ATE440279T1 - Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien - Google Patents

Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien

Info

Publication number
ATE440279T1
ATE440279T1 AT01941938T AT01941938T ATE440279T1 AT E440279 T1 ATE440279 T1 AT E440279T1 AT 01941938 T AT01941938 T AT 01941938T AT 01941938 T AT01941938 T AT 01941938T AT E440279 T1 ATE440279 T1 AT E440279T1
Authority
AT
Austria
Prior art keywords
platelet
blood coagulation
inhibition
gpiib
agents
Prior art date
Application number
AT01941938T
Other languages
English (en)
Inventor
Eli Cohen
Original Assignee
Cora Healthcare Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cora Healthcare Inc filed Critical Cora Healthcare Inc
Application granted granted Critical
Publication of ATE440279T1 publication Critical patent/ATE440279T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162Oscillations being torsional, e.g. produced by rotating bodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162Oscillations being torsional, e.g. produced by rotating bodies
    • G01N11/167Sample holder oscillates, e.g. rotating crucible

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01941938T 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien ATE440279T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/591,371 US6613573B1 (en) 1999-02-22 2000-06-09 Method and apparatus for monitoring anti-platelet agents
PCT/US2001/018154 WO2001096879A2 (en) 2000-06-09 2001-06-05 Method and apparatus for monitoring anti-platelet agents

Publications (1)

Publication Number Publication Date
ATE440279T1 true ATE440279T1 (de) 2009-09-15

Family

ID=24366228

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01941938T ATE440279T1 (de) 2000-06-09 2001-06-05 Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien

Country Status (8)

Country Link
US (1) US6613573B1 (de)
EP (1) EP1287349B1 (de)
JP (2) JP3792198B2 (de)
CN (2) CN102183665B (de)
AT (1) ATE440279T1 (de)
AU (2) AU7524901A (de)
DE (2) DE60139618D1 (de)
WO (1) WO2001096879A2 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8008086B2 (en) * 1999-02-22 2011-08-30 Cora Healthcare, Inc. Protocol for monitoring direct thrombin inhibition
US7179652B2 (en) * 1999-02-22 2007-02-20 Haemoscope Corporation Protocol for monitoring platelet inhibition
US6787363B2 (en) * 1999-02-22 2004-09-07 Haemoscope Corporation Method and apparatus for hemostasis and blood management
US6797519B2 (en) * 2001-10-10 2004-09-28 Haemoscope Corporation Method and apparatus for diagnosing hemostasis
US6613573B1 (en) * 1999-02-22 2003-09-02 Haemoscope Corporation Method and apparatus for monitoring anti-platelet agents
US7732213B2 (en) * 1999-02-22 2010-06-08 Coramed Healthcare, Inc. Method of evaluating patient hemostasis
US8076144B2 (en) * 1999-02-22 2011-12-13 Cora Healthcare, Inc. Protocol for risk stratification of ischemic events and optimized individualized treatment
WO2004024026A2 (en) * 2002-09-10 2004-03-25 Ericson Daniel G Method and device for monitoring platelet function
US7335335B2 (en) * 2003-08-01 2008-02-26 Enrique Saldivar Apparatus and method to measure platelet contractility
US6890299B2 (en) 2003-04-08 2005-05-10 Haemoscope Corporation Method and apparatus for monitoring hemostasis in connection with artificial surface devices
US7261861B2 (en) * 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
US7524670B2 (en) * 2003-08-05 2009-04-28 Haemoscope Corporation Protocol and apparatus for determining heparin-induced thrombocytopenia
US7892188B2 (en) * 2003-10-22 2011-02-22 Hemosonics, Llc Method and apparatus for characterization of clot formation
DE102005005824A1 (de) * 2005-02-08 2006-08-17 Zlb Behring Gmbh Methode zur Differenzierung von Faktor XIII-gegenüber Fibrinogen-Mangelzuständen unter Einsatz thrombelastographischer Techniken
US20060269978A1 (en) * 2005-04-25 2006-11-30 Haworth William S Method and device for monitoring platelet function
JP4267592B2 (ja) * 2005-05-23 2009-05-27 潤 川崎 抗血栓薬薬効試験法
US7879615B2 (en) 2005-10-20 2011-02-01 Coramed Technologies, Llc Hemostasis analyzer and method
EP1971336A2 (de) * 2005-12-22 2008-09-24 Shering Corporation Thrombin-rezeptor-antagonisten zur prophylaxe vor komplikationen einer kardiopulmonalen operation
US7949498B2 (en) * 2006-10-02 2011-05-24 University Of Virginia Patent Foundation Method, system and computer program product for registration of multi-dimensional datasets
WO2008070324A2 (en) * 2006-10-25 2008-06-12 Placor, Inc. Methods and devices for monitoring platelet function
US20080114549A1 (en) * 2006-11-09 2008-05-15 Mark Evan Schafer Rapid response blood analyzer
WO2008062520A1 (fr) * 2006-11-22 2008-05-29 Jun Kawasaki Procédé d'expérimentation efficace de médicaments pour un agent antitrombotique
WO2009075891A2 (en) * 2007-12-12 2009-06-18 Kmg2 Sensors Corporation (Kmg2) Magnetoelastic sensor element having a liquid-solid interface with a roughened nano/microstructure
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
EP2555704B1 (de) 2010-04-08 2019-05-29 Hemosonics, Llc Anzeige von blutstillungsparametern
AU2012364909B2 (en) 2011-02-15 2016-11-24 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
PT2676136T (pt) 2011-02-15 2021-03-25 Hemosonics Llc Dispositivos, sistemas e métodos para avaliação de hemostasia
US10853819B2 (en) 2011-04-14 2020-12-01 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10445846B2 (en) 2011-04-14 2019-10-15 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
WO2012159021A2 (en) 2011-05-19 2012-11-22 Hemosonics, Llc Portable hemostasis analyzer
US8816814B2 (en) 2011-08-16 2014-08-26 Elwha Llc Systematic distillation of status data responsive to whether or not a wireless signal has been received and relating to regimen compliance
CN103305591B (zh) * 2012-03-06 2014-07-30 辽宁诺康生物制药有限责任公司 一种类凝血酶效价测定方法
EP2937695B1 (de) * 2012-12-18 2018-10-24 Daiichi Sankyo Company, Limited Verfahren zur messung der thrombinerzeugung
US8921115B2 (en) 2013-03-07 2014-12-30 Medtronic, Inc. Apparatus and method for analyzing blood clotting
DE202014002289U1 (de) 2013-03-15 2014-09-24 Coramed Technologies, Llc Vorrichtung und Kartusche zur Bestimmung der Blutgerinnung
WO2014144259A1 (en) 2013-03-15 2014-09-18 Coramed Technologies, Llc Apparatus, cartridge and method for hemostasis testing
US10379128B2 (en) 2013-04-23 2019-08-13 Medtronic, Inc. Apparatus and method for analyzing blood clotting
CN103398922B (zh) * 2013-07-09 2015-09-30 广东石油化工学院 一种血栓弹力测量装置及其测量方法
US10823743B1 (en) * 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
CN104614539A (zh) * 2013-11-05 2015-05-13 北京乐普医疗科技有限责任公司 一种血栓弹力图仪
US9354243B2 (en) * 2014-05-05 2016-05-31 Haemonetics Corporation Methodologies and reagents for detecting fibrinolysis and hyperfibrinolysis in a blood sample using viscoelastic analysis
ES2907190T3 (es) 2014-07-31 2022-04-22 Haemonetics Corp Detección de la reversión de un anticoagulante mediante pruebas de coagulación por ecarina y factor Xa
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
CN105467108A (zh) * 2015-12-19 2016-04-06 开滦总医院 溶栓药物个体化应用剂量的体外测定试验方法
WO2018195468A2 (en) 2017-04-20 2018-10-25 Hemosonics, Llc Disposable system for analysis of hemostatic function
EP3851857A4 (de) * 2018-09-11 2021-09-29 Shenzhen Mindray Bio-Medical Electronics Co., Ltd Blutgerinnungsanalysator, probendetektionsverfahren dafür und speichermedium
JP7230429B2 (ja) * 2018-10-25 2023-03-01 ソニーグループ株式会社 血小板凝集能解析装置、血小板凝集能解析方法及び血小板凝集能解析システム
CN112881235B (zh) * 2019-11-29 2021-11-16 深圳市帝迈生物技术有限公司 一种样本分析装置和计算凝固时长的方法
CN111579398B (zh) * 2020-05-28 2023-04-07 常熟常江生物技术有限公司 一种体外血栓物性检测装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018788A1 (en) * 1989-06-19 1990-12-19 Leon Zuckerman Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
US5223227A (en) 1989-06-19 1993-06-29 Haemoscope Corporation Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
US5854423A (en) 1996-03-20 1998-12-29 Venegas; Jose G. Apparatus and method for assessment of visco-elasticity and shear adherence strength properties of blood clots
DE29723808U1 (de) * 1996-04-30 1999-11-04 Medtronic Inc Vorrichtung zur Bestimmung der Blutplättcheninhibitor-Ansprechempfindlichkeit
AU4101697A (en) * 1996-11-22 1998-05-28 Robert A. Levine Process for enhancing the aggregation and/or agglutination of erythrocytes prior to centrifugation
US6010911A (en) 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
AUPP660798A0 (en) * 1998-10-20 1998-11-12 Monash University Method for measuring cellular adhesion
US6613573B1 (en) * 1999-02-22 2003-09-02 Haemoscope Corporation Method and apparatus for monitoring anti-platelet agents
US6225126B1 (en) * 1999-02-22 2001-05-01 Haemoscope Corporation Method and apparatus for measuring hemostasis

Also Published As

Publication number Publication date
JP3792198B2 (ja) 2006-07-05
CN102183665B (zh) 2013-08-21
US6613573B1 (en) 2003-09-02
WO2001096879A2 (en) 2001-12-20
EP1287349A2 (de) 2003-03-05
JP4086203B2 (ja) 2008-05-14
WO2001096879A3 (en) 2002-06-13
AU2001275249B2 (en) 2005-10-27
DE60139618D1 (de) 2009-10-01
AU7524901A (en) 2001-12-24
DE1287349T1 (de) 2003-09-18
CN1436304A (zh) 2003-08-13
EP1287349B1 (de) 2009-08-19
CN102183665A (zh) 2011-09-14
JP2004503781A (ja) 2004-02-05
JP2006145548A (ja) 2006-06-08

Similar Documents

Publication Publication Date Title
ATE440279T1 (de) Verfahren und vorrichtung zur überwachung von antiblutplättchenagenzien
CY1116890T1 (el) Πρωτοκολλο για παρακολουθηση αναστολης αιμοπεταλιου
DE60309030D1 (de) Vorrichtung zum schliessen von gefässwunden
DE60130770D1 (de) Vorrichtung zum verschliessen von vaskularen punktionen
DE69908602D1 (de) Verfahren und vorrichtung zum vorhersagen von physiologischen messwerten
DE602004026731D1 (de) Protokoll zur bestimmung von heparininduzierter thrombozytopenie
Varadi et al. Thrombin generation assay and other universal tests for monitoring haemophilia therapy
ATE313805T1 (de) Verfahren und vorrichtung zur beurteilung eines flüssigkeitsdosierungsvorgangs
JP2004503781A5 (de)
ATE322860T1 (de) Verminderung von alarmmissständen in einem physiologischen überwachungsgerät
ATE434182T1 (de) Vorrichtung und verfahren zur erfassung von gerinnungsfunktionen der globalen, insbesondere der primären hämostase
ATE282208T1 (de) Verfahren und vorrichtung zum vorhersagen von haemostatischer funktionsstörung in patientenproben
Madsen et al. Tissue factor activates allosteric networks in factor VIIa through structural and dynamic changes
WO2002034110A3 (en) Method of determining global coagulability and hemostatic potential
EP0575576B1 (de) Messung der thromblytischen Aktivität von Blut
KR101299418B1 (ko) 혈전탄성초음파영상 기법을 사용하여 인자 xⅲ와 섬유소원결핍 상태를 식별하는 방법
Sashindranath et al. The mode of anesthesia influences outcome in mouse models of arterial thrombosis
ATE536889T1 (de) Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
DE60144242D1 (de) Reagens und kit zur bestimmung der globalen gerinnungsfähigkeit und des hämostatischen potentials
Brass et al. Hemostatic thrombus formation in flowing blood
Pluthero et al. Decreased in vitro thrombin generation and clot stability in human FXII-null blood and plasma.
Hoppensteadt et al. Factor X values as a means to assess the extent of oral anticoagulation in patients receiving antithrombin drugs
Crossen et al. Investigating thrombin-loaded fibrin in whole blood clot microfluidic assay via fluorogenic peptide
DE60229297D1 (de) Verfahren und vorrichtung zur bestimmung des durchdringens von gasförmigen substanzen durch eine membran
DE69427723D1 (de) Verfahren zur Bestimmung der Wirksamkeit einer Testsubstanz

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties