DE602005016317D1 - Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung - Google Patents

Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung

Info

Publication number
DE602005016317D1
DE602005016317D1 DE602005016317T DE602005016317T DE602005016317D1 DE 602005016317 D1 DE602005016317 D1 DE 602005016317D1 DE 602005016317 T DE602005016317 T DE 602005016317T DE 602005016317 T DE602005016317 T DE 602005016317T DE 602005016317 D1 DE602005016317 D1 DE 602005016317D1
Authority
DE
Germany
Prior art keywords
geroprotektiver
antiischämischer
inhibitor
oxidation
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005016317T
Other languages
English (en)
Inventor
Leonid Dmitrievich Smipnov
Michail Arkadievich Ostrovsky
Aleksey Michailovich Sipyagin
Aleksandr Evgenievich Doncov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marvel Lifesciences Ltd
Original Assignee
Marvel Lifesciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marvel Lifesciences Ltd filed Critical Marvel Lifesciences Ltd
Publication of DE602005016317D1 publication Critical patent/DE602005016317D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602005016317T 2004-05-12 2005-07-11 Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung Active DE602005016317D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2004114314/04A RU2276138C2 (ru) 2004-05-12 2004-05-12 Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения
PCT/IB2005/003636 WO2007017713A1 (en) 2004-05-12 2005-07-11 The substance having antioxidant, geroprotective and anti-ischemic activity and method for preparing thereof

Publications (1)

Publication Number Publication Date
DE602005016317D1 true DE602005016317D1 (de) 2009-10-08

Family

ID=36021747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005016317T Active DE602005016317D1 (de) 2004-05-12 2005-07-11 Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung

Country Status (11)

Country Link
US (1) US8044210B2 (de)
EP (1) EP1911746B1 (de)
JP (1) JP2009501712A (de)
CN (1) CN101233110B (de)
AT (1) ATE440819T1 (de)
BR (1) BRPI0520433A2 (de)
CA (1) CA2614857A1 (de)
DE (1) DE602005016317D1 (de)
PL (1) PL1911746T3 (de)
RU (1) RU2276138C2 (de)
WO (1) WO2007017713A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2276138C2 (ru) 2004-05-12 2006-05-10 Марвел Лайф Сайнсез Лтд. Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения
EA011238B1 (ru) * 2007-04-03 2009-02-27 Марвел Лайфсайнсез Лтд. Средство, обладающее противогипоксическим, противоинсультным, улучшающим память действием
ES2408172T3 (es) * 2007-12-18 2013-06-18 Dmitri Valerievich Biryukov 3-hidroxipiridinas sustituidas y composiciones farmacéuticas de las mismas
EA201001326A1 (ru) * 2008-02-19 2011-04-29 Марвел Лайфсайнсез Лтд. Стерильные офтальмологические композиции и способ их получения
EA201001328A1 (ru) * 2008-02-19 2011-04-29 Марвел Лайфсайнсез Лтд. Оральные дозированные композиции и способ их получения
EA201001327A1 (ru) * 2008-02-19 2011-04-29 Марвел Лайфсайнсез Лтд. Инъецируемые составы и способ их получения
WO2014012593A1 (en) 2012-07-19 2014-01-23 HandelsOrt AG Alkyl substituted 3-hydroxypyridines for the treatment of depression
RU2671200C2 (ru) * 2015-12-07 2018-10-30 Закрытое Акционерное Общество "Фармфирма "Сотекс" Способ получения 6-метил-2-этилпиридин-3-ол соли (2S)-2-ацетаминопентандиовой кислоты

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2847926B2 (ja) * 1990-08-01 1999-01-20 トヨタ自動車株式会社 自動変速機の変速制御装置
JPH0496277A (ja) * 1990-08-06 1992-03-27 Fujitsu Ltd 不揮発性半導体記憶装置
RU2070010C1 (ru) * 1993-08-31 1996-12-10 Эдуард Сергеевич Аветисов Средство антиоксидантной защиты сред и тканей глаза
RU2112512C1 (ru) 1995-09-22 1998-06-10 Иванов Евгений Васильевич Биологичеcки активная пищевая добавка "глутапирон", обладающая антиканцерогенным и геропротекторным действием
RU2153872C2 (ru) * 1997-10-15 2000-08-10 Амбалов Юрий Михайлович Способ лечения дифтерии
RU2197199C2 (ru) * 2000-05-12 2003-01-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ лечения амблиопии
JP2002017295A (ja) * 2000-07-05 2002-01-22 Yamagami Suehito 眼疾患改善作用及び眼の機能維持作用を有する健康補助食品
RU2250210C1 (ru) * 2003-07-25 2005-04-20 Институт Проблем Химической Физики Российской Академии Наук (Ипхф Ран) Нитроксисукцинат 2,4,6-триметил-3-оксипиридина и способ его получения
RU2276138C2 (ru) 2004-05-12 2006-05-10 Марвел Лайф Сайнсез Лтд. Вещество, обладающее антиоксидантной, геропротекторной и противоишемической активностью, и способ его получения

Also Published As

Publication number Publication date
BRPI0520433A2 (pt) 2009-05-12
EP1911746A1 (de) 2008-04-16
EP1911746B1 (de) 2009-08-26
RU2276138C2 (ru) 2006-05-10
WO2007017713A1 (en) 2007-02-15
CN101233110A (zh) 2008-07-30
PL1911746T3 (pl) 2010-07-30
CN101233110B (zh) 2011-09-14
ATE440819T1 (de) 2009-09-15
CA2614857A1 (en) 2007-02-15
JP2009501712A (ja) 2009-01-22
US8044210B2 (en) 2011-10-25
US20090198068A1 (en) 2009-08-06

Similar Documents

Publication Publication Date Title
DE602005016317D1 (de) Substanz mit oxidationshemmender, geroprotektiver und antiischämischer wirkung und verfahren zu deren herstellung
DE602005025601D1 (de) Anthranilamide, verfahren zu deren herstellung und diese enthaltende schädlingsbekämpfungsmittel
DE602006015231D1 (de) N-(1-alkyl-2-phenylethyl)carbonsäureamidderivate und deren verwendung als fungizide
ATE497957T1 (de) Pyridinderivate als fungizide verbindungen
ATE424384T1 (de) Imidazolderivate, verfahren zu deren herstellung und deren anwendungen
BR0316902A (pt) Processos para preparar (+)duloxetina e hidrocloreto de (+)duloxetina, sal de ácido quiral e (+)duloxetina, di-p-toluil tartarato de (+)duloxetina, (+)duloxetina e composição farmacêutica
DE60307268D1 (de) Pestizide pyridincarbonsäureamidderivate
TNSN07395A1 (en) Novel phenyl-pyridinyl-piperazine derivatives, a method for the production thereof and pharmaceutical compositions containing said derivatives
Janczewski et al. Synthesis of isothiocyanates using DMT/NMM/TsO− as a new desulfurization reagent
NO20080788L (no) Aripiprazolsalter
EA200801960A1 (ru) Соли дулоксетина
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
IS2016B (is) Nýjar 6-(4-fenýlbútoxý)hexýlamínafleiður og aðferð til að fá salmeteról
ATE386735T1 (de) Substituierte benzoylureidopyridyl-piperidin- und pyrrolidin-carbons urederivate, verfahren zu deren herstellung und deren v erwendung
NO20053997D0 (no) Oligosaccharidderivat
DE602004032346D1 (de) C-glycosylisoflavone mit alkylaminoalkoxylsubstituent, deren herstellung und deren verwendung
DE50303599D1 (de) 3-heterocyclyl-substituierte benzoesäurederivate
ATE267832T1 (de) Substanz gm-95, verfahren zu ihrer herstellung und ihre verwendung
ATE249434T1 (de) Ein verfahren zur herstellung von pyrrolidinon- derivaten
DE60230686D1 (de) Anthelmintische substanz fki-1033 und verfahren zur herstellung davon
ATE242760T1 (de) Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen
TH49398A (th) อนุพันธ์ 2-(แอริลแอลคิลแอมิโน)ไพริมิโดน และอนุพันธ์ 2-(เฮทเทอโรแอริลแอลคิลแอมิโน)ไพริมิโดน
TH85134A (th) อนุพันธ์ไอโซอินโดลีนต่าง ๆ
TH52208A (th) อนุพันธ์ของ n-เฟนิแลมีด และ n-พิริดิแลมีด ต่าง ๆ ชนิดใหม่ วิธีการของการเตรียมอนุพันธ์เหล่านี้ และสารผสมเชิงเภสัชกรรมที่มีอนุพันธ์เหล่านี้อยู่ด้วย
TH104142A (th) อนุพันธ์ 2-เฮเทอโรแอโรอิลลิมิดาโซ[1,2-a]ไพริดีน การเตรียมสารเหล่านี้และการใช้สารเหล่านี้ในการรักษาโรค

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: MARVEL LIFESCIENCES LTD., HARROW, MIDDLESEX, L, GB

8364 No opposition during term of opposition