DE60137507D1 - Verbesserte signaldetektion und kopplung in teststab-tests - Google Patents
Verbesserte signaldetektion und kopplung in teststab-testsInfo
- Publication number
- DE60137507D1 DE60137507D1 DE60137507T DE60137507T DE60137507D1 DE 60137507 D1 DE60137507 D1 DE 60137507D1 DE 60137507 T DE60137507 T DE 60137507T DE 60137507 T DE60137507 T DE 60137507T DE 60137507 D1 DE60137507 D1 DE 60137507D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- target nucleic
- sample solution
- capture
- tests
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Cable Accessories (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Instrument Details And Bridges, And Automatic Balancing Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Luminescent Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0016813.8A GB0016813D0 (en) | 2000-07-07 | 2000-07-07 | Improved dipstick assays (4) |
PCT/GB2001/003021 WO2002004667A2 (en) | 2000-07-07 | 2001-07-06 | Improved detection signal and capture in dipstick assays |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60137507D1 true DE60137507D1 (de) | 2009-03-12 |
Family
ID=9895290
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60137507T Expired - Lifetime DE60137507D1 (de) | 2000-07-07 | 2001-07-06 | Verbesserte signaldetektion und kopplung in teststab-tests |
Country Status (11)
Country | Link |
---|---|
US (2) | US20040053256A1 (de) |
EP (1) | EP1301627B1 (de) |
JP (2) | JP2004512498A (de) |
CN (2) | CN102174651A (de) |
AT (1) | ATE421597T1 (de) |
AU (2) | AU2001267750B2 (de) |
DE (1) | DE60137507D1 (de) |
ES (1) | ES2320097T3 (de) |
GB (1) | GB0016813D0 (de) |
TW (1) | TWI286160B (de) |
WO (1) | WO2002004667A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0025245D0 (en) | 2000-10-14 | 2000-11-29 | Lee Helen | Multiple target detection |
WO2004099438A1 (en) * | 2003-05-07 | 2004-11-18 | Coris Bioconcept Sprl | One step oligochromatographic device and method of use |
US7538202B2 (en) * | 2003-12-19 | 2009-05-26 | California Institute Of Technology | Enzyme-free isothermal exponential amplification of nucleic acids and nucleic acid analog signals |
ATE529533T1 (de) * | 2004-06-11 | 2011-11-15 | Evotec Ag | Verfahren zum nachweis von analyten in einer probe |
ATE549413T1 (de) * | 2005-05-30 | 2012-03-15 | Qiagen Gmbh | Vorrichtung und verfahren zur normalisierung von nukleinsäure-konzentrationen |
WO2008105814A2 (en) * | 2006-08-22 | 2008-09-04 | Los Alamos National Security, Llc | Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids |
GB0701253D0 (en) * | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
EP3067694A1 (de) | 2008-05-05 | 2016-09-14 | Los Alamos National Security, LLC | Vorbereitung von nukleinsäureproben auf lateralflussbasis und passive strömungssteuerung |
DE102008047790A1 (de) * | 2008-09-17 | 2010-04-15 | Qiagen Gmbh | Verfahren zur Normierung des Gehalts von Biomolekülen in einer Probe |
WO2012027547A2 (en) * | 2010-08-25 | 2012-03-01 | Columbia University | Quantitative total definition of biologically active sequence elements |
JPWO2012070618A1 (ja) | 2010-11-24 | 2014-05-19 | 株式会社カネカ | 増幅核酸検出方法及び検出デバイス |
KR101508670B1 (ko) | 2011-04-20 | 2015-04-07 | 메사 테크 인터내셔널, 인코포레이티드 | 핵산 검출 및 동정을 위한 통합 장치 |
CN106996973A (zh) * | 2014-07-01 | 2017-08-01 | 艾博生物医药(杭州)有限公司 | 一种样本检测装置 |
AU2016253147B2 (en) | 2015-04-24 | 2021-07-22 | Mesa Biotech, Inc. | Fluidic test cassette |
WO2016203267A2 (en) | 2015-06-19 | 2016-12-22 | Cambridge Enterprise Limited | Diagnosis and treatment of infectious disease |
CN105403707B (zh) * | 2015-09-29 | 2017-05-17 | 南方医科大学 | 一种检测靶物质的信号放大方法及使用该方法的免疫层析试纸和装置 |
CN112881494A (zh) * | 2020-11-09 | 2021-06-01 | 北京大学 | 多指标检测用场效应晶体管型生物传感器件 |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
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US4740468A (en) * | 1985-02-14 | 1988-04-26 | Syntex (U.S.A.) Inc. | Concentrating immunochemical test device and method |
GB8509367D0 (en) * | 1985-04-12 | 1985-05-15 | Amersham Int Plc | Nucleic acid hybridisation |
US4751177A (en) * | 1985-06-13 | 1988-06-14 | Amgen | Methods and kits for performing nucleic acid hybridization assays |
US4806311A (en) * | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having labeled reagent concentration zone |
AU7015287A (en) | 1986-03-19 | 1987-09-24 | Cetus Corporation | Detection of nucleic acid sequence using liquid hybridization method |
US4960691A (en) * | 1986-09-29 | 1990-10-02 | Abbott Laboratories | Chromatographic test strip for determining ligands or receptors |
US5310650A (en) * | 1986-09-29 | 1994-05-10 | Abbott Laboratoires | Method and device for improved reaction kinetics in nucleic acid hybridizations |
IL86164A0 (en) * | 1987-04-28 | 1988-11-15 | Tamir Biotechnology Ltd | Improved dna probes |
US4855240A (en) * | 1987-05-13 | 1989-08-08 | Becton Dickinson And Company | Solid phase assay employing capillary flow |
US5212059A (en) * | 1988-01-11 | 1993-05-18 | Microprobe Corporation | Oligonucleotide probes for the detection of periodontal pathogens |
US5109124A (en) * | 1988-06-01 | 1992-04-28 | Biogen, Inc. | Nucleic acid probe linked to a label having a terminal cysteine |
CA1308022C (en) * | 1988-08-11 | 1992-09-29 | Eleftherios P. Diamandis | Multiple fluorescence labelling with europium chelators |
EP0387696B1 (de) | 1989-03-17 | 1997-08-27 | Abbott Laboratories | Verfahren und Vorrichtung zur Hybridisierung von Nukleinsäure mit verbesserter Reaktionskinetik |
ATE152777T1 (de) * | 1989-12-04 | 1997-05-15 | Microprobe Corp | Verstärkter einfang von ziel-nukleinsäuren mittels verwendung von oligonukleotiden, die kovalent an polymere gebunden sind |
GB9009980D0 (en) | 1990-05-03 | 1990-06-27 | Amersham Int Plc | Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides |
US5491224A (en) * | 1990-09-20 | 1996-02-13 | Bittner; Michael L. | Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture |
EP0497464A1 (de) | 1991-01-31 | 1992-08-05 | Amoco Corporation | Schnellnachweis von Mikroben durch in situ-Hybridisation in wässeriger Suspension |
US5451504A (en) * | 1991-07-29 | 1995-09-19 | Serex, Inc. | Method and device for detecting the presence of analyte in a sample |
EP0672175A4 (de) | 1991-12-23 | 1997-08-06 | Chiron Corp | Hav-proben in sandwichhybridisierungsverfahren in lösungen. |
US5464945A (en) | 1992-08-28 | 1995-11-07 | Hoffmann-La Roche Inc. | Oligonucleotide probes specific for the human alpha satellite locus |
WO1994023299A1 (en) * | 1993-03-31 | 1994-10-13 | Quidel Corporation | Multiple assay device |
JPH09500378A (ja) * | 1993-07-02 | 1997-01-14 | リンクス セラピューティクス,インコーポレイティド | 枝分れされそして複雑に結合された高分子構造体の集中的合成 |
US6468742B2 (en) * | 1993-11-01 | 2002-10-22 | Nanogen, Inc. | Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip |
CA2176348C (en) | 1993-11-12 | 2004-11-02 | Sanjay Tyagi | Hybridization probes for nucleic acid detection, universal stems, methods and kits |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
WO1995027081A1 (en) * | 1994-03-31 | 1995-10-12 | E.I. Du Pont De Nemours And Company | A method for detection of nucleic acid fragments |
US6037127A (en) * | 1994-03-31 | 2000-03-14 | E. I. Du Pont De Nemours And Company | Method for detection of non-denatured nucleic acid fragments |
US6653066B1 (en) * | 1994-06-17 | 2003-11-25 | Trinity Biotech | Device and method for detecting polyvalent substances |
US5521289A (en) * | 1994-07-29 | 1996-05-28 | Nanoprobes, Inc. | Small organometallic probes |
FR2724461B1 (fr) * | 1994-09-09 | 1996-12-20 | Prolabo Sa | Microsphere de latex biotinylee, procede de preparation d'une telle microsphere et utilisation en tant qu'agent de detection biologique |
US5747248A (en) * | 1994-12-05 | 1998-05-05 | Chiron Corporation | Discontinuous probe design using hybritope mapping |
WO1996029097A1 (en) * | 1995-03-21 | 1996-09-26 | Research Corporation Technologies, Inc. | Stem-loop and circular oligonucleotides |
DE19537952A1 (de) * | 1995-10-12 | 1997-04-17 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis eines Analyten |
US5874216A (en) * | 1996-02-23 | 1999-02-23 | Ensys Environmental Products, Inc. | Indirect label assay device for detecting small molecules and method of use thereof |
US5824478A (en) * | 1996-04-30 | 1998-10-20 | Vysis, Inc. | Diagnostic methods and probes |
US5916750A (en) * | 1997-01-08 | 1999-06-29 | Biogenex Laboratories | Multifunctional linking reagents for synthesis of branched oligomers |
WO1998036278A1 (en) * | 1997-02-15 | 1998-08-20 | Beth Israel Deaconess Medical Center, Inc. | Multiple-site antibody capture immunoassays and kits |
JP2001514859A (ja) * | 1997-09-04 | 2001-09-18 | バイエル コーポレイション | クエンチ可能な蛍光標識を有するオリゴヌクレオチドプローブおよびその使用方法 |
US6573045B1 (en) | 1998-06-05 | 2003-06-03 | Ribotargets, Ltd. | Methods and kits for discovery of RNA-binding compounds |
US6290839B1 (en) * | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
US20020012913A1 (en) * | 1998-09-15 | 2002-01-31 | Kevin L. Gunderson | Nucleic acid analysis using complete n-mer arrays |
GB0016836D0 (en) * | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
GB0016833D0 (en) * | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (2) |
GB0016814D0 (en) * | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (3) |
GB0025245D0 (en) * | 2000-10-14 | 2000-11-29 | Lee Helen | Multiple target detection |
GB0029154D0 (en) * | 2000-11-30 | 2001-01-17 | Lee Helen | Signal enhancement with multiple labelled-antibodies |
-
2000
- 2000-07-07 GB GBGB0016813.8A patent/GB0016813D0/en not_active Ceased
-
2001
- 2001-07-06 JP JP2002509520A patent/JP2004512498A/ja not_active Withdrawn
- 2001-07-06 EP EP01945536A patent/EP1301627B1/de not_active Expired - Lifetime
- 2001-07-06 CN CN201110035702XA patent/CN102174651A/zh active Pending
- 2001-07-06 AT AT01945536T patent/ATE421597T1/de not_active IP Right Cessation
- 2001-07-06 AU AU2001267750A patent/AU2001267750B2/en not_active Expired
- 2001-07-06 ES ES01945536T patent/ES2320097T3/es not_active Expired - Lifetime
- 2001-07-06 AU AU6775001A patent/AU6775001A/xx active Pending
- 2001-07-06 CN CN018153070A patent/CN1452663B/zh not_active Expired - Lifetime
- 2001-07-06 WO PCT/GB2001/003021 patent/WO2002004667A2/en active Application Filing
- 2001-07-06 TW TW090116570A patent/TWI286160B/zh not_active IP Right Cessation
- 2001-07-06 DE DE60137507T patent/DE60137507D1/de not_active Expired - Lifetime
- 2001-07-06 US US10/332,133 patent/US20040053256A1/en not_active Abandoned
-
2011
- 2011-09-29 JP JP2011215502A patent/JP2012008148A/ja active Pending
-
2013
- 2013-12-19 US US14/134,422 patent/US20150099265A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001267750B2 (en) | 2007-08-16 |
ES2320097T3 (es) | 2009-05-19 |
EP1301627A2 (de) | 2003-04-16 |
US20150099265A1 (en) | 2015-04-09 |
GB0016813D0 (en) | 2000-08-30 |
JP2004512498A (ja) | 2004-04-22 |
WO2002004667A3 (en) | 2002-12-27 |
CN1452663B (zh) | 2011-11-23 |
CN102174651A (zh) | 2011-09-07 |
CN1452663A (zh) | 2003-10-29 |
AU6775001A (en) | 2002-01-21 |
EP1301627B1 (de) | 2009-01-21 |
US20040053256A1 (en) | 2004-03-18 |
JP2012008148A (ja) | 2012-01-12 |
TWI286160B (en) | 2007-09-01 |
WO2002004667A2 (en) | 2002-01-17 |
ATE421597T1 (de) | 2009-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |