DE60139543D1 - Multipotente neurale stammzellen aus hautgewebe und deren verwendungen - Google Patents

Multipotente neurale stammzellen aus hautgewebe und deren verwendungen

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Publication number
DE60139543D1
DE60139543D1 DE60139543T DE60139543T DE60139543D1 DE 60139543 D1 DE60139543 D1 DE 60139543D1 DE 60139543 T DE60139543 T DE 60139543T DE 60139543 T DE60139543 T DE 60139543T DE 60139543 D1 DE60139543 D1 DE 60139543D1
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Prior art keywords
stem cells
multipotente
neural stem
skin fabrics
fabrics
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Expired - Lifetime
Application number
DE60139543T
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English (en)
Inventor
Jean Toma
Mahnaz Akhavan
Karl J Fernandes
Mathieu Fortier
Freda Miller
Andrew Golster
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McGill University
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McGill University
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Publication of DE60139543D1 publication Critical patent/DE60139543D1/de
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0623Stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0619Neurons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/195Heregulin, neu differentiation factor
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/235Leukemia inhibitory factor [LIF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
    • CCHEMISTRY; METALLURGY
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    • C12N2510/00Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
DE60139543T 2000-01-24 2001-01-24 Multipotente neurale stammzellen aus hautgewebe und deren verwendungen Expired - Lifetime DE60139543D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49042200A 2000-01-24 2000-01-24
US09/670,049 US6787355B1 (en) 1996-08-26 2000-09-25 Multipotent neural stem cells from peripheral tissues and uses thereof
PCT/CA2001/000047 WO2001053461A1 (en) 2000-01-24 2001-01-24 Multipotent neural stem cells from peripheral tissues and uses thereof

Publications (1)

Publication Number Publication Date
DE60139543D1 true DE60139543D1 (de) 2009-09-24

Family

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DE60139543T Expired - Lifetime DE60139543D1 (de) 2000-01-24 2001-01-24 Multipotente neurale stammzellen aus hautgewebe und deren verwendungen

Country Status (9)

Country Link
US (3) US6787355B1 (de)
EP (1) EP1255813B1 (de)
JP (1) JP2003525034A (de)
AT (1) ATE439429T1 (de)
AU (2) AU2821601A (de)
CA (1) CA2398239A1 (de)
DE (1) DE60139543D1 (de)
IL (2) IL150789A0 (de)
WO (1) WO2001053461A1 (de)

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Also Published As

Publication number Publication date
US20040033597A1 (en) 2004-02-19
AU2821601A (en) 2001-07-31
IL150789A (en) 2010-12-30
AU2001228216B2 (en) 2007-07-26
WO2001053461A9 (en) 2002-01-03
JP2003525034A (ja) 2003-08-26
US20090142834A1 (en) 2009-06-04
CA2398239A1 (en) 2001-07-26
US6787355B1 (en) 2004-09-07
ATE439429T1 (de) 2009-08-15
IL150789A0 (en) 2003-02-12
EP1255813A1 (de) 2002-11-13
WO2001053461A1 (en) 2001-07-26
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