DE602004022595D1 - GAG-bindende Proteine - Google Patents

GAG-bindende Proteine

Info

Publication number
DE602004022595D1
DE602004022595D1 DE602004022595T DE602004022595T DE602004022595D1 DE 602004022595 D1 DE602004022595 D1 DE 602004022595D1 DE 602004022595 T DE602004022595 T DE 602004022595T DE 602004022595 T DE602004022595 T DE 602004022595T DE 602004022595 D1 DE602004022595 D1 DE 602004022595D1
Authority
DE
Germany
Prior art keywords
gag
binding proteins
proteins
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004022595T
Other languages
English (en)
Inventor
Andreas J Kungl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protaffin Biotechnologie AG
Original Assignee
Protaffin Biotechnologie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protaffin Biotechnologie AG filed Critical Protaffin Biotechnologie AG
Publication of DE602004022595D1 publication Critical patent/DE602004022595D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5421—IL-8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE602004022595T 2003-12-04 2004-12-02 GAG-bindende Proteine Active DE602004022595D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0195203A AT412785B (de) 2003-12-04 2003-12-04 Gag-bindungsproteine

Publications (1)

Publication Number Publication Date
DE602004022595D1 true DE602004022595D1 (de) 2009-09-24

Family

ID=33494536

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004022595T Active DE602004022595D1 (de) 2003-12-04 2004-12-02 GAG-bindende Proteine

Country Status (20)

Country Link
US (4) US7585937B2 (de)
EP (5) EP2270038A3 (de)
JP (3) JP4980721B2 (de)
KR (2) KR101278459B1 (de)
CN (1) CN1890264B (de)
AT (3) AT412785B (de)
AU (1) AU2004295104B2 (de)
BR (1) BRPI0416544A (de)
CA (1) CA2546789A1 (de)
CY (2) CY1109480T1 (de)
DE (1) DE602004022595D1 (de)
DK (2) DK1689775T3 (de)
ES (2) ES2369139T3 (de)
IL (1) IL175565A0 (de)
NZ (1) NZ547612A (de)
PL (2) PL1689775T3 (de)
PT (2) PT1689775E (de)
SG (1) SG149000A1 (de)
SI (2) SI1752470T1 (de)
WO (1) WO2005054285A1 (de)

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* Cited by examiner, † Cited by third party
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AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
AU2006291990B2 (en) * 2005-09-13 2012-05-31 National Research Council Of Canada Methods and compositions for modulating tumor cell activity
CN100366637C (zh) * 2005-11-17 2008-02-06 中国人民解放军第四军医大学 人白细胞介素8拮抗蛋白及其制备方法
US9422356B2 (en) * 2006-01-31 2016-08-23 Republic Of Korea (Republic Of National Fisheries Research And Development Institute) Artificial signal peptide for expressing an insoluble protein as a soluble active form
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
CA2822302A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Methods of impairing osteoclast differentiation
EP1894571A1 (de) * 2006-08-29 2008-03-05 Protaffin Biotechnologie AG Verwendung von modifizierten IL-8 Proteinen zur Behandlung von Reperfusionsschäden und Transplantatabstossung
US20100075918A1 (en) * 2006-12-08 2010-03-25 Lokeshwar Vinata B Hyaluronidase inhibitors as anti-cancer agents
AT504685B1 (de) * 2006-12-20 2009-01-15 Protaffin Biotechnologie Ag Fusionsproteine
EP2157980A2 (de) * 2007-05-07 2010-03-03 Peptimmune, Inc. Verfahren zur ausgerichteten expansion von epitopen als antikörper-liganden
EP2042516A1 (de) * 2007-09-27 2009-04-01 Protaffin Biotechnologie AG Glycosaminoglycan-antagonisierende MCP-1-Mutanten und Verfahren zu seiner Verwendung
MX2010001307A (es) * 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
EP2053060A1 (de) 2007-10-24 2009-04-29 Protaffin Biotechnologie AG SDF-1-basierte Glycosamingolycan-Antagonisten und Verfahren zu ihrer Verwendung
WO2009099631A1 (en) * 2008-02-08 2009-08-13 Miles Lindsey A Novel plasminogen receptor, polypeptides & antibodies thereof
EA201101131A1 (ru) 2009-01-30 2012-01-30 Протаффин Биотехнологие Аг Новые мутанты мср-1, антагонизирующие гликозаминогликаны, и способы их применения
EA201200470A1 (ru) 2009-09-11 2012-08-30 Протаффин Биотехнологие Аг Композиция для лечения опосредуемого cxcl8 воспаления легкого
RU2627163C2 (ru) 2009-11-24 2017-08-03 Алетиа Байотерапьютикс Инк. Антикластериновые антитела и антигенсвязывающие фрагменты и их использование для уменьшения объема новообразований
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification
WO2012123585A1 (en) 2011-03-16 2012-09-20 Protaffin Biotechnologie Ag Fgfr1-based antagonists with improved glycosaminoglycan affinity and methods of using same
EP2729487A2 (de) 2011-07-08 2014-05-14 Protaffin Biotechnologie AG Neuartige sdf-1-basierter glycosaminoglycan-antagonist und verfahren zu ihrer verwendung
WO2013123588A1 (en) 2012-02-22 2013-08-29 Alethia Biotherapeutics Inc. Co-use of a clusterin inhibitor with an egfr inhibitor to treat cancer
CA2876517C (en) 2012-07-19 2019-01-08 Matthew Stuible Anti-siglec-15 antibodies
WO2014079957A1 (de) * 2012-11-23 2014-05-30 Bayer Cropscience Ag Selektive inhibition der ethylensignaltransduktion
WO2014109519A1 (ko) * 2013-01-10 2014-07-17 강원대학교산학협력단 작은안구증-연관 전사인자 유래의 펩타이드 및 이를 포함하는 조성물
US10047133B2 (en) 2014-01-22 2018-08-14 Antagonis Biotherapeutics Gmbh Glycosaminoglycan-antagonising fusion proteins and methods of using same
US20220281934A1 (en) 2019-08-29 2022-09-08 Antagonis Biotherapeutics Gmbh T-cell mobilizing cxcl10 mutant with increased glycosaminoglycan binding affinity
CN110791523B (zh) * 2019-12-13 2022-05-10 南京农业大学 一种棉花抗旱相关基因GhRCHY1及其应用

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US5234911A (en) * 1990-07-09 1993-08-10 Gist-Brocades, N.V. Substance with interleukin-8 inhibiting activity and process for its preparation
AU8947791A (en) 1990-11-01 1992-05-26 Scripps Research Institute, The Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions
DE59407415D1 (de) * 1993-01-08 1999-01-21 Hoechst Ag Verwendung von Leflunomid zur Hemmung von Interleukin 8
JP2694321B2 (ja) * 1993-03-10 1997-12-24 大塚製薬株式会社 インターロイキン−１阻害剤
US5527546A (en) * 1994-08-10 1996-06-18 Bayer Corporation Human interleukin 6 inhibitor
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US6852696B2 (en) * 1999-03-26 2005-02-08 The University Of Texas System Inhibitors of glycosaminoglycans
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EP1495050A1 (de) * 2002-04-10 2005-01-12 Applied Research Systems ARS Holding N.V. Neue mcp-protein-antagonisten
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine

Also Published As

Publication number Publication date
KR20070001917A (ko) 2007-01-04
CY1109480T1 (el) 2014-08-13
US20110144305A1 (en) 2011-06-16
ATE439376T1 (de) 2009-08-15
PL1689775T3 (pl) 2011-12-30
WO2005054285A1 (en) 2005-06-16
US7807413B2 (en) 2010-10-05
CN1890264A (zh) 2007-01-03
US20100331237A1 (en) 2010-12-30
ATA19522003A (de) 2004-12-15
BRPI0416544A (pt) 2007-01-09
ES2330362T3 (es) 2009-12-09
AU2004295104B2 (en) 2010-07-22
NZ547612A (en) 2009-07-31
US7585937B2 (en) 2009-09-08
JP2012139226A (ja) 2012-07-26
DK1689775T3 (da) 2011-09-26
EP2363411A1 (de) 2011-09-07
EP1752470B1 (de) 2009-08-12
CY1112330T1 (el) 2015-12-09
US20080112926A1 (en) 2008-05-15
CN1890264B (zh) 2014-01-22
US20090005541A1 (en) 2009-01-01
EP2311866A1 (de) 2011-04-20
KR101278459B1 (ko) 2013-07-01
EP1689775B1 (de) 2011-07-06
AU2004295104A1 (en) 2005-06-16
EP2270038A3 (de) 2011-02-23
EP1752470A1 (de) 2007-02-14
EP2270038A2 (de) 2011-01-05
KR20120063542A (ko) 2012-06-15
SI1689775T1 (sl) 2011-11-30
PT1752470E (pt) 2009-10-15
IL175565A0 (en) 2006-09-05
JP2007536906A (ja) 2007-12-20
SG149000A1 (en) 2009-01-29
JP4980721B2 (ja) 2012-07-18
DK1752470T3 (da) 2009-12-14
AT412785B (de) 2005-07-25
ATE515269T1 (de) 2011-07-15
ES2369139T3 (es) 2011-11-25
CA2546789A1 (en) 2005-06-16
PT1689775E (pt) 2011-10-13
JP2012165747A (ja) 2012-09-06
SI1752470T1 (sl) 2009-12-31
KR101188785B1 (ko) 2012-10-16
PL1752470T3 (pl) 2010-01-29
EP1689775A1 (de) 2006-08-16

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