DE602004029503D1 - Plasmid der 2-mikron-familie und verwendung davon - Google Patents

Plasmid der 2-mikron-familie und verwendung davon

Info

Publication number
DE602004029503D1
DE602004029503D1 DE602004029503T DE602004029503T DE602004029503D1 DE 602004029503 D1 DE602004029503 D1 DE 602004029503D1 DE 602004029503 T DE602004029503 T DE 602004029503T DE 602004029503 T DE602004029503 T DE 602004029503T DE 602004029503 D1 DE602004029503 D1 DE 602004029503D1
Authority
DE
Germany
Prior art keywords
plasmid
gene
micron family
last
family
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004029503T
Other languages
English (en)
Inventor
Darrell Sleep
Christopher John Finnis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes Biopharma DK AS
Original Assignee
Novozymes Biopharma DK AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biopharma DK AS filed Critical Novozymes Biopharma DK AS
Publication of DE602004029503D1 publication Critical patent/DE602004029503D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DE602004029503T 2003-12-23 2004-12-23 Plasmid der 2-mikron-familie und verwendung davon Active DE602004029503D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329722.3A GB0329722D0 (en) 2003-12-23 2003-12-23 Modified plasmid and use thereof
PCT/GB2004/005435 WO2005061719A1 (en) 2003-12-23 2004-12-23 2-micron family plasmid and use thereof

Publications (1)

Publication Number Publication Date
DE602004029503D1 true DE602004029503D1 (de) 2010-11-18

Family

ID=30776295

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004029503T Active DE602004029503D1 (de) 2003-12-23 2004-12-23 Plasmid der 2-mikron-familie und verwendung davon

Country Status (14)

Country Link
US (1) US8252551B2 (de)
EP (1) EP1711602B1 (de)
JP (1) JP4964596B2 (de)
KR (1) KR101298157B1 (de)
CN (2) CN1922326B (de)
AT (1) ATE483812T1 (de)
AU (1) AU2004303597C1 (de)
CA (1) CA2551496C (de)
DE (1) DE602004029503D1 (de)
DK (1) DK1711602T3 (de)
GB (2) GB0329722D0 (de)
NZ (1) NZ548154A (de)
WO (1) WO2005061719A1 (de)
ZA (1) ZA200605589B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066085A1 (en) * 2002-02-07 2003-08-14 Delta Biotechnology Limited Albumin-fused anti-angiogenesis peptides
US9057061B2 (en) 2003-12-23 2015-06-16 Novozymes Biopharma Dk A/S Gene expression technique
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
EP1766002B1 (de) * 2004-06-21 2015-11-18 Novozymes A/S Mehrere kopien wenigstens zweier offener leserrahmen stabil erhalten in gleicher orientierung
GB0512707D0 (en) * 2005-06-22 2005-07-27 Delta Biotechnology Ltd Gene expression technique
EP2594583A1 (de) 2007-08-08 2013-05-22 Novozymes Biopharma DK A/S Transferrinvarianten und Konjugate
JP2012516878A (ja) 2009-02-06 2012-07-26 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ 精製プロセス
CN102317315A (zh) 2009-02-11 2012-01-11 诺维信生物制药丹麦公司 白蛋白变体和缀合物
JP2013509170A (ja) 2009-10-30 2013-03-14 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ アルブミン変異体
WO2011124718A1 (en) 2010-04-09 2011-10-13 Novozymes A/S Albumin derivatives and variants
CN101974547B (zh) * 2010-07-30 2012-06-27 天津大学 含FLP的pBBR1MCS-2重组质粒及运动发酵单胞菌基因组DNA修饰的方法
WO2012033832A2 (en) 2010-09-07 2012-03-15 Butamax(Tm) Advanced Biofuels Llc Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US20120088271A1 (en) * 2010-09-30 2012-04-12 Codexis, Inc. Use of an Endogenous 2-Micron Yeast Plasmid for Gene Over Expression
CN103827304B (zh) 2011-03-24 2018-04-17 布特马斯先进生物燃料有限责任公司 用于异丁醇生产的宿主细胞和方法
EP2780364A2 (de) 2011-11-18 2014-09-24 Eleven Biotherapeutics, Inc. Proteine mit verbesserter halbwertzeit und anderen eigenschaften
BR112014016005A8 (pt) 2011-12-30 2017-07-04 Butamax Advanced Biofuels Llc alterações genéticas para produção de butanol
EP2808388B1 (de) 2012-01-23 2019-03-13 AGC Inc. Expressionsvektor und verfahren zur herstellung von protein
KR20140136934A (ko) 2012-03-16 2014-12-01 노보자임스 바이오파마 디케이 에이/에스 알부민 변이체
WO2013177063A1 (en) * 2012-05-21 2013-11-28 University Of Southern California Uses of protein precursors as prodrugs
BR112015010318A2 (pt) 2012-11-08 2017-08-22 Albumedix As Variantes de albumina
CN103898142B (zh) * 2014-03-04 2016-03-02 北京理工大学 一种硫醇过氧化物酶提高毕赤酵母外源蛋白质表达量的方法
WO2015176641A1 (zh) * 2014-05-21 2015-11-26 中国科学院上海生命科学研究院 一种促进重组极端耐热α-淀粉酶可溶性表达的方法
CN104946659A (zh) * 2015-03-27 2015-09-30 杭州北斗生物技术有限公司 重组人生长激素的制备方法及其peg化修饰物的制备方法
CA2989966C (en) 2015-08-20 2024-04-30 Albumedix A/S Albumin variants and conjugates
CN108431204A (zh) * 2015-12-22 2018-08-21 阿尔布梅迪克斯医疗有限公司 改良的表达蛋白质的菌株
CN109153985B (zh) * 2016-01-12 2022-02-22 Ａｇｃ株式会社 转化体、以及转铁蛋白的制造方法
CN107367619A (zh) * 2017-08-30 2017-11-21 福建师范大学 Tcp1蛋白在制备乳腺癌术后预后评估试剂盒中的应用、乳腺癌预后评估试剂盒及方法
DK3775222T3 (da) * 2018-03-26 2024-02-19 Novozymes As Chaperoneproteiner fra svampe
CN110184292B (zh) * 2019-06-17 2023-01-20 湖北大学 一种利用分子伴侣提高酵母细胞表面展示功能性Infliximab Fab片段的方法
CN112680371A (zh) * 2019-10-18 2021-04-20 广东利世康低碳科技有限公司 一种水解餐厨垃圾中蛋白成分的产朊假丝酵母双基因共表达菌株及其构建方法
CN110592090A (zh) * 2019-10-30 2019-12-20 福建师范大学 Ssa4基因启动子及利用该启动子驱动外源基因转录的毕赤酵母表达载体
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
CN112501141A (zh) * 2020-10-22 2021-03-16 重庆中元汇吉生物技术有限公司 一种增加人甲状腺过氧化物酶产量的试剂和表达方法
CN114410496B (zh) * 2022-02-16 2023-10-03 江南大学 一种提高毕赤酵母外源蛋白产量的方法
CN114957488A (zh) * 2022-05-19 2022-08-30 中国科学院生物物理研究所 芳香烃受体蛋白稳定高效表达的方法及其应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019919D0 (en) 1990-09-12 1990-10-24 Delta Biotechnology Ltd Purification of proteins
US4302386A (en) * 1978-08-25 1981-11-24 The Ohio State University Antigenic modification of polypeptides
NZ199722A (en) 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
IL66614A (en) 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
GB8620926D0 (en) 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
GB2210621B (en) * 1987-04-09 1990-11-21 Delta Biotechnology Ltd Two micron yeast plasmid vector
IL86455A0 (en) 1987-06-01 1988-11-15 Takeda Chemical Industries Ltd Polypeptide and production thereof
IL88326A (en) 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
EP0398944A4 (en) 1988-02-05 1991-09-11 Commonwealth Scientific And Industrial Research Organisation Gene expression system (particularly for rotavirus vp7 protein) involving a foreign signal peptide and optionally a transmembrane anchor sequence
HU213571B (en) 1988-07-23 1997-08-28 Delta Biotechnology Ltd Process for producing peptides and dna sequences
US5759802A (en) 1988-10-26 1998-06-02 Tonen Corporation Production of human serum alubumin A
GB8909916D0 (en) 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
GB8927480D0 (en) 1989-12-05 1990-02-07 Delta Biotechnology Ltd Mutant fungal strain detection and new promoter
JP3230091B2 (ja) 1990-06-25 2001-11-19 ウェルファイド株式会社 ヒト血清アルブミンの着色抑制方法
WO1992001069A1 (en) * 1990-07-13 1992-01-23 Transkaryotic Therapies, Inc. Library screening method
GB2249096A (en) * 1990-10-11 1992-04-29 Ciba Geigy Saccharomyces cerevisiae strains lacking carboxypeptidase yscY activity for expression of proteins at high yields
WO1992013550A1 (en) * 1991-02-08 1992-08-20 The University Of Vermont And State Agricultural College Recombinant transferrins, transferrin half-molecules and mutants thereof
EP0501914A1 (de) * 1991-02-25 1992-09-02 Ciba-Geigy Ag Verbesserte Hefe-Vektorer
EP0509841A3 (en) 1991-04-18 1993-08-18 Tonen Corporation Co-expression system of protein disulfide isomerase gene and useful polypeptide gene and process for producing the polypeptide using its system
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
US6291205B1 (en) * 1992-06-12 2001-09-18 Merck & Co., Inc. Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae
WO1994003617A1 (en) 1992-07-29 1994-02-17 Unilever N.V. Process for producing anti-freeze peptides
DE4244915C2 (de) 1992-08-14 1998-12-03 Widmar Prof Dr Tanner DNA-Moleküle codierend Proteine, die an der O-Glykosylierung von Proteinen beteiligt sind
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
DE69329202T2 (de) * 1992-10-02 2001-03-29 Res Corp Technologies Inc Methoden der erhöhung der sekretion von überexpremierten proteinen
GB9404270D0 (en) 1994-03-05 1994-04-20 Delta Biotechnology Ltd Yeast strains and modified albumins
GB9411356D0 (en) 1994-06-07 1994-07-27 Delta Biotechnology Ltd Yeast strains
JP3945866B2 (ja) * 1996-09-04 2007-07-18 サントリー株式会社 メタノール酵母由来のプロテインジスルフィドイソメラーゼ遺伝子
GB9703406D0 (en) * 1997-02-19 1997-04-09 Chiron Spa Expression of heterologous proteins
EP0980436A1 (de) 1997-06-13 2000-02-23 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Erhöhte produktion von proteinen durch verwendung von chaperonproteinen
GB9713412D0 (en) 1997-06-26 1997-08-27 Delta Biotechnology Ltd Improved protein expression strains
BR9714828A (pt) * 1997-09-05 2000-07-25 Pentapharm Ag Vetor de expressão para a produção de um polipeptìdeo na levedura, cepa de levedura, e, processos para a produção de um vetor de expressão, para a produção de uma cepa de levedura e para a produção de um polipeptìdeo em uma cepa de levedura
IT1306207B1 (it) 1999-01-15 2001-05-30 Biopolo S C A R L Produzione di proteine eterologhe da zygosaccharomyces bailii.
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
CA2405709A1 (en) 2000-04-12 2001-10-25 Human Genome Sciences, Inc. Albumin fusion proteins
US7176278B2 (en) * 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20030226155A1 (en) * 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
WO2003066085A1 (en) 2002-02-07 2003-08-14 Delta Biotechnology Limited Albumin-fused anti-angiogenesis peptides
KR20050065519A (ko) 2002-08-07 2005-06-29 델타 바이오테크놀로지 리미티드 알부민-융합 섬모 신경영양 인자
DE10252245A1 (de) 2002-11-07 2004-05-27 Prof. Dr. Danilo Porro Università degli Studi di Milano-Bicocca Dipartimento die Biotechnologie e Bioscienze Verfahren zur Expression und Sekretion von Proteinen mittels der nicht-konventionellen Hefe Zygosaccharomyces bailii
US6939676B2 (en) * 2002-12-30 2005-09-06 The United States Of America As Represented By The Secretary Of Argriculture Selection procedure for identifying transgenic cells, embryos, and plants without the use of antibiotics
GB0305989D0 (en) 2003-03-15 2003-04-23 Delta Biotechnology Ltd Agent
US9057061B2 (en) 2003-12-23 2015-06-16 Novozymes Biopharma Dk A/S Gene expression technique
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
GB0329681D0 (en) * 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
GB0402660D0 (en) 2004-02-06 2004-03-10 Medical Res Council Heterologous protein expression
JP4988337B2 (ja) * 2004-05-21 2012-08-01 タカラバイオ株式会社 ポリペプチドの製造方法

Also Published As

Publication number Publication date
GB2424888A (en) 2006-10-11
AU2004303597C1 (en) 2009-05-14
GB0614610D0 (en) 2006-08-30
CN1922326B (zh) 2011-02-09
CN101128587A (zh) 2008-02-20
GB2424888B (en) 2008-03-26
DK1711602T3 (da) 2011-01-31
EP1711602A1 (de) 2006-10-18
JP4964596B2 (ja) 2012-07-04
WO2005061719A1 (en) 2005-07-07
AU2004303597A1 (en) 2005-07-07
GB0329722D0 (en) 2004-01-28
US8252551B2 (en) 2012-08-28
US20080261861A1 (en) 2008-10-23
CN1922326A (zh) 2007-02-28
AU2004303597B2 (en) 2008-09-25
CN101128587B (zh) 2014-02-12
CA2551496A1 (en) 2005-07-07
EP1711602B1 (de) 2010-10-06
KR20070004585A (ko) 2007-01-09
ZA200605589B (en) 2007-12-27
ATE483812T1 (de) 2010-10-15
KR101298157B1 (ko) 2013-08-21
NZ548154A (en) 2009-05-31
CA2551496C (en) 2014-12-09
JP2007515961A (ja) 2007-06-21

Similar Documents

Publication Publication Date Title
DE602004029503D1 (de) Plasmid der 2-mikron-familie und verwendung davon
DE60135229D1 (de) T1r-geschmacksrezeptoren und ihre kodierenden gene
DE502006002198D1 (de) Ur erhöhung der permeabilität von unterirdischen, teinsformationen und zum lösen von carbonatischen und/oder carbonathaltigen verunreinigungen bei der erdölförderung
EP1649006A4 (de) Exo-spezifische amylase-polypeptide, diese polypeptide codierende nukleinsäuren und verwendungen davon
DE60325892D1 (de) Stellungs- und verwendungsverfahren
SG130189A1 (en) Substituted indole-o-glucosides
ATE477367T1 (de) Gewebeweichmachende dosierer und anwendungen
MY145160A (en) A composition and method for making a proppant
NO20055130D0 (no) Aminocykloheksyleter-forbindelser og deres anvendelse
ATE507822T1 (de) Stabilisierte zusammensetzungen von faktor-vii- polypeptiden
DE60305611D1 (de) Tonzusammensetzung, Verfahren und Anwendungen damit
DE60137307D1 (de) Substituierte sapogenine und ihre verwendung
CY1106391T1 (el) 2-υποκατεστημενες πυριμιδινες
DE60332096D1 (de) Mikrosatellitenmarker in form von mononukleotidwiederholungen zur detektion von mikrosatelliteninstabilität
ATE254474T1 (de) Impfstoffzusammensetzung gegen herpes simplex virus und methoden zur verwendung
DE60230456D1 (de) Faktor-viii-polypeptide auf hohem expressionsnivea und verwendungsverfahren
MXPA03010158A (es) Sulfonamidas.
DE602004031527D1 (de) Kombination von serotonin-wiederaufnahme-hemmern und agomelatin
GB2399083B (en) flexible cementing compositions and methods for high-temperature wells
NO20060420L (no) 2-aminobenzoylderivater
ATE514431T1 (de) Allergie-vakzine-zusammensetzung, herstellungsverfahren dafür und ihre verwendung bei der behandlung von allergien
NO20024664L (no) Sammensetning basert pÕ sulfid av sjeldent jordmetall med forbedret kjemisk stabilitet, fremgangsmÕte for fremstilling deravog anvendelse derav som pigment
DE602005015823D1 (de) Veränderung der wurzelstruktur während der pflanzenentwicklung
ATE279923T1 (de) Urotensin-ii rezeptorantagonisten
ATE408013T1 (de) Infektiöses cdna klon des gb-virus b und dessen verwendungen