DE602004026872D1 - Anti-hgf-r-antikörper und deren verwendung - Google Patents

Anti-hgf-r-antikörper und deren verwendung

Info

Publication number
DE602004026872D1
DE602004026872D1 DE602004026872T DE602004026872T DE602004026872D1 DE 602004026872 D1 DE602004026872 D1 DE 602004026872D1 DE 602004026872 T DE602004026872 T DE 602004026872T DE 602004026872 T DE602004026872 T DE 602004026872T DE 602004026872 D1 DE602004026872 D1 DE 602004026872D1
Authority
DE
Germany
Prior art keywords
antibodies
hgf
relates
hfg
secretes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004026872T
Other languages
English (en)
Inventor
Maria Giovanna Prat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNI DEGLI STUDI DEL PIEMONTE O
Universita degli Studi del Piemonte Orientale -Amedeo Avogadro
Original Assignee
UNI DEGLI STUDI DEL PIEMONTE O
Universita degli Studi del Piemonte Orientale -Amedeo Avogadro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNI DEGLI STUDI DEL PIEMONTE O, Universita degli Studi del Piemonte Orientale -Amedeo Avogadro filed Critical UNI DEGLI STUDI DEL PIEMONTE O
Publication of DE602004026872D1 publication Critical patent/DE602004026872D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE602004026872T 2003-06-05 2004-06-01 Anti-hgf-r-antikörper und deren verwendung Expired - Lifetime DE602004026872D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001127A ITMI20031127A1 (it) 2003-06-05 2003-06-05 Anticorpi anti-hgf-r e loro uso
PCT/EP2004/050976 WO2004108766A2 (en) 2003-06-05 2004-06-01 Anti-hgf-r antibodies and their use

Publications (1)

Publication Number Publication Date
DE602004026872D1 true DE602004026872D1 (de) 2010-06-10

Family

ID=30131145

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004026872T Expired - Lifetime DE602004026872D1 (de) 2003-06-05 2004-06-01 Anti-hgf-r-antikörper und deren verwendung

Country Status (8)

Country Link
US (1) US7556804B2 (de)
EP (1) EP1641828B1 (de)
AT (1) ATE466031T1 (de)
CA (1) CA2524329A1 (de)
DE (1) DE602004026872D1 (de)
DK (1) DK1641828T3 (de)
IT (1) ITMI20031127A1 (de)
WO (1) WO2004108766A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
SG175078A1 (en) 2009-04-07 2011-11-28 Roche Glycart Ag Bispecific anti-erbb-1/anti-c-met antibodies
CN102378768A (zh) 2009-04-07 2012-03-14 罗氏格黎卡特股份公司 双特异性抗-ErbB-3/抗-c-Met抗体
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도
KR101748707B1 (ko) * 2009-11-27 2017-06-20 삼성전자주식회사 ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그를 이용한 암 진단용 키트
ITTO20091020A1 (it) * 2009-12-21 2011-06-22 Uni Degli Studi Del Piemonte Orientale Ame "cardiomyocytes anti-apoptotic molecules, products and compositions thereof"
KR102059663B1 (ko) 2010-03-10 2019-12-26 젠맵 에이/에스 Ｃ―ｍｅｔ에 대한 모노클로날 항체
ES2594493T3 (es) 2010-11-03 2016-12-20 arGEN-X BV Anticuerpos anti-c-Met
EP2748197A2 (de) 2011-08-26 2014-07-02 Merrimack Pharmaceuticals, Inc. Fc-bispezifische tandem-antikörper
WO2013043452A1 (en) 2011-09-20 2013-03-28 Eli Lilly And Company Anti-c-met antibodies
EP2773660A2 (de) 2011-11-03 2014-09-10 Argen-X B.V. Chimäre mensch-kamel-antigene und ihre verwendung
KR101910601B1 (ko) 2011-12-22 2018-10-23 삼성전자주식회사 면역원성이 제거된 항 ｃ-Ｍｅｔ 인간화 항체 및 그의 용도
EP2727941A1 (de) 2012-11-05 2014-05-07 MAB Discovery GmbH Verfahren zur Herstellung multispezifischer Antikörper
EP2914629A1 (de) 2012-11-05 2015-09-09 MAB Discovery GmbH Verfahren zur herstellung multispezifischer antikörper
WO2014138449A1 (en) 2013-03-06 2014-09-12 Merrimack Pharmaceuticals, Inc. Anti-c-met tandem fc bispecific antibodies
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
CN107002119A (zh) 2014-03-24 2017-08-01 豪夫迈·罗氏有限公司 使用c‑met拮抗剂的癌症治疗及前者与hgf表达的关联
CN107001471B (zh) 2014-09-16 2022-01-18 西福根有限公司 抗met抗体和组合物
CN113150147A (zh) 2015-03-16 2021-07-23 塞尔德克斯医疗公司 抗-met抗体及其使用方法
GB201611123D0 (en) * 2016-06-27 2016-08-10 Euremab Srl Anti met antibodiesand uses thereof
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法
IT201800000535A1 (it) 2018-01-03 2019-07-03 Procedimenti per la cura del cancro.
KR102433184B1 (ko) * 2018-12-07 2022-08-17 서울대학교 산학협력단 항 c-Met 아고니스트 항체 및 이의 용도
KR102396194B1 (ko) * 2018-12-07 2022-05-10 서울대학교 산학협력단 항 c-Met 아고니스트 항체 및 이의 용도
CN114340684A (zh) 2019-09-16 2022-04-12 瑞泽恩制药公司 用于免疫pet成像的放射性标记的met结合蛋白

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651452B2 (en) * 1991-05-10 1994-07-21 Pharmacia & Upjohn S.P.A. Truncated forms of the hepatocyte growth factor receptor
US5686292A (en) * 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US6214344B1 (en) * 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
WO1998000543A1 (en) 1996-07-03 1998-01-08 Genentech, Inc. Hepatocyte growth factor receptor agonists and uses thereof

Also Published As

Publication number Publication date
WO2004108766A2 (en) 2004-12-16
EP1641828B1 (de) 2010-04-28
WO2004108766A3 (en) 2005-06-30
CA2524329A1 (en) 2004-12-16
ITMI20031127A1 (it) 2004-12-06
US7556804B2 (en) 2009-07-07
EP1641828A2 (de) 2006-04-05
ATE466031T1 (de) 2010-05-15
ITMI20031127A0 (it) 2003-06-05
DK1641828T3 (da) 2010-08-02
US20060140940A1 (en) 2006-06-29

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