DE602004012731D1 - Zubereitungen mit verzögerter freigabe enthaltend zink, und herstellung derselben - Google Patents
Zubereitungen mit verzögerter freigabe enthaltend zink, und herstellung derselbenInfo
- Publication number
- DE602004012731D1 DE602004012731D1 DE602004012731T DE602004012731T DE602004012731D1 DE 602004012731 D1 DE602004012731 D1 DE 602004012731D1 DE 602004012731 T DE602004012731 T DE 602004012731T DE 602004012731 T DE602004012731 T DE 602004012731T DE 602004012731 D1 DE602004012731 D1 DE 602004012731D1
- Authority
- DE
- Germany
- Prior art keywords
- zinc
- release composition
- containing sustained
- water
- sustained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title abstract 5
- 239000011701 zinc Substances 0.000 title abstract 5
- 229910052725 zinc Inorganic materials 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 238000013268 sustained release Methods 0.000 abstract 3
- 239000012730 sustained-release form Substances 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000002459 sustained effect Effects 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003751 zinc Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003126503 | 2003-05-01 | ||
| JP2003126503 | 2003-05-01 | ||
| PCT/JP2004/004791 WO2004096179A1 (en) | 2003-05-01 | 2004-04-01 | Zinc-containing sustained-release composition, its preparation, and method for producing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004012731D1 true DE602004012731D1 (de) | 2008-05-08 |
| DE602004012731T2 DE602004012731T2 (de) | 2009-04-09 |
Family
ID=33410296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004012731T Expired - Lifetime DE602004012731T2 (de) | 2003-05-01 | 2004-04-01 | Zubereitungen mit verzögerter freigabe enthaltend zink, und herstellung derselben |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7642230B2 (de) |
| EP (1) | EP1620072B1 (de) |
| JP (1) | JP4567668B2 (de) |
| CN (1) | CN100364499C (de) |
| AT (1) | ATE390126T1 (de) |
| DE (1) | DE602004012731T2 (de) |
| ES (1) | ES2300758T3 (de) |
| PL (1) | PL1620072T3 (de) |
| WO (1) | WO2004096179A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7534763B2 (en) | 2004-07-02 | 2009-05-19 | Bristol-Myers Squibb Company | Sustained release GLP-1 receptor modulators |
| WO2007139589A1 (en) * | 2006-05-26 | 2007-12-06 | Bristol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
| JP2009256241A (ja) * | 2008-04-16 | 2009-11-05 | Galenisearch Laboratories Inc | 生理活性蛋白質含有ナノ粒子組成物およびその製造方法 |
| EP2471554A1 (de) * | 2010-12-28 | 2012-07-04 | Hexal AG | Pharmazeutische Formulierung mit biopharmazeutischem Arzneimittel |
| CN110742065B (zh) * | 2019-10-25 | 2021-07-27 | 山东农业大学 | 一种纳米花负载农药制剂及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US15737A (en) * | 1856-09-16 | Mode of attaching- shafts to sleighs | ||
| ES2151541T3 (es) * | 1992-12-02 | 2001-01-01 | Alkermes Inc | Microesferas que contienen hormona del crecimiento de liberacion prolongada. |
| BR9509201A (pt) * | 1994-09-09 | 1997-12-30 | Takeda Chemical Industries Ltd | Preparação de liberação sustemtada uso de um sal de metal polivalente insolúvel em água ou ligeiramente solúvel em água e processo para produzir uma preparação de liberação sustentada |
| WO1997007788A2 (en) * | 1995-08-31 | 1997-03-06 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of an agent |
| ES2292189T3 (es) * | 1996-06-20 | 2008-03-01 | Novo Nordisk A/S | Preparaciones a base de insulina conteniendo manitol. |
| US6197350B1 (en) * | 1996-12-20 | 2001-03-06 | Takeda Chemical Industries, Ltd. | Method of producing a sustained-release preparation |
| US6663899B2 (en) * | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
| US6998137B2 (en) * | 2000-04-07 | 2006-02-14 | Macromed, Inc. | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
| JP2002348234A (ja) | 2001-05-28 | 2002-12-04 | Purotekku:Kk | 薬物封入無機物微粒子、その製造法及び薬物封入無機物微粒子製剤 |
| WO2003000282A1 (en) * | 2001-06-21 | 2003-01-03 | Genentech, Inc. | Sustained release formulation |
| JP2003081865A (ja) | 2001-09-12 | 2003-03-19 | Ltt Institute Co Ltd | 水不溶性徐放性組成物、その製剤及びその製造方法 |
-
2004
- 2004-04-01 AT AT04725163T patent/ATE390126T1/de not_active IP Right Cessation
- 2004-04-01 DE DE602004012731T patent/DE602004012731T2/de not_active Expired - Lifetime
- 2004-04-01 ES ES04725163T patent/ES2300758T3/es not_active Expired - Lifetime
- 2004-04-01 US US10/555,191 patent/US7642230B2/en not_active Expired - Fee Related
- 2004-04-01 PL PL04725163T patent/PL1620072T3/pl unknown
- 2004-04-01 JP JP2006507705A patent/JP4567668B2/ja not_active Expired - Fee Related
- 2004-04-01 CN CNB2004800117999A patent/CN100364499C/zh not_active Expired - Fee Related
- 2004-04-01 EP EP04725163A patent/EP1620072B1/de not_active Expired - Lifetime
- 2004-04-01 WO PCT/JP2004/004791 patent/WO2004096179A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004096179A1 (en) | 2004-11-11 |
| CN1780607A (zh) | 2006-05-31 |
| ES2300758T3 (es) | 2008-06-16 |
| JP4567668B2 (ja) | 2010-10-20 |
| CN100364499C (zh) | 2008-01-30 |
| JP2006525319A (ja) | 2006-11-09 |
| PL1620072T3 (pl) | 2008-10-31 |
| EP1620072A1 (de) | 2006-02-01 |
| EP1620072B1 (de) | 2008-03-26 |
| US20060210629A1 (en) | 2006-09-21 |
| US7642230B2 (en) | 2010-01-05 |
| ATE390126T1 (de) | 2008-04-15 |
| DE602004012731T2 (de) | 2009-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |