007000574A (es) 2007-03-07
CA2573604A1 (en) 2006-01-19
KR100853973B1 (ko) 2008-08-25
EP1771420A1 (de) 2007-04-11
RU2007105558A (ru) 2008-08-20
BRPI0513366A (pt) 2008-05-06
CN1980893A (zh) 2007-06-13
KR20070028539A (ko) 2007-03-12
US7423051B2 (en) 2008-09-09
WO2006005548A1 (en) 2006-01-19
ES2330765T3 (es) 2009-12-15
ATE445604T1 (de) 2009-10-15
JP2008505955A (ja) 2008-02-28
US20060014708A1 (en) 2006-01-19
TW200612929A (en) 2006-05-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition