DE60139543D1 - Multipotente neurale stammzellen aus hautgewebe und deren verwendungen - Google Patents
Multipotente neurale stammzellen aus hautgewebe und deren verwendungenInfo
- Publication number
- DE60139543D1 DE60139543D1 DE60139543T DE60139543T DE60139543D1 DE 60139543 D1 DE60139543 D1 DE 60139543D1 DE 60139543 T DE60139543 T DE 60139543T DE 60139543 T DE60139543 T DE 60139543T DE 60139543 D1 DE60139543 D1 DE 60139543D1
- Authority
- DE
- Germany
- Prior art keywords
- stem cells
- multipotente
- neural stem
- skin fabrics
- fabrics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/195—Heregulin, neu differentiation factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49042200A | 2000-01-24 | 2000-01-24 | |
US09/670,049 US6787355B1 (en) | 1996-08-26 | 2000-09-25 | Multipotent neural stem cells from peripheral tissues and uses thereof |
PCT/CA2001/000047 WO2001053461A1 (en) | 2000-01-24 | 2001-01-24 | Multipotent neural stem cells from peripheral tissues and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60139543D1 true DE60139543D1 (de) | 2009-09-24 |
Family
ID=27050050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60139543T Expired - Lifetime DE60139543D1 (de) | 2000-01-24 | 2001-01-24 | Multipotente neurale stammzellen aus hautgewebe und deren verwendungen |
Country Status (9)
Country | Link |
---|---|
US (3) | US6787355B1 (de) |
EP (1) | EP1255813B1 (de) |
JP (1) | JP2003525034A (de) |
AT (1) | ATE439429T1 (de) |
AU (2) | AU2821601A (de) |
CA (1) | CA2398239A1 (de) |
DE (1) | DE60139543D1 (de) |
IL (2) | IL150789A0 (de) |
WO (1) | WO2001053461A1 (de) |
Families Citing this family (65)
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US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
US7544509B2 (en) | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
EP1367899A4 (de) | 2001-02-14 | 2004-07-28 | Leo T Furcht | Multipotente adulte stammzellen, ausgangsmaterial dafür, verfahren zu ihrer gewinnung und erhaltung, differenzierungsmethoden dafür, verfahren zu ihrer verwendung, sowie von ihnen stammende zellen |
US7838292B1 (en) * | 2001-03-29 | 2010-11-23 | University Of Louisville Research Foundation, Inc. | Methods for obtaining adult human olfactory progenitor cells |
WO2003060082A2 (en) | 2002-01-14 | 2003-07-24 | The Board Of Trustees Of The University Of Illinois | Use of modified pyrimidine compounds to promote stem cell migration and proliferation |
AUPS187202A0 (en) * | 2002-04-22 | 2002-05-30 | Griffith University | Method for culturing stem cells |
DE10393633D2 (en) * | 2002-08-16 | 2005-07-07 | Ulrich Drews | Verfahren zur gewinnung von diploiden, pluripotenten stammzellen sowie deren verwendung |
WO2004078944A2 (en) | 2003-03-05 | 2004-09-16 | Maine Medical Center Research Institute | Thrombin, soluble jaggedi, and trap and growth of stem cells |
EP1636349A1 (de) * | 2003-06-06 | 2006-03-22 | The Hospital for Sick Children | Stammzellen aus der neuralleiste und deren verwendung |
US7186557B2 (en) * | 2003-06-13 | 2007-03-06 | Isolagen Technologies, Inc. | Methods of producing neurons |
AU2004252570C1 (en) * | 2003-06-27 | 2012-03-01 | Ethicon, Incorporated | Soft tissue repair and regeneration using postpartum-derived cells |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
WO2005003320A2 (en) | 2003-07-02 | 2005-01-13 | Regents Of The University Of Minnesota | Neuronal differentiation of stem cells |
AU2004288722A1 (en) | 2003-11-04 | 2005-05-26 | U.S. Department Of Veterans Affairs | Stem cell culture medium and method of using said medium and the cells |
EP1718732B1 (de) * | 2004-01-27 | 2013-10-30 | The Hospital for Sick Children Research Institute | Verfahren zur herstellung und verwendung von der haut abgeleiteter stammzellen |
FR2870854B1 (fr) * | 2004-05-26 | 2010-12-31 | Oreal | Utilisation du lif en ingenierie cellulaire et tissulaire |
US8080420B2 (en) | 2004-10-22 | 2011-12-20 | University Of Central Florida Research Foundation, Inc. | Methods and products for biasing cellular development |
KR100768533B1 (ko) | 2004-11-30 | 2007-10-18 | 재단법인 한국원자력의학원 | 피부 진피로부터 신경전구세포를 유도하는 방법 및 중추또는 말초 신경계 손상 치료제 |
US20060166361A1 (en) * | 2004-12-21 | 2006-07-27 | Agnieszka Seyda | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
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US20060171930A1 (en) * | 2004-12-21 | 2006-08-03 | Agnieszka Seyda | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
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EP1833496B1 (de) | 2004-12-23 | 2013-07-31 | Ethicon, Incorporated | Behandlung von schlaganfall und anderer akuter degenerativer nervenerkrankungen mit post partum erhaltenen zellen |
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US20070123448A1 (en) * | 2005-11-23 | 2007-05-31 | The Hospital For Sick Children | Novel chemical entities affecting neuroblastoma tumor-initiating cells |
CN101374946B (zh) * | 2005-12-16 | 2017-07-18 | 伊西康公司 | 用于在组织相容性不匹配的移植中抑制有害的免疫反应的组合物和方法 |
JP5179376B2 (ja) * | 2005-12-19 | 2013-04-10 | エシコン・インコーポレイテッド | ローラーボトルでの分娩後取り出し細胞の体外増殖 |
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US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
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US10357517B1 (en) | 2012-10-01 | 2019-07-23 | University Of South Florida | Methods of treating epilepsy using neural stem cells that express nanog, SSEA-4, OCT-4, MIR-34B, MIR-34C and MIR-592 |
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US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
WO1999056759A1 (en) | 1998-05-07 | 1999-11-11 | University Of South Florida | Bone marrow cells as a source of neurons for brain and spinal cord repair |
CA2852534A1 (en) * | 1999-08-05 | 2001-02-15 | Abt Holding Company | Multipotent adult stem cells and methods for isolation |
-
2000
- 2000-09-25 US US09/670,049 patent/US6787355B1/en not_active Expired - Fee Related
-
2001
- 2001-01-24 IL IL15078901A patent/IL150789A0/xx unknown
- 2001-01-24 US US10/181,508 patent/US20040033597A1/en not_active Abandoned
- 2001-01-24 CA CA002398239A patent/CA2398239A1/en not_active Abandoned
- 2001-01-24 WO PCT/CA2001/000047 patent/WO2001053461A1/en active IP Right Grant
- 2001-01-24 DE DE60139543T patent/DE60139543D1/de not_active Expired - Lifetime
- 2001-01-24 EP EP01942663A patent/EP1255813B1/de not_active Expired - Lifetime
- 2001-01-24 AU AU2821601A patent/AU2821601A/xx active Pending
- 2001-01-24 AT AT01942663T patent/ATE439429T1/de not_active IP Right Cessation
- 2001-01-24 JP JP2001553922A patent/JP2003525034A/ja active Pending
- 2001-01-24 AU AU2001228216A patent/AU2001228216B2/en not_active Ceased
-
2002
- 2002-07-17 IL IL150789A patent/IL150789A/en not_active IP Right Cessation
-
2008
- 2008-05-05 US US12/149,616 patent/US20090142834A1/en not_active Abandoned
Also Published As
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CA2398239A1 (en) | 2001-07-26 |
US20040033597A1 (en) | 2004-02-19 |
ATE439429T1 (de) | 2009-08-15 |
US6787355B1 (en) | 2004-09-07 |
JP2003525034A (ja) | 2003-08-26 |
AU2821601A (en) | 2001-07-31 |
EP1255813A1 (de) | 2002-11-13 |
IL150789A0 (en) | 2003-02-12 |
IL150789A (en) | 2010-12-30 |
US20090142834A1 (en) | 2009-06-04 |
EP1255813B1 (de) | 2009-08-12 |
WO2001053461A9 (en) | 2002-01-03 |
AU2001228216B2 (en) | 2007-07-26 |
WO2001053461A1 (en) | 2001-07-26 |
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