DE602005003472D1 - Verfahren zur herstellung von 2-oxo-1-pyrrolidinderivaten durch intramolekulare allylierung - Google Patents
Verfahren zur herstellung von 2-oxo-1-pyrrolidinderivaten durch intramolekulare allylierungInfo
- Publication number
- DE602005003472D1 DE602005003472D1 DE602005003472T DE602005003472T DE602005003472D1 DE 602005003472 D1 DE602005003472 D1 DE 602005003472D1 DE 602005003472 T DE602005003472 T DE 602005003472T DE 602005003472 T DE602005003472 T DE 602005003472T DE 602005003472 D1 DE602005003472 D1 DE 602005003472D1
- Authority
- DE
- Germany
- Prior art keywords
- oxo
- preparation
- pyrrolidine derivatives
- allylation
- intramolecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04013715 | 2004-06-11 | ||
EP04013715 | 2004-06-11 | ||
PCT/EP2005/005689 WO2005121082A1 (en) | 2004-06-11 | 2005-05-26 | Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602005003472D1 true DE602005003472D1 (de) | 2008-01-03 |
DE602005003472T2 DE602005003472T2 (de) | 2008-09-25 |
Family
ID=34925330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005003472T Active DE602005003472T2 (de) | 2004-06-11 | 2005-05-26 | Verfahren zur herstellung von 2-oxo-1-pyrrolidinderivaten durch intramolekulare allylierung |
Country Status (15)
Country | Link |
---|---|
US (1) | US7612215B2 (de) |
EP (1) | EP1758855B1 (de) |
JP (1) | JP4866352B2 (de) |
KR (1) | KR101159870B1 (de) |
CN (1) | CN1964942A (de) |
AU (1) | AU2005251884B2 (de) |
BR (1) | BRPI0511956A (de) |
CA (1) | CA2568700A1 (de) |
DE (1) | DE602005003472T2 (de) |
EA (1) | EA010912B1 (de) |
ES (1) | ES2296177T3 (de) |
IL (1) | IL179650A0 (de) |
MX (1) | MXPA06014201A (de) |
WO (1) | WO2005121082A1 (de) |
ZA (1) | ZA200610274B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007065634A1 (en) * | 2005-12-07 | 2007-06-14 | Ucb Pharma, S.A. | 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses |
US8338621B2 (en) | 2005-12-21 | 2012-12-25 | Ucb S.A. | Process for the preparation of 2-oxo-1-pyrrolidine derivatives |
CN101945647B (zh) * | 2008-03-03 | 2013-01-09 | Ucb医药有限公司 | 药物溶液、制备方法和治疗应用 |
EP3260118B1 (de) | 2008-10-16 | 2021-03-24 | The Johns Hopkins University | Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
EP2968237A4 (de) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion |
AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
SI3431106T1 (sl) | 2014-01-21 | 2021-03-31 | Janssen Pharmaceutica Nv | Kombinacije, ki vsebujejo pozitivne alosterične modulatorje metabotropnega glutamatergičnega receptorja podtipa 2 in njihova uporaba |
DK3096790T3 (da) | 2014-01-21 | 2019-10-07 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
US10925834B2 (en) | 2015-05-22 | 2021-02-23 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
CN115141134A (zh) * | 2021-03-31 | 2022-10-04 | 江西同和药业股份有限公司 | 一种化合物及其制备方法和应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
-
2005
- 2005-05-26 JP JP2007526239A patent/JP4866352B2/ja not_active Expired - Fee Related
- 2005-05-26 ES ES05746202T patent/ES2296177T3/es active Active
- 2005-05-26 CA CA002568700A patent/CA2568700A1/en not_active Abandoned
- 2005-05-26 EP EP05746202A patent/EP1758855B1/de active Active
- 2005-05-26 CN CNA2005800189559A patent/CN1964942A/zh active Pending
- 2005-05-26 DE DE602005003472T patent/DE602005003472T2/de active Active
- 2005-05-26 EA EA200602169A patent/EA010912B1/ru not_active IP Right Cessation
- 2005-05-26 AU AU2005251884A patent/AU2005251884B2/en not_active Ceased
- 2005-05-26 WO PCT/EP2005/005689 patent/WO2005121082A1/en active IP Right Grant
- 2005-05-26 US US11/570,143 patent/US7612215B2/en not_active Expired - Fee Related
- 2005-05-26 MX MXPA06014201A patent/MXPA06014201A/es active IP Right Grant
- 2005-05-26 ZA ZA200610274A patent/ZA200610274B/en unknown
- 2005-05-26 KR KR1020077000546A patent/KR101159870B1/ko not_active IP Right Cessation
- 2005-05-26 BR BRPI0511956-1A patent/BRPI0511956A/pt not_active IP Right Cessation
-
2006
- 2006-11-28 IL IL179650A patent/IL179650A0/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2005121082A1 (en) | 2005-12-22 |
CA2568700A1 (en) | 2005-12-22 |
US7612215B2 (en) | 2009-11-03 |
EP1758855B1 (de) | 2007-11-21 |
JP2008501740A (ja) | 2008-01-24 |
EA010912B1 (ru) | 2008-12-30 |
KR101159870B1 (ko) | 2012-06-25 |
JP4866352B2 (ja) | 2012-02-01 |
US20080125598A1 (en) | 2008-05-29 |
ES2296177T3 (es) | 2008-04-16 |
CN1964942A (zh) | 2007-05-16 |
AU2005251884B2 (en) | 2011-03-24 |
MXPA06014201A (es) | 2007-03-12 |
IL179650A0 (en) | 2007-05-15 |
EA200602169A1 (ru) | 2007-06-29 |
BRPI0511956A (pt) | 2008-01-22 |
EP1758855A1 (de) | 2007-03-07 |
AU2005251884A1 (en) | 2005-12-22 |
KR20070026794A (ko) | 2007-03-08 |
ZA200610274B (en) | 2008-06-25 |
DE602005003472T2 (de) | 2008-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |