DK1646607T3 - Fremgangsmåde til fremstilling af krystallinsk dexloxiglumid - Google Patents

Fremgangsmåde til fremstilling af krystallinsk dexloxiglumid

Info

Publication number
DK1646607T3
DK1646607T3 DK04743871.8T DK04743871T DK1646607T3 DK 1646607 T3 DK1646607 T3 DK 1646607T3 DK 04743871 T DK04743871 T DK 04743871T DK 1646607 T3 DK1646607 T3 DK 1646607T3
Authority
DK
Denmark
Prior art keywords
preparation
dexloxiglumide
crystalline
crystalline dexloxiglumide
morphological
Prior art date
Application number
DK04743871.8T
Other languages
English (en)
Inventor
Lucio Claudio Rovati
Francesco Makovec
Original Assignee
Rottapharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rottapharm Spa filed Critical Rottapharm Spa
Application granted granted Critical
Publication of DK1646607T3 publication Critical patent/DK1646607T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
DK04743871.8T 2003-06-23 2004-06-21 Fremgangsmåde til fremstilling af krystallinsk dexloxiglumid DK1646607T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000474A ITTO20030474A1 (it) 2003-06-23 2003-06-23 Procedimento per la preparazione di dexloxiglumide
PCT/IB2004/002208 WO2004113271A2 (en) 2003-06-23 2004-06-21 A method for the preparation of crystalline dexloxiglumide

Publications (1)

Publication Number Publication Date
DK1646607T3 true DK1646607T3 (da) 2010-11-22

Family

ID=33524063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04743871.8T DK1646607T3 (da) 2003-06-23 2004-06-21 Fremgangsmåde til fremstilling af krystallinsk dexloxiglumid

Country Status (13)

Country Link
US (1) US7662994B2 (da)
EP (1) EP1646607B1 (da)
JP (1) JP5197955B2 (da)
AT (1) ATE478839T1 (da)
AU (1) AU2004249526B2 (da)
CA (1) CA2529018C (da)
DE (1) DE602004028830D1 (da)
DK (1) DK1646607T3 (da)
ES (1) ES2351662T3 (da)
HK (1) HK1089750A1 (da)
IT (1) ITTO20030474A1 (da)
PT (1) PT1646607E (da)
WO (1) WO2004113271A2 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7863330B2 (en) * 2006-06-14 2011-01-04 Rottapharm S.P.A. Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217123B (it) * 1987-02-05 1990-03-14 Rotta Research Lab Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
IE67187B1 (en) * 1990-06-15 1996-03-06 Merck & Co Inc A crystallization method to improve crystal structure and size
CN1658936A (zh) * 2002-04-02 2005-08-24 纳幕尔杜邦公司 生长晶体中使用的装置和方法

Also Published As

Publication number Publication date
ES2351662T3 (es) 2011-02-09
EP1646607B1 (en) 2010-08-25
US20060154987A1 (en) 2006-07-13
CA2529018A1 (en) 2004-12-29
AU2004249526B2 (en) 2011-02-24
AU2004249526A1 (en) 2004-12-29
HK1089750A1 (en) 2006-12-08
EP1646607A2 (en) 2006-04-19
US7662994B2 (en) 2010-02-16
CA2529018C (en) 2013-05-28
JP5197955B2 (ja) 2013-05-15
WO2004113271A3 (en) 2005-01-27
PT1646607E (pt) 2010-10-12
WO2004113271A2 (en) 2004-12-29
DE602004028830D1 (de) 2010-10-07
WO2004113271A8 (en) 2005-05-06
JP2007521253A (ja) 2007-08-02
ATE478839T1 (de) 2010-09-15
ITTO20030474A1 (it) 2004-12-24

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