DE60131675D1 - Neue verwendung von substanzen mit kombinierten 5-ht1a agonistischen und serotonin reuptake inhibitor-aktivitäten - Google Patents

Neue verwendung von substanzen mit kombinierten 5-ht1a agonistischen und serotonin reuptake inhibitor-aktivitäten

Info

Publication number
DE60131675D1
DE60131675D1 DE60131675T DE60131675T DE60131675D1 DE 60131675 D1 DE60131675 D1 DE 60131675D1 DE 60131675 T DE60131675 T DE 60131675T DE 60131675 T DE60131675 T DE 60131675T DE 60131675 D1 DE60131675 D1 DE 60131675D1
Authority
DE
Germany
Prior art keywords
substances
combined
reuptake inhibitor
new utilization
inhibitor activities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60131675T
Other languages
English (en)
Other versions
DE60131675T2 (de
Inventor
Gerd Bartoszyk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE60131675D1 publication Critical patent/DE60131675D1/de
Publication of DE60131675T2 publication Critical patent/DE60131675T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60131675T 2000-11-14 2001-10-16 Neue verwendung von substanzen mit kombinierten 5-ht1a agonistischen und serotonin reuptake inhibitor-aktivitäten Expired - Lifetime DE60131675T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00124815 2000-11-14
EP00124815 2000-11-14
PCT/EP2001/011952 WO2002040024A1 (en) 2000-11-14 2001-10-16 Novel uses of combined 5-ht1a agonists and serotonin reuptake inhibitors

Publications (2)

Publication Number Publication Date
DE60131675D1 true DE60131675D1 (de) 2008-01-10
DE60131675T2 DE60131675T2 (de) 2008-11-20

Family

ID=8170369

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60131675T Expired - Lifetime DE60131675T2 (de) 2000-11-14 2001-10-16 Neue verwendung von substanzen mit kombinierten 5-ht1a agonistischen und serotonin reuptake inhibitor-aktivitäten

Country Status (22)

Country Link
US (1) US20040082594A1 (de)
EP (1) EP1333832B1 (de)
JP (1) JP2004513924A (de)
KR (1) KR20030059244A (de)
CN (1) CN1222291C (de)
AR (1) AR031335A1 (de)
AU (2) AU1502702A (de)
BR (1) BR0115296A (de)
CA (1) CA2428511C (de)
CZ (1) CZ302484B6 (de)
DE (1) DE60131675T2 (de)
ES (1) ES2296820T3 (de)
HK (1) HK1060697A1 (de)
HU (1) HUP0302751A3 (de)
MX (1) MXPA03004166A (de)
NO (1) NO20032148D0 (de)
PL (1) PL204331B1 (de)
RU (1) RU2288719C2 (de)
SK (1) SK287337B6 (de)
UA (1) UA79583C2 (de)
WO (1) WO2002040024A1 (de)
ZA (1) ZA200304606B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10305739A1 (de) * 2003-02-11 2004-08-19 Merck Patent Gmbh Benzofuranderivate
WO2005061455A1 (en) 2003-12-23 2005-07-07 H. Lundbeck A/S 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
EP1732610A2 (de) 2004-03-26 2006-12-20 Baylor University Gezielte inhibitoren der serotonin-wiederaufname
AR052308A1 (es) 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
WO2006034788A1 (en) * 2004-09-28 2006-04-06 Merck Patent Gmbh Combinations of n-(indolecarbonyl-)piperazine derivatives and serotonin reuptake inhibitors
AR054393A1 (es) 2005-06-17 2007-06-20 Lundbeck & Co As H Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos.
US7629473B2 (en) 2005-06-17 2009-12-08 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-aryl amine derivatives
CN101563080A (zh) * 2006-08-11 2009-10-21 帝斯曼知识产权资产管理有限公司 用于治疗中枢神经病症的藁本内酯衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4333254A1 (de) * 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
DE19512639A1 (de) * 1995-04-05 1996-10-10 Merck Patent Gmbh Benzonitrile und -fluoride
DE19637237A1 (de) * 1996-09-13 1998-03-19 Merck Patent Gmbh Piperazin-Derivate
DE19730989A1 (de) * 1997-07-18 1999-01-21 Merck Patent Gmbh Piperazin-Derivate
AU5033899A (en) * 1998-07-20 2000-02-14 Merck Patent Gmbh Biphenyl derivatives

Also Published As

Publication number Publication date
EP1333832B1 (de) 2007-11-28
CA2428511C (en) 2009-12-29
RU2288719C2 (ru) 2006-12-10
CZ20031433A3 (cs) 2003-09-17
CA2428511A1 (en) 2002-05-23
AR031335A1 (es) 2003-09-17
HK1060697A1 (en) 2004-08-20
CN1222291C (zh) 2005-10-12
HUP0302751A3 (en) 2007-06-28
SK6382003A3 (en) 2003-11-04
JP2004513924A (ja) 2004-05-13
PL360310A1 (en) 2004-09-06
AU2002215027B2 (en) 2006-10-05
HUP0302751A2 (hu) 2003-11-28
CZ302484B6 (cs) 2011-06-08
EP1333832A1 (de) 2003-08-13
DE60131675T2 (de) 2008-11-20
CN1474691A (zh) 2004-02-11
AU1502702A (en) 2002-05-27
BR0115296A (pt) 2003-09-02
SK287337B6 (sk) 2010-07-07
WO2002040024A1 (en) 2002-05-23
ZA200304606B (en) 2004-09-13
NO20032148L (no) 2003-05-13
US20040082594A1 (en) 2004-04-29
KR20030059244A (ko) 2003-07-07
MXPA03004166A (es) 2003-09-22
ES2296820T3 (es) 2008-05-01
NO20032148D0 (no) 2003-05-13
PL204331B1 (pl) 2010-01-29
UA79583C2 (en) 2007-07-10

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