DE602004010578T8 - Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien - Google Patents

Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien Download PDF

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Publication number
DE602004010578T8
DE602004010578T8 DE602004010578T DE602004010578T DE602004010578T8 DE 602004010578 T8 DE602004010578 T8 DE 602004010578T8 DE 602004010578 T DE602004010578 T DE 602004010578T DE 602004010578 T DE602004010578 T DE 602004010578T DE 602004010578 T8 DE602004010578 T8 DE 602004010578T8
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Germany
Prior art keywords
animal cell
cell colonies
housing animal
housing
colonies
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DE602004010578T
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DE602004010578T3 (de
DE602004010578D1 (de
DE602004010578T2 (de
Inventor
Stephen Richmond
Christopher Mann
Andrew Board
Yonggang Jiang
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Molecular Devices New Milton Ltd
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Genetix Ltd
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Application filed by Genetix Ltd filed Critical Genetix Ltd
Publication of DE602004010578D1 publication Critical patent/DE602004010578D1/de
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Publication of DE602004010578T2 publication Critical patent/DE602004010578T2/de
Publication of DE602004010578T8 publication Critical patent/DE602004010578T8/de
Publication of DE602004010578T3 publication Critical patent/DE602004010578T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C12M33/06Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles for multiple inoculation or multiple collection of samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0832Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838Capillaries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N2015/1472Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497Particle shape

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Computer Hardware Design (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602004010578.3T 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien Expired - Lifetime DE602004010578T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US631845 2003-08-01
US10/631,845 US7776584B2 (en) 2003-08-01 2003-08-01 Animal cell colony picking apparatus and method
EP04254370.2A EP1502649B2 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien

Publications (4)

Publication Number Publication Date
DE602004010578D1 DE602004010578D1 (de) 2008-01-24
DE602004010578T2 DE602004010578T2 (de) 2008-05-21
DE602004010578T8 true DE602004010578T8 (de) 2008-08-28
DE602004010578T3 DE602004010578T3 (de) 2017-08-31

Family

ID=33541530

Family Applications (6)

Application Number Title Priority Date Filing Date
DE06005877T Pending DE06005877T1 (de) 2003-08-01 2004-07-22 Verfahren zum Auswählen und Aufnehmen von Tierzellenkolonien
DE202004021397U Ceased DE202004021397U1 (de) 2003-08-01 2004-07-22 Vorrichtung zur Aufnahme von Tierzellenkolonien
DE602004010578.3T Expired - Lifetime DE602004010578T3 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien
DE07020151T Pending DE07020151T1 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien
DE602004027761T Expired - Lifetime DE602004027761D1 (de) 2003-08-01 2004-07-22 Verfahren zum Auswählen und Aufnehmen von Tierzellenkolonien
DE04254370T Pending DE04254370T1 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE06005877T Pending DE06005877T1 (de) 2003-08-01 2004-07-22 Verfahren zum Auswählen und Aufnehmen von Tierzellenkolonien
DE202004021397U Ceased DE202004021397U1 (de) 2003-08-01 2004-07-22 Vorrichtung zur Aufnahme von Tierzellenkolonien

Family Applications After (3)

Application Number Title Priority Date Filing Date
DE07020151T Pending DE07020151T1 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien
DE602004027761T Expired - Lifetime DE602004027761D1 (de) 2003-08-01 2004-07-22 Verfahren zum Auswählen und Aufnehmen von Tierzellenkolonien
DE04254370T Pending DE04254370T1 (de) 2003-08-01 2004-07-22 Vorrichtung und Verfahren zur Aufnahme von Tierzellenkolonien

Country Status (3)

Country Link
US (7) US7776584B2 (de)
EP (3) EP1502649B2 (de)
DE (6) DE06005877T1 (de)

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DE04254370T1 (de) 2007-04-19
EP1754537A1 (de) 2007-02-21
US8293526B2 (en) 2012-10-23
US20050026221A1 (en) 2005-02-03
US20090116714A1 (en) 2009-05-07
EP1502649B2 (de) 2017-04-05
US8034625B2 (en) 2011-10-11
US7776584B2 (en) 2010-08-17
EP1882523B1 (de) 2018-05-02
DE602004010578T3 (de) 2017-08-31
DE602004010578D1 (de) 2008-01-24
DE602004010578T2 (de) 2008-05-21
US8034612B2 (en) 2011-10-11
US8293527B2 (en) 2012-10-23
DE602004027761D1 (de) 2010-07-29
DE07020151T1 (de) 2008-11-06
DE202004021397U1 (de) 2007-11-29
EP1754537B1 (de) 2010-06-16
US20120028238A1 (en) 2012-02-02
US20120028237A1 (en) 2012-02-02
EP1882523A3 (de) 2008-07-16
US20060177878A1 (en) 2006-08-10
DE06005877T1 (de) 2007-08-02
US8293520B2 (en) 2012-10-23
EP1502649A1 (de) 2005-02-02
US20120028239A1 (en) 2012-02-02
EP1502649B1 (de) 2007-12-12
US8293525B2 (en) 2012-10-23
EP1882523A2 (de) 2008-01-30
US20120028240A1 (en) 2012-02-02

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