DE602004030673D1 - Flüssige oder gefriergetrocknete pharmazeutische zusammensetzung enthaltend fsh und/oder lh, das nichtionische tensid poloxamer 188 und ein antibakterielles mittel - Google Patents

Flüssige oder gefriergetrocknete pharmazeutische zusammensetzung enthaltend fsh und/oder lh, das nichtionische tensid poloxamer 188 und ein antibakterielles mittel

Info

Publication number
DE602004030673D1
DE602004030673D1 DE602004030673T DE602004030673T DE602004030673D1 DE 602004030673 D1 DE602004030673 D1 DE 602004030673D1 DE 602004030673 T DE602004030673 T DE 602004030673T DE 602004030673 T DE602004030673 T DE 602004030673T DE 602004030673 D1 DE602004030673 D1 DE 602004030673D1
Authority
DE
Germany
Prior art keywords
pharmaceutical
poloxamer
freeze
liquid
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004030673T
Other languages
English (en)
Inventor
Fabrizio Samaritani
Piergiorgio Donati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ares Trading SA
Original Assignee
Ares Trading SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33135521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602004030673(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ares Trading SA filed Critical Ares Trading SA
Publication of DE602004030673D1 publication Critical patent/DE602004030673D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE602004030673T 2003-04-02 2004-04-02 Flüssige oder gefriergetrocknete pharmazeutische zusammensetzung enthaltend fsh und/oder lh, das nichtionische tensid poloxamer 188 und ein antibakterielles mittel Expired - Lifetime DE602004030673D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP03100882 2003-04-02
EP03101543 2003-05-27
EP03101828 2003-06-20
PCT/EP2004/050432 WO2004087213A1 (en) 2003-04-02 2004-04-02 Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant

Publications (1)

Publication Number Publication Date
DE602004030673D1 true DE602004030673D1 (de) 2011-02-03

Family

ID=33135521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004030673T Expired - Lifetime DE602004030673D1 (de) 2003-04-02 2004-04-02 Flüssige oder gefriergetrocknete pharmazeutische zusammensetzung enthaltend fsh und/oder lh, das nichtionische tensid poloxamer 188 und ein antibakterielles mittel

Country Status (25)

Country Link
US (1) US7741268B2 (de)
EP (1) EP1610822B2 (de)
JP (1) JP4699991B2 (de)
KR (1) KR101105486B1 (de)
AR (1) AR043972A1 (de)
AT (1) ATE492292T2 (de)
AU (1) AU2004226666B9 (de)
BR (1) BRPI0409532B8 (de)
CA (1) CA2518903C (de)
CY (1) CY1111291T1 (de)
DE (1) DE602004030673D1 (de)
DK (1) DK1610822T4 (de)
EA (1) EA012565B1 (de)
HK (1) HK1086503A1 (de)
HR (1) HRP20100727T4 (de)
IL (1) IL171151A (de)
ME (1) ME00217B (de)
MX (1) MXPA05010635A (de)
NO (1) NO330214B1 (de)
NZ (1) NZ542247A (de)
PL (1) PL1610822T5 (de)
PT (1) PT1610822E (de)
RS (2) RS57872B1 (de)
SI (1) SI1610822T2 (de)
WO (1) WO2004087213A1 (de)

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KR101105871B1 (ko) * 2005-09-27 2012-01-16 주식회사 엘지생명과학 인 난포자극호르몬의 안정한 용액 제형
AU2008320844B2 (en) * 2007-11-01 2013-08-29 Merck Serono S.A. LH liquid formulations
PL2249869T3 (pl) * 2008-02-08 2012-02-29 Theramex Hq Uk Ltd Ciekły preparat FSH
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
CN102309747B (zh) * 2008-09-17 2013-04-17 上海天伟生物制药有限公司 高纯度绝经期促性腺素冻干针剂
AU2009312235B2 (en) * 2008-11-04 2014-01-16 Aska Pharmaceutical Co., Ltd. Aqueous composition containing follicle-stimulating hormone
ME02277B (me) 2009-04-01 2016-02-20 Ratiopharm Gmbh Postupak za prečišćavanje rekombinantnog fsh
EP2325194A1 (de) 2009-11-24 2011-05-25 Glycotope GmbH Verfahren zur Reinigung von Glykoproteinen
WO2011076117A1 (zh) * 2009-12-22 2011-06-30 上海天伟生物制药有限公司 绝经期促性腺素组合物
WO2012127500A2 (en) * 2011-03-11 2012-09-27 Sanzyme Limited Composition for spermatogenesis
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
JP6166470B2 (ja) * 2013-11-12 2017-07-19 カディラ ヘルスケア リミティド ゴナドトロピンのための新規製剤
JP6647220B2 (ja) * 2014-05-23 2020-02-14 インスティトゥート・マッソーネ・エセ・ア Hmg−up(超高純度グレードのヒト閉経期ゴナドトロピン)を得るための方法及び夾雑物を含まない組成物
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals

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Also Published As

Publication number Publication date
NZ542247A (en) 2008-03-28
PL1610822T5 (pl) 2019-05-31
PT1610822E (pt) 2011-01-05
HRP20100727T4 (hr) 2018-11-16
CY1111291T1 (el) 2015-08-05
BRPI0409532B1 (pt) 2019-09-17
EP1610822B1 (de) 2010-12-22
BRPI0409532A (pt) 2006-04-18
ME00217B (me) 2011-02-10
HK1086503A1 (en) 2006-09-22
US7741268B2 (en) 2010-06-22
KR101105486B1 (ko) 2012-01-13
RS57872B1 (sr) 2018-12-31
WO2004087213A8 (en) 2005-03-17
EP1610822B2 (de) 2018-09-19
DK1610822T3 (da) 2011-01-31
RS20050737A (en) 2007-11-15
HRP20100727T1 (en) 2011-02-28
NO330214B1 (no) 2011-03-07
JP4699991B2 (ja) 2011-06-15
PL1610822T3 (pl) 2011-06-30
DK1610822T4 (en) 2019-01-14
AU2004226666B2 (en) 2009-09-03
KR20050110037A (ko) 2005-11-22
AU2004226666A1 (en) 2004-10-14
AR043972A1 (es) 2005-08-17
WO2004087213A1 (en) 2004-10-14
EP1610822A1 (de) 2006-01-04
EA012565B1 (ru) 2009-10-30
BRPI0409532B8 (pt) 2021-05-25
CA2518903C (en) 2013-02-05
EA200501531A1 (ru) 2006-06-30
NO20054982L (no) 2005-10-26
SI1610822T2 (sl) 2018-12-31
MEP31708A (en) 2010-10-10
IL171151A (en) 2014-11-30
CA2518903A1 (en) 2004-10-14
ATE492292T2 (de) 2011-01-15
SI1610822T1 (sl) 2011-02-28
MXPA05010635A (es) 2005-12-12
JP2006522072A (ja) 2006-09-28
AU2004226666B9 (en) 2010-04-08
US20060147480A1 (en) 2006-07-06

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