DE60139618D1 - Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien - Google Patents

Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien

Info

Publication number
DE60139618D1
DE60139618D1 DE60139618T DE60139618T DE60139618D1 DE 60139618 D1 DE60139618 D1 DE 60139618D1 DE 60139618 T DE60139618 T DE 60139618T DE 60139618 T DE60139618 T DE 60139618T DE 60139618 D1 DE60139618 D1 DE 60139618D1
Authority
DE
Germany
Prior art keywords
platelet
blood coagulation
inhibition
gpiib
iiia receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60139618T
Other languages
English (en)
Inventor
Eli Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Haemoscope Corp
Original Assignee
Haemoscope Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haemoscope Corp filed Critical Haemoscope Corp
Application granted granted Critical
Publication of DE60139618D1 publication Critical patent/DE60139618D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162—Oscillations being torsional, e.g. produced by rotating bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162—Oscillations being torsional, e.g. produced by rotating bodies
    • G01N11/167—Sample holder oscillates, e.g. rotating crucible

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
DE60139618T 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien Expired - Lifetime DE60139618D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/591,371 US6613573B1 (en) 1999-02-22 2000-06-09 Method and apparatus for monitoring anti-platelet agents
PCT/US2001/018154 WO2001096879A2 (en) 2000-06-09 2001-06-05 Method and apparatus for monitoring anti-platelet agents

Publications (1)

Publication Number Publication Date
DE60139618D1 true DE60139618D1 (de) 2009-10-01

Family

ID=24366228

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1287349T Pending DE1287349T1 (de) 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien
DE60139618T Expired - Lifetime DE60139618D1 (de) 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1287349T Pending DE1287349T1 (de) 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien

Country Status (8)

Country Link
US (1) US6613573B1 (de)
EP (1) EP1287349B1 (de)
JP (2) JP3792198B2 (de)
CN (2) CN102183665B (de)
AT (1) ATE440279T1 (de)
AU (2) AU7524901A (de)
DE (2) DE1287349T1 (de)
WO (1) WO2001096879A2 (de)

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US8076144B2 (en) * 1999-02-22 2011-12-13 Cora Healthcare, Inc. Protocol for risk stratification of ischemic events and optimized individualized treatment
US7179652B2 (en) * 1999-02-22 2007-02-20 Haemoscope Corporation Protocol for monitoring platelet inhibition
US6613573B1 (en) * 1999-02-22 2003-09-02 Haemoscope Corporation Method and apparatus for monitoring anti-platelet agents
US7732213B2 (en) * 1999-02-22 2010-06-08 Coramed Healthcare, Inc. Method of evaluating patient hemostasis
US8008086B2 (en) * 1999-02-22 2011-08-30 Cora Healthcare, Inc. Protocol for monitoring direct thrombin inhibition
US6787363B2 (en) * 1999-02-22 2004-09-07 Haemoscope Corporation Method and apparatus for hemostasis and blood management
US6797519B2 (en) * 2001-10-10 2004-09-28 Haemoscope Corporation Method and apparatus for diagnosing hemostasis
JP2005538383A (ja) 2002-09-10 2005-12-15 プラコア・インコーポレーテッド 血小板機能を監視する方法および装置
US7335335B2 (en) * 2003-08-01 2008-02-26 Enrique Saldivar Apparatus and method to measure platelet contractility
US6890299B2 (en) 2003-04-08 2005-05-10 Haemoscope Corporation Method and apparatus for monitoring hemostasis in connection with artificial surface devices
US7261861B2 (en) * 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
US7524670B2 (en) * 2003-08-05 2009-04-28 Haemoscope Corporation Protocol and apparatus for determining heparin-induced thrombocytopenia
US7892188B2 (en) * 2003-10-22 2011-02-22 Hemosonics, Llc Method and apparatus for characterization of clot formation
DE102005005824A1 (de) * 2005-02-08 2006-08-17 Zlb Behring Gmbh Methode zur Differenzierung von Faktor XIII-gegenüber Fibrinogen-Mangelzuständen unter Einsatz thrombelastographischer Techniken
EP1875232A2 (de) * 2005-04-25 2008-01-09 PlaCor, Inc. Verfahren und vorrichtungen zur überwachung der blutplättchenfunktion
JP4267592B2 (ja) * 2005-05-23 2009-05-27 潤 川崎 抗血栓薬薬効試験法
US7879615B2 (en) 2005-10-20 2011-02-01 Coramed Technologies, Llc Hemostasis analyzer and method
AU2006331583A1 (en) * 2005-12-22 2007-07-05 Schering Corporation Thrombin receptor antagonists as prophylaxis to complications from cardiopulmonary surgery
US7949498B2 (en) * 2006-10-02 2011-05-24 University Of Virginia Patent Foundation Method, system and computer program product for registration of multi-dimensional datasets
US20100099130A1 (en) * 2006-10-25 2010-04-22 Placor Inc. Methods and devices for monitoring platelet function
US20080114549A1 (en) * 2006-11-09 2008-05-15 Mark Evan Schafer Rapid response blood analyzer
WO2008062520A1 (fr) * 2006-11-22 2008-05-29 Jun Kawasaki Procédé d'expérimentation efficace de médicaments pour un agent antitrombotique
WO2009075891A2 (en) * 2007-12-12 2009-06-18 Kmg2 Sensors Corporation (Kmg2) Magnetoelastic sensor element having a liquid-solid interface with a roughened nano/microstructure
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
DK2555704T3 (da) 2010-04-08 2019-08-05 Hemosonics Llc Visning af hæmostatiske parametre
ES2854873T3 (es) 2011-02-15 2021-09-23 Hemosonics Llc Dispositivos, sistemas y procedimientos para la evaluación de la hemostasia
EP2676143B1 (de) 2011-02-15 2023-11-01 Hemosonics, Llc Charakterisierung von hämostase- und sauerstofftransportparametern
US9626650B2 (en) 2011-04-14 2017-04-18 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10445846B2 (en) 2011-04-14 2019-10-15 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US20120294767A1 (en) 2011-05-19 2012-11-22 Hemosonics Llc Portable hemostasis analyzer
US20130046153A1 (en) 2011-08-16 2013-02-21 Elwha LLC, a limited liability company of the State of Delaware Systematic distillation of status data relating to regimen compliance
CN103305591B (zh) * 2012-03-06 2014-07-30 辽宁诺康生物制药有限责任公司 一种类凝血酶效价测定方法
ES2706995T3 (es) * 2012-12-18 2019-04-02 Daiichi Sankyo Co Ltd Procedimiento para medir la generación de trombina
US8921115B2 (en) 2013-03-07 2014-12-30 Medtronic, Inc. Apparatus and method for analyzing blood clotting
DE202014002289U1 (de) 2013-03-15 2014-09-24 Coramed Technologies, Llc Vorrichtung und Kartusche zur Bestimmung der Blutgerinnung
CN105164528B (zh) 2013-03-15 2019-04-26 科拉梅德科技有限公司 用于止血测试的设备、筒和方法
US10379128B2 (en) 2013-04-23 2019-08-13 Medtronic, Inc. Apparatus and method for analyzing blood clotting
CN103398922B (zh) * 2013-07-09 2015-09-30 广东石油化工学院 一种血栓弹力测量装置及其测量方法
US10823743B1 (en) 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
CN104614539A (zh) * 2013-11-05 2015-05-13 北京乐普医疗科技有限责任公司 一种血栓弹力图仪
CN106574922B (zh) * 2014-05-05 2020-06-05 美国血液技术公司 用于检测纤维蛋白溶解和纤溶亢进的方法学和试剂
EP3175245B1 (de) 2014-07-31 2019-05-29 Haemonetics Corporation Detektion und klassifizierung von antikoagulans unter verwendung eines gerinnungstests
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
CN105467108A (zh) * 2015-12-19 2016-04-06 开滦总医院 溶栓药物个体化应用剂量的体外测定试验方法
CN115561306A (zh) 2017-04-20 2023-01-03 海默索尼克斯有限公司 用于止血功能分析的一次性系统
WO2020051761A1 (zh) * 2018-09-11 2020-03-19 深圳迈瑞生物医疗电子股份有限公司 凝血分析仪及其检测样本的方法、存储介质
JP7230429B2 (ja) 2018-10-25 2023-03-01 ソニーグループ株式会社 血小板凝集能解析装置、血小板凝集能解析方法及び血小板凝集能解析システム
CN112881235B (zh) * 2019-11-29 2021-11-16 深圳市帝迈生物技术有限公司 一种样本分析装置和计算凝固时长的方法
CN111579398B (zh) * 2020-05-28 2023-04-07 常熟常江生物技术有限公司 一种体外血栓物性检测装置

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US5223227A (en) 1989-06-19 1993-06-29 Haemoscope Corporation Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
US5854423A (en) 1996-03-20 1998-12-29 Venegas; Jose G. Apparatus and method for assessment of visco-elasticity and shear adherence strength properties of blood clots
DE19781870T1 (de) * 1996-04-30 2000-02-24 Medtronic Inc Verfahren zur Bestimmung der Blutplättcheninhibitor-Ansprechempfindlichkeit
AU4101697A (en) * 1996-11-22 1998-05-28 Robert A. Levine Process for enhancing the aggregation and/or agglutination of erythrocytes prior to centrifugation
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AUPP660798A0 (en) * 1998-10-20 1998-11-12 Monash University Method for measuring cellular adhesion
US6225126B1 (en) * 1999-02-22 2001-05-01 Haemoscope Corporation Method and apparatus for measuring hemostasis
US6613573B1 (en) * 1999-02-22 2003-09-02 Haemoscope Corporation Method and apparatus for monitoring anti-platelet agents

Also Published As

Publication number Publication date
CN102183665A (zh) 2011-09-14
AU2001275249B2 (en) 2005-10-27
JP3792198B2 (ja) 2006-07-05
EP1287349A2 (de) 2003-03-05
JP2006145548A (ja) 2006-06-08
WO2001096879A2 (en) 2001-12-20
ATE440279T1 (de) 2009-09-15
DE1287349T1 (de) 2003-09-18
EP1287349B1 (de) 2009-08-19
CN1436304A (zh) 2003-08-13
CN102183665B (zh) 2013-08-21
JP4086203B2 (ja) 2008-05-14
JP2004503781A (ja) 2004-02-05
US6613573B1 (en) 2003-09-02
WO2001096879A3 (en) 2002-06-13
AU7524901A (en) 2001-12-24

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