DE602004012273D1 - Bestimmung der sequenz eines polynukleotids - Google Patents

Bestimmung der sequenz eines polynukleotids

Info

Publication number
DE602004012273D1
DE602004012273D1 DE602004012273T DE602004012273T DE602004012273D1 DE 602004012273 D1 DE602004012273 D1 DE 602004012273D1 DE 602004012273 T DE602004012273 T DE 602004012273T DE 602004012273 T DE602004012273 T DE 602004012273T DE 602004012273 D1 DE602004012273 D1 DE 602004012273D1
Authority
DE
Germany
Prior art keywords
target polynucleotide
sequence
polymerase
polynucleotide
determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004012273T
Other languages
English (en)
Other versions
DE602004012273T2 (de
Inventor
Daniel Henry Densham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Publication of DE602004012273D1 publication Critical patent/DE602004012273D1/de
Application granted granted Critical
Publication of DE602004012273T2 publication Critical patent/DE602004012273T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
    • C12Q2521/101—DNA polymerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/113—Time
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/501—Detection characterised by immobilisation to a surface being an array of oligonucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE602004012273T 2003-07-24 2004-07-26 Bestimmung der sequenz eines polynukleotids Expired - Lifetime DE602004012273T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0317343 2003-07-24
GBGB0317343.2A GB0317343D0 (en) 2003-07-24 2003-07-24 Polynucleotide sequencing
PCT/GB2004/003232 WO2005010210A2 (en) 2003-07-24 2004-07-26 Determining the sequence of a polynucleotide

Publications (2)

Publication Number Publication Date
DE602004012273D1 true DE602004012273D1 (de) 2008-04-17
DE602004012273T2 DE602004012273T2 (de) 2009-04-30

Family

ID=27772590

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004012273T Expired - Lifetime DE602004012273T2 (de) 2003-07-24 2004-07-26 Bestimmung der sequenz eines polynukleotids

Country Status (21)

Country Link
US (3) US7604963B2 (de)
EP (1) EP1649051B1 (de)
JP (1) JP4394684B2 (de)
KR (1) KR20060052863A (de)
CN (1) CN1852991A (de)
AT (1) ATE388243T1 (de)
AU (1) AU2004259893A1 (de)
BR (1) BRPI0412813A (de)
CA (2) CA2780958C (de)
DE (1) DE602004012273T2 (de)
DK (1) DK1649051T3 (de)
ES (1) ES2303083T3 (de)
GB (1) GB0317343D0 (de)
IL (1) IL173314A0 (de)
IS (1) IS8314A (de)
MX (1) MXPA06000962A (de)
PL (1) PL1649051T3 (de)
PT (1) PT1649051E (de)
RU (1) RU2006105626A (de)
SI (1) SI1649051T1 (de)
WO (1) WO2005010210A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1017848T3 (da) * 1997-07-28 2003-02-10 Medical Biosystems Ltd Nucleinsyresekvensanalyse
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
JP2004347621A (ja) * 2003-04-24 2004-12-09 Dainippon Printing Co Ltd 透過型スクリーン
JP4431549B2 (ja) * 2006-05-31 2010-03-17 株式会社日立ハイテクノロジーズ 蛍光分析装置
GB0721340D0 (en) * 2007-10-30 2007-12-12 Isis Innovation Polymerase-based single-molecule DNA sequencing
JP4982523B2 (ja) * 2009-05-11 2012-07-25 株式会社日立ハイテクノロジーズ 蛍光分析方法，蛍光分析装置及び画像検出方法
WO2011159942A1 (en) 2010-06-18 2011-12-22 Illumina, Inc. Conformational probes and methods for sequencing nucleic acids
US9279154B2 (en) * 2011-12-21 2016-03-08 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
US9593371B2 (en) * 2013-12-27 2017-03-14 Intel Corporation Integrated photonic electronic sensor arrays for nucleic acid sequencing
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
US11225687B2 (en) 2016-04-04 2022-01-18 The Trustees Of Columbia University In The City Of New York DNA sequencing by synthesis with nucleotide analogues and Raman detection
CA3021769C (en) 2016-04-29 2021-11-23 Omniome, Inc. Sequencing method employing ternary complex destabilization to identify cognate nucleotides
US10428378B2 (en) 2016-08-15 2019-10-01 Omniome, Inc. Sequencing method for rapid identification and processing of cognate nucleotide pairs
JP6828140B2 (ja) 2016-08-15 2021-02-10 オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． 核酸をシーケンシングするための方法及びシステム
EP3562962B1 (de) 2016-12-30 2022-01-05 Omniome, Inc. Verfahren und system unter verwendung von unterscheidbaren polymerasen zum nachweis von ternären komplexen und zur identifizierung von verwandten nukleotiden
CN110249059B (zh) 2017-01-20 2021-04-13 欧姆尼欧美公司 核酸的等位基因特异性捕获
US10975427B2 (en) 2017-01-20 2021-04-13 Omniome, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
US9932631B1 (en) 2017-09-11 2018-04-03 Omniome, Inc. Genotyping by polymerase binding
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
EP3697932A1 (de) 2017-10-19 2020-08-26 Omniome, Inc. Gleichzeitige hintergrundreduktion und komplexstabilisierung in bindungsassayarbeitsflüssen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6379895B1 (en) * 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
AU726501B2 (en) * 1996-06-04 2000-11-09 University Of Utah Research Foundation Monitoring hybridization during PCR
DK1017848T3 (da) * 1997-07-28 2003-02-10 Medical Biosystems Ltd Nucleinsyresekvensanalyse
CN1245218A (zh) 1998-08-19 2000-02-23 中国人民解放军军事医学科学院放射医学研究所 一种固相逐个碱基核酸分析方法和仪器
US7270951B1 (en) * 1999-03-10 2007-09-18 Asm Scientific, Inc. Method for direct nucleic acid sequencing
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
WO2001016375A2 (en) 1999-08-30 2001-03-08 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
US6908736B1 (en) * 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
GB0112238D0 (en) 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6982165B2 (en) * 2001-09-24 2006-01-03 Intel Corporation Nucleic acid sequencing by raman monitoring of molecular deconstruction
GB0413082D0 (en) * 2004-06-11 2004-07-14 Medical Biosystems Ltd Method

Also Published As

Publication number Publication date
IL173314A0 (en) 2006-06-11
GB0317343D0 (en) 2003-08-27
WO2005010210A2 (en) 2005-02-03
CN1852991A (zh) 2006-10-25
PL1649051T3 (pl) 2008-12-31
EP1649051A2 (de) 2006-04-26
IS8314A (is) 2006-02-20
DE602004012273T2 (de) 2009-04-30
JP4394684B2 (ja) 2010-01-06
AU2004259893A1 (en) 2005-02-03
SI1649051T1 (sl) 2008-10-31
US7888073B2 (en) 2011-02-15
ATE388243T1 (de) 2008-03-15
CA2533579A1 (en) 2005-02-03
EP1649051B1 (de) 2008-03-05
DK1649051T3 (da) 2008-07-07
ES2303083T3 (es) 2008-08-01
KR20060052863A (ko) 2006-05-19
CA2780958A1 (en) 2005-02-03
WO2005010210A3 (en) 2005-03-24
CA2780958C (en) 2016-10-25
JP2006528485A (ja) 2006-12-21
US20080070236A1 (en) 2008-03-20
US7604963B2 (en) 2009-10-20
US8592183B2 (en) 2013-11-26
US20100279288A1 (en) 2010-11-04
RU2006105626A (ru) 2006-08-10
BRPI0412813A (pt) 2006-09-26
MXPA06000962A (es) 2006-03-30
US20110097729A1 (en) 2011-04-28
PT1649051E (pt) 2008-05-26
CA2533579C (en) 2012-09-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GEN-PROBE INCORPORATED, SAN DIEGO, CALIF., US