DE602004028830D1 - Verfahren zur herstellung von kristallinem dexloxiglumid - Google Patents

Verfahren zur herstellung von kristallinem dexloxiglumid

Info

Publication number
DE602004028830D1
DE602004028830D1 DE602004028830T DE602004028830T DE602004028830D1 DE 602004028830 D1 DE602004028830 D1 DE 602004028830D1 DE 602004028830 T DE602004028830 T DE 602004028830T DE 602004028830 T DE602004028830 T DE 602004028830T DE 602004028830 D1 DE602004028830 D1 DE 602004028830D1
Authority
DE
Germany
Prior art keywords
dexloxiglumide
preparing crystalline
crystalline dexloxiglumide
morphological
favor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004028830T
Other languages
German (de)
English (en)
Inventor
Francesco Makovec
Lucio Claudio Rovati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rottapharm SpA
Original Assignee
Rottapharm SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rottapharm SpA filed Critical Rottapharm SpA
Publication of DE602004028830D1 publication Critical patent/DE602004028830D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE602004028830T 2003-06-23 2004-06-21 Verfahren zur herstellung von kristallinem dexloxiglumid Expired - Lifetime DE602004028830D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000474A ITTO20030474A1 (it) 2003-06-23 2003-06-23 Procedimento per la preparazione di dexloxiglumide
PCT/IB2004/002208 WO2004113271A2 (en) 2003-06-23 2004-06-21 A method for the preparation of crystalline dexloxiglumide

Publications (1)

Publication Number Publication Date
DE602004028830D1 true DE602004028830D1 (de) 2010-10-07

Family

ID=33524063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004028830T Expired - Lifetime DE602004028830D1 (de) 2003-06-23 2004-06-21 Verfahren zur herstellung von kristallinem dexloxiglumid

Country Status (12)

Country Link
US (1) US7662994B2 (https=)
EP (1) EP1646607B1 (https=)
JP (1) JP5197955B2 (https=)
AT (1) ATE478839T1 (https=)
AU (1) AU2004249526B2 (https=)
CA (1) CA2529018C (https=)
DE (1) DE602004028830D1 (https=)
DK (1) DK1646607T3 (https=)
ES (1) ES2351662T3 (https=)
IT (1) ITTO20030474A1 (https=)
PT (1) PT1646607E (https=)
WO (1) WO2004113271A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7863330B2 (en) * 2006-06-14 2011-01-04 Rottapharm S.P.A. Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217123B (it) * 1987-02-05 1990-03-14 Rotta Research Lab Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
ES2078447T3 (es) * 1990-06-15 1995-12-16 Merck & Co Inc Un procedimiento de cristalizacion para mejorar la estructura y el tamaño de los cristales.
US7122083B2 (en) * 2002-04-02 2006-10-17 E. I. Du Pont De Nemours And Company Apparatus and process used in growing crystals

Also Published As

Publication number Publication date
DK1646607T3 (da) 2010-11-22
WO2004113271A8 (en) 2005-05-06
ITTO20030474A1 (it) 2004-12-24
ES2351662T3 (es) 2011-02-09
WO2004113271A2 (en) 2004-12-29
HK1089750A1 (en) 2006-12-08
PT1646607E (pt) 2010-10-12
WO2004113271A3 (en) 2005-01-27
EP1646607A2 (en) 2006-04-19
AU2004249526A1 (en) 2004-12-29
CA2529018A1 (en) 2004-12-29
US7662994B2 (en) 2010-02-16
CA2529018C (en) 2013-05-28
AU2004249526B2 (en) 2011-02-24
EP1646607B1 (en) 2010-08-25
JP2007521253A (ja) 2007-08-02
ATE478839T1 (de) 2010-09-15
JP5197955B2 (ja) 2013-05-15
US20060154987A1 (en) 2006-07-13

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