DE602005012287D1 - Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung - Google Patents

Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung

Info

Publication number
DE602005012287D1
DE602005012287D1 DE602005012287T DE602005012287T DE602005012287D1 DE 602005012287 D1 DE602005012287 D1 DE 602005012287D1 DE 602005012287 T DE602005012287 T DE 602005012287T DE 602005012287 T DE602005012287 T DE 602005012287T DE 602005012287 D1 DE602005012287 D1 DE 602005012287D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
biotinylated hexadecasaccharides
hexadecasaccharides
biotinylated
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005012287T
Other languages
English (en)
Inventor
Philippe Duchaussoy
Jean Pascal Herault
Jean Marc Herbert
Maurice Petitou
Pierre Savi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34948342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602005012287(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Publication of DE602005012287D1 publication Critical patent/DE602005012287D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
DE602005012287T 2004-09-09 2005-09-07 Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung Active DE602005012287D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0409557A FR2874924B1 (fr) 2004-09-09 2004-09-09 Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
PCT/FR2005/002218 WO2006030104A1 (fr) 2004-09-09 2005-09-07 Hexadecasaccharides biotinyles, leur preparation et leur utilisation

Publications (1)

Publication Number Publication Date
DE602005012287D1 true DE602005012287D1 (de) 2009-02-26

Family

ID=34948342

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005012287T Active DE602005012287D1 (de) 2004-09-09 2005-09-07 Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung

Country Status (39)

Country Link
US (3) US20070270342A1 (de)
EP (1) EP1791872B1 (de)
JP (1) JP5108519B2 (de)
KR (1) KR101223364B1 (de)
CN (1) CN101039963B (de)
AR (1) AR051286A1 (de)
AT (1) ATE420118T1 (de)
AU (1) AU2005284080B2 (de)
BR (1) BRPI0515078A (de)
CA (1) CA2577258C (de)
CY (1) CY1109126T1 (de)
DE (1) DE602005012287D1 (de)
DK (1) DK1791872T3 (de)
EA (1) EA012587B1 (de)
EC (1) ECSP077272A (de)
ES (1) ES2320576T3 (de)
FR (1) FR2874924B1 (de)
GT (1) GT200500250A (de)
HK (1) HK1113686A1 (de)
HN (1) HN2005000518A (de)
HR (1) HRP20090180T1 (de)
IL (1) IL181569A (de)
MA (1) MA28859B1 (de)
MX (1) MX2007002875A (de)
MY (1) MY140666A (de)
NI (1) NI200700063A (de)
NO (1) NO20071754L (de)
PA (1) PA8644201A1 (de)
PE (1) PE20060663A1 (de)
PL (1) PL1791872T3 (de)
PT (1) PT1791872E (de)
RS (1) RS50762B (de)
SI (1) SI1791872T1 (de)
SV (1) SV2006002221A (de)
TN (1) TNSN07053A1 (de)
TW (1) TW200612970A (de)
UY (1) UY29102A1 (de)
WO (1) WO2006030104A1 (de)
ZA (1) ZA200702255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2912408A1 (fr) * 2007-02-14 2008-08-15 Sanofi Aventis Sa Heparine comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine,leur procede de preparation,leur utilisation
FR2912409B1 (fr) * 2007-02-14 2012-08-24 Sanofi Aventis Heparines de bas poids moleculaire comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine leur procede de preparation,leur utilisation
EP2233143A1 (de) * 2009-03-24 2010-09-29 Sanofi-Aventis Verwendung von Idrabiotaparinux zur Senkung der Blutungsinzidenz bei einer Thrombosebehandlung
EP2145624A1 (de) * 2008-07-18 2010-01-20 Sanofi-Aventis Verwendung von Idrabiotaparinux zur Senkung der Blutungsinzidenz bei einer Thrombosebehandlung
TW201006479A (en) * 2008-07-18 2010-02-16 Sanofi Aventis Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment
FR2935387B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine
FR2952935B1 (fr) 2009-11-20 2011-12-02 Sanofi Aventis Procede de preparation du n-biotinyl-6-aminocaproate de n succinimidyle

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU563351C (en) 1982-01-15 2003-06-19 Glaxo Group Limited Synthesis of oligosaccharides
EP0300099A1 (de) 1987-07-20 1989-01-25 Akzo N.V. Pentasaccharide
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
ATE190619T1 (de) 1993-09-01 2000-04-15 Akzo Nobel Nv Biskonjugate, die zwei saccharide und einen spacer enthalten
FR2751334B1 (fr) 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2773801B1 (fr) 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
FR2773804B1 (fr) 1998-01-19 2000-02-18 Sanofi Sa Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine

Also Published As

Publication number Publication date
FR2874924A1 (fr) 2006-03-10
RS50762B (sr) 2010-08-31
ZA200702255B (en) 2008-09-25
JP2008512538A (ja) 2008-04-24
ES2320576T3 (es) 2009-05-25
HN2005000518A (es) 2009-06-01
FR2874924B1 (fr) 2006-12-01
HRP20090180T1 (en) 2009-05-31
EP1791872A1 (de) 2007-06-06
US20070270342A1 (en) 2007-11-22
CY1109126T1 (el) 2014-07-02
MY140666A (en) 2010-01-15
US8557968B2 (en) 2013-10-15
NO20071754L (no) 2007-04-02
BRPI0515078A (pt) 2008-07-01
CN101039963A (zh) 2007-09-19
PA8644201A1 (es) 2006-05-16
US20130004551A1 (en) 2013-01-03
PE20060663A1 (es) 2006-08-21
PT1791872E (pt) 2009-03-27
AU2005284080A1 (en) 2006-03-23
EA012587B1 (ru) 2009-10-30
US20100279960A1 (en) 2010-11-04
MX2007002875A (es) 2007-05-16
IL181569A0 (en) 2007-07-04
ECSP077272A (es) 2007-03-29
CN101039963B (zh) 2011-07-27
CA2577258A1 (fr) 2006-03-23
PL1791872T3 (pl) 2009-06-30
SV2006002221A (es) 2006-01-13
EA200700594A1 (ru) 2007-08-31
US8703738B2 (en) 2014-04-22
SI1791872T1 (sl) 2009-06-30
CA2577258C (fr) 2013-05-21
TW200612970A (en) 2006-05-01
TNSN07053A1 (fr) 2008-06-02
KR20070051887A (ko) 2007-05-18
WO2006030104A1 (fr) 2006-03-23
IL181569A (en) 2011-08-31
AR051286A1 (es) 2007-01-03
UY29102A1 (es) 2006-04-28
JP5108519B2 (ja) 2012-12-26
ATE420118T1 (de) 2009-01-15
DK1791872T3 (da) 2009-05-04
GT200500250A (es) 2006-04-10
HK1113686A1 (en) 2008-10-10
AU2005284080B2 (en) 2011-10-13
KR101223364B1 (ko) 2013-01-16
NI200700063A (es) 2008-03-07
EP1791872B1 (de) 2009-01-07
MA28859B1 (fr) 2007-09-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition